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Cleanup-MOFs TERMINATED

Decontamination of emerging pollutant using porous Metal-Organic Frameworks (MOFs) and silica-MOFs composites

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 Cleanup-MOFs project word cloud

Explore the words cloud of the Cleanup-MOFs project. It provides you a very rough idea of what is the project "Cleanup-MOFs" about.

suicide    modulation    misadventures    25    context    mofs    porosity    plants    harmful    nanoporous    functional    sizes    degraded    death    unfortunately    detoxification    easily    combinations    shapes    adverse    almost    industrial    passing    infinite    variability    functionalization    pollutant    adsorbent    inhibit    crystalline    action    wastewater    organic    academic    worldwide    degradation    disruptors    care    human    drug    pollutants    ppcps    adsorbed    remove    drown    public    treatment    compounds    panel    pore    domains    attempted    sewers    groups    heath    broken    therapeutic    structural    regarded    mimic    endocrine    pharmaceuticals    hormones    released    frameworks    health    severe    pharmacological    attracted    poisoning    weak    source    causes    vast    class    quantities    prescribed    personal    versatile    little    equipped    specially    poorly    processed    mesopore    substances    removal    linker    lt    enter    ingestion    environment    antidotes    advantages    ranging    species    composition    contaminants    illicit    majority    physicochemical    micro    materials    metal   

Project "Cleanup-MOFs" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-12-21

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

Pharmaceuticals and Personal Care Products as Pollutants (PPCPs) are regarded as an emerging class of contaminants and are often released directly into the environment after passing through wastewater treatment plants that are not equipped to remove them. Some PPCPs are easily broken drown and processed, but others are not easily degraded and processed, so they enter sewers. Although little is known about potential adverse effects on non-target species, these substances can be endocrine disruptors that mimic, enhance or inhibit the action of hormones. These compounds are a source of concern because they are widely used and then released in large quantities.

On the other hand, the therapeutic misadventures, illicit drug ingestion or attempted suicide by using of harmful substances is a major worldwide public health problem that causes both a significant cost and severe heath problems, even death. Unfortunately, for the vast majority of these poisoning, there are no specific pharmacological antidotes and currently available detoxification methods are weak (<25% PPCPs adsorbed) and poorly prescribed.

In this context, a new class of crystalline nanoporous materials known as Metal Organic Frameworks (MOFs) has attracted an increasing attention from academic and industrial domains. Compared to classical adsorbent materials, MOFs present several advantages: a versatile composition, which allows almost infinite combinations, a large structural variability, an important porosity with a large panel of pore sizes and shapes, ranging from the micro to the mesopore, and the easy modulation of their physicochemical properties by the simple functionalization of the organic linker, including different functional groups.

Taking into account MOFs advantages, the objective of the present project is to develop MOFs specially tailored for the removal and degradation of very harmful pollutant from wastewater, as well as for human detoxification.

 Publications

year authors and title journal last update
List of publications.
2018 Sara Rojas, Isabel Colinet, Denise Cunha, Tania Hidalgo, Fabrice Salles, Christian Serre, Nathalie Guillou, Patricia Horcajada
Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal–Organic Frameworks in View of Cutaneous Administration
published pages: 2994-3003, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b00185
ACS Omega 3/3 2019-06-13
2018 Sara Rojas, Tarek Baati, Leila Njim, Lisbeth Manchego, Fadoua Neffati, Nissem Abdeljelil, Saad Saguem, Christian Serre, Mohamed Fadhel Najjar, Abdelfateh Zakhama, Patricia Horcajada
Metal–Organic Frameworks as Efficient Oral Detoxifying Agents
published pages: 9581-9586, ISSN: 0002-7863, DOI: 10.1021/jacs.8b04435
Journal of the American Chemical Society 140/30 2019-06-13

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