Explore the words cloud of the GolgiBiosSys project. It provides you a very rough idea of what is the project "GolgiBiosSys" about.
The following table provides information about the project.
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
|Coordinator Country||Switzerland [CH]|
|Total cost||187˙419 €|
|EC max contribution||187˙419 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2016-05-01 to 2018-04-30|
Take a look of project's partnership.
|1||EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH||CH (ZUERICH)||coordinator||187˙419.00|
The Golgi apparatus is a system of organised membrane structures that performs pivotal cell functions: biosynthesis and secretion of polysaccharides, protein and lipid glycosylation. The relevance of this organelle is measured by the amount of biomaterial produced by its activity. The highly abundant polysaccharides account for at least a third of all renewable organic carbon on Earth and are of great importance to the biosphere and to humanity, providing food, fibre and fuel. The functionality of the Golgi is thought to be governed by molecular organisational features, as the precise arrangement of its membrane proteins. Each of the numerous biosynthetic pathways performed in the Golgi requires the cooperative and orchestrated action and interaction of several different enzymes and auxiliary proteins. Currently very little is known about the composition and sub-Golgi localisation of such multiprotein systems. Firstly, a comprehensive insight into the interaction map of the Golgi proteome is needed. I propose to develop and apply a technique that will allow high-throughput assignment of membrane protein interactions, and identify stoichiometries. An experimental design is presented based on separation of membrane protein complexes in conjunction with state of the art quantitative proteomic approaches. Secondly, the results will be validated on selected multiprotein systems by immunoprecipitation and functional biochemical studies on knockout lines. Thirdly, the data will be used to model the interactions by protein-protein docking. The accomplishment of this project will provide new insights into the organisation and activity of the biosynthetic systems. Such insight is of great value to the production of specific polysaccharides, tailored to yield less recalcitrant material for the bioenergy and carbohydrate industries. Through this work I aim to deepen my academic expertise, gain technical and leadership skills and to establish myself as an independent researcher.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "GOLGIBIOSSYS" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "GOLGIBIOSSYS" are provided by the European Opendata Portal: CORDIS opendata.
Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological ResponsesRead More
Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and IconographyRead More
Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. ElegansRead More