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Cleanup-MOFs TERMINATED

Decontamination of emerging pollutant using porous Metal-Organic Frameworks (MOFs) and silica-MOFs composites

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 Cleanup-MOFs project word cloud

Explore the words cloud of the Cleanup-MOFs project. It provides you a very rough idea of what is the project "Cleanup-MOFs" about.

weak    almost    specially    vast    functionalization    pollutant    plants    prescribed    frameworks    versatile    ranging    structural    detoxification    degraded    combinations    broken    action    mimic    substances    attracted    removal    species    illicit    sewers    advantages    treatment    human    attempted    adverse    environment    industrial    compounds    porosity    groups    functional    remove    poisoning    pharmaceuticals    context    adsorbent    therapeutic    endocrine    pollutants    heath    academic    source    poorly    harmful    linker    worldwide    25    shapes    nanoporous    ppcps    crystalline    enter    regarded    health    released    mofs    little    composition    misadventures    lt    sizes    equipped    wastewater    drown    ingestion    public    class    causes    majority    micro    materials    severe    unfortunately    passing    mesopore    hormones    modulation    contaminants    physicochemical    antidotes    organic    adsorbed    inhibit    personal    care    variability    quantities    domains    panel    degradation    death    processed    disruptors    pore    suicide    pharmacological    metal    infinite    drug    easily   

Project "Cleanup-MOFs" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-12-21

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

Pharmaceuticals and Personal Care Products as Pollutants (PPCPs) are regarded as an emerging class of contaminants and are often released directly into the environment after passing through wastewater treatment plants that are not equipped to remove them. Some PPCPs are easily broken drown and processed, but others are not easily degraded and processed, so they enter sewers. Although little is known about potential adverse effects on non-target species, these substances can be endocrine disruptors that mimic, enhance or inhibit the action of hormones. These compounds are a source of concern because they are widely used and then released in large quantities.

On the other hand, the therapeutic misadventures, illicit drug ingestion or attempted suicide by using of harmful substances is a major worldwide public health problem that causes both a significant cost and severe heath problems, even death. Unfortunately, for the vast majority of these poisoning, there are no specific pharmacological antidotes and currently available detoxification methods are weak (<25% PPCPs adsorbed) and poorly prescribed.

In this context, a new class of crystalline nanoporous materials known as Metal Organic Frameworks (MOFs) has attracted an increasing attention from academic and industrial domains. Compared to classical adsorbent materials, MOFs present several advantages: a versatile composition, which allows almost infinite combinations, a large structural variability, an important porosity with a large panel of pore sizes and shapes, ranging from the micro to the mesopore, and the easy modulation of their physicochemical properties by the simple functionalization of the organic linker, including different functional groups.

Taking into account MOFs advantages, the objective of the present project is to develop MOFs specially tailored for the removal and degradation of very harmful pollutant from wastewater, as well as for human detoxification.

 Publications

year authors and title journal last update
List of publications.
2018 Sara Rojas, Isabel Colinet, Denise Cunha, Tania Hidalgo, Fabrice Salles, Christian Serre, Nathalie Guillou, Patricia Horcajada
Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal–Organic Frameworks in View of Cutaneous Administration
published pages: 2994-3003, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b00185
ACS Omega 3/3 2019-06-13
2018 Sara Rojas, Tarek Baati, Leila Njim, Lisbeth Manchego, Fadoua Neffati, Nissem Abdeljelil, Saad Saguem, Christian Serre, Mohamed Fadhel Najjar, Abdelfateh Zakhama, Patricia Horcajada
Metal–Organic Frameworks as Efficient Oral Detoxifying Agents
published pages: 9581-9586, ISSN: 0002-7863, DOI: 10.1021/jacs.8b04435
Journal of the American Chemical Society 140/30 2019-06-13

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