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Cleanup-MOFs TERMINATED

Decontamination of emerging pollutant using porous Metal-Organic Frameworks (MOFs) and silica-MOFs composites

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 Cleanup-MOFs project word cloud

Explore the words cloud of the Cleanup-MOFs project. It provides you a very rough idea of what is the project "Cleanup-MOFs" about.

25    removal    specially    structural    therapeutic    remove    pollutants    easily    drown    attracted    frameworks    pore    antidotes    almost    academic    drug    lt    micro    class    contaminants    pollutant    misadventures    care    action    panel    linker    sewers    degradation    combinations    wastewater    endocrine    environment    hormones    suicide    metal    ranging    quantities    enter    physicochemical    equipped    nanoporous    functional    groups    ppcps    pharmacological    variability    unfortunately    mimic    broken    detoxification    domains    treatment    illicit    vast    worldwide    attempted    plants    ingestion    processed    source    porosity    passing    mesopore    human    severe    functionalization    context    causes    adsorbed    pharmaceuticals    materials    versatile    death    released    organic    adverse    industrial    personal    compounds    harmful    mofs    disruptors    little    weak    substances    species    health    public    sizes    degraded    crystalline    poisoning    shapes    majority    modulation    advantages    composition    heath    adsorbent    regarded    prescribed    poorly    inhibit    infinite   

Project "Cleanup-MOFs" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-12-21

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

Pharmaceuticals and Personal Care Products as Pollutants (PPCPs) are regarded as an emerging class of contaminants and are often released directly into the environment after passing through wastewater treatment plants that are not equipped to remove them. Some PPCPs are easily broken drown and processed, but others are not easily degraded and processed, so they enter sewers. Although little is known about potential adverse effects on non-target species, these substances can be endocrine disruptors that mimic, enhance or inhibit the action of hormones. These compounds are a source of concern because they are widely used and then released in large quantities.

On the other hand, the therapeutic misadventures, illicit drug ingestion or attempted suicide by using of harmful substances is a major worldwide public health problem that causes both a significant cost and severe heath problems, even death. Unfortunately, for the vast majority of these poisoning, there are no specific pharmacological antidotes and currently available detoxification methods are weak (<25% PPCPs adsorbed) and poorly prescribed.

In this context, a new class of crystalline nanoporous materials known as Metal Organic Frameworks (MOFs) has attracted an increasing attention from academic and industrial domains. Compared to classical adsorbent materials, MOFs present several advantages: a versatile composition, which allows almost infinite combinations, a large structural variability, an important porosity with a large panel of pore sizes and shapes, ranging from the micro to the mesopore, and the easy modulation of their physicochemical properties by the simple functionalization of the organic linker, including different functional groups.

Taking into account MOFs advantages, the objective of the present project is to develop MOFs specially tailored for the removal and degradation of very harmful pollutant from wastewater, as well as for human detoxification.

 Publications

year authors and title journal last update
List of publications.
2018 Sara Rojas, Isabel Colinet, Denise Cunha, Tania Hidalgo, Fabrice Salles, Christian Serre, Nathalie Guillou, Patricia Horcajada
Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal–Organic Frameworks in View of Cutaneous Administration
published pages: 2994-3003, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b00185
ACS Omega 3/3 2019-06-13
2018 Sara Rojas, Tarek Baati, Leila Njim, Lisbeth Manchego, Fadoua Neffati, Nissem Abdeljelil, Saad Saguem, Christian Serre, Mohamed Fadhel Najjar, Abdelfateh Zakhama, Patricia Horcajada
Metal–Organic Frameworks as Efficient Oral Detoxifying Agents
published pages: 9581-9586, ISSN: 0002-7863, DOI: 10.1021/jacs.8b04435
Journal of the American Chemical Society 140/30 2019-06-13

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