Opendata, web and dolomites

RADIcAL SIGNED

Non-invasive rapid assessment of chronic liver disease using Magnetic Resonance Imaging with LiverMultiScan

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 RADIcAL project word cloud

Explore the words cloud of the RADIcAL project. It provides you a very rough idea of what is the project "RADIcAL" about.

fat    stratifying    clearance    burden    people    alcoholic    prospective    transplant    invasive    assure    trial    medical    biopsy    staging    suspected    optimal    450    reluctant    randomised    million    displays    accuracy    silent    specificity    nafld    causes    killers    clinicians    risks    diagnostic    clinical    surface    radical    sensitivity    entails    validate    untreated    software    patient    diagnosing    diseases    treatable    reimbursement    quantitative    validation    additional    treatment    fatty    nash    assessing    huge    worldwide    steatohepatitis    magnetic    centre    regulatory    resonance    perspectum    livermultiscan    risk    forms    pd    trials    stratification    tool    market    accumulation    imaging    economic    diagnostics    added    sub    serial    cirrhosis    signs    symptoms    liver    patients    rejection    health    suffer    ltd    accurate    costly    stages    population    effectiveness    lack    chronic    acceptance    monitoring    socio    broad    carries    disease    standard    care   

Project "RADIcAL" data sheet

The following table provides information about the project.

Coordinator
PERSPECTUM LTD 

Organization address
address: GEMINI ONE, 5520 JOHN SMITH DRIVE OXFORD BUSINESS PARK SOUTH
city: OXFORD
postcode: OX4 2LL
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.radical2020.eu
 Total cost 3˙460˙486 €
 EC max contribution 3˙460˙486 € (100%)
 Programme 1. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
2. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2015
 Funding Scheme SME-2
 Starting year 2016
 Duration (year-month-day) from 2016-07-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PERSPECTUM LTD UK (OXFORD) coordinator 3˙460˙486.00

Map

 Project objective

Chronic liver diseases are called 'silent killers', as clinical symptoms only surface at late stages of the disease, when it is not treatable. Non-alcoholic fatty liver disease (NAFLD), a condition defined by fat accumulation in the liver, and its sub-type non-alcoholic steatohepatitis (NASH) are the major forms of liver disease. Untreated NAFLD/NASH can lead to cirrhosis and to liver failure. 450 million people worldwide suffer from fatty liver disease, which carries several health risks, and causes a huge socio-economic burden. At present, the only way of diagnosing and staging disease is with liver biopsy, which is costly, invasive, and carries some risk. Thus, clinicians are reluctant to use it for people suspected of having NAFLD/NASH. In addition, invasive biopsy is not optimal for serial assessment (e.g. monitoring transplant population for signs of liver rejection). Therefore, there is a lack of an accurate and non-invasive method of assessing liver disease and enabling treatment monitoring. Perspectum Diagnostics Ltd (PD) has developed LiverMultiScan, a novel, non-invasive, quantitative Magnetic Resonance Imaging software tool that displays high diagnostic accuracy for the early assessment of liver disease, and can be used for patient stratification. It has recently obtained regulatory clearance, but it requires additional clinical validation to assure its broad market acceptance and reimbursement. Thus, RADIcAL entails two clinical trials: a) a multi-centre randomised health economic study to validate the cost-effectiveness and added value of LiverMultiScan compared to the standard care pathway for chronic liver disease; and (b) a prospective clinical trial to demonstrate the high sensitivity and specificity of LiverMultiScan as a medical support tool for stratifying patients at high risk of liver transplant rejection.

 Deliverables

List of deliverables.
SOP for data protection Documents, reports 2020-03-11 15:04:46
Data management plan Documents, reports 2020-03-11 15:04:46
Communication plan and updates Documents, reports 2020-03-11 15:04:46

Take a look to the deliverables list in detail:  detailed list of RADIcAL deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "RADICAL" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "RADICAL" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.2.1.3.;H2020-EU.3.1.3.)

PNEUMOSIP (2015)

PNEUMOSIP

Read More  

OncoMasTR (2016)

OncoMasTR - Novel Prognostic Assay for Early Stage Breast Cancer

Read More  

Respiratory-ImmunoDx (2015)

Clinical validation of host biomarker signature for distinguishing bacterial versus viral lower respiratory tract infections (LRTI) in adults at the point-of-need

Read More