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FETAL MONITORING

Safe and accurate fetal monitoring

Total Cost €

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EC-Contrib. €

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Partnership

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Project "FETAL MONITORING" data sheet

The following table provides information about the project.

Coordinator
NEMO HEALTHCARE BV 

Organization address
address: DE RUN 4630
city: VELDHOVEN
postcode: 5504 DB
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://www.nemohealthcare.com/nl/h2020
 Total cost 4˙054˙000 €
 EC max contribution 4˙054˙000 € (100%)
 Programme 1. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
2. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2015
 Funding Scheme SME-2
 Starting year 2016
 Duration (year-month-day) from 2016-07-01   to  2018-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NEMO HEALTHCARE BV NL (VELDHOVEN) coordinator 4˙054˙000.00

Map

 Project objective

During gestation and birth, problems are encountered in up to 15% of all births. Most problems are related to fetal hypoxia and preterm birth. It is estimated that every year over 30.000 babies in Europe suffer from birth asphyxia, despite the common use of monitoring. Recent Norwegian research (2013) revealed inadequate fetal monitoring is responsible for 50% of the cases where human error caused birth asphyxia (oxygen deficiency). It can be concluded that current monitoring technology does not detect vital information on fetal wellbeing, causing unnecessary risks which can eventually lead to fetal mortality. There is thus a clear market need for fetal monitoring technology that is accurate, safe (non-invasive) and easy to use. Nemo Healthcare, a high-tech startup company, is responding to this market need through the development of an innovative electrode patch and hardware/software module that can simultaneously record uterine activity and fetal heart rate. The solution of Nemo is characterized by unique and smart algorithms that can accurately and real-time filter contractions and the fetal heart rate from unprocessed abdominal electrophysiological signals, successfully eliminating noise or interference. The solution will be able to transfer the recorded data wirelessly. The solution will create a breakthrough in the field of fetal monitoring: it will result in better diagnoses, improved quality of care, a reduced number of birth-related problems, increased user friendliness (for medical staff as well as the patient) and lower healthcare cost (through remote monitoring, reduced treatment and avoidance of unnecessary surgery).

 Deliverables

List of deliverables.
CE- approval (M20), FDA clearance Other 2019-05-31 18:17:57
(Online)dissemination material Websites, patent fillings, videos etc. 2019-05-31 18:18:03
Project website Websites, patent fillings, videos etc. 2019-05-31 18:17:59
Ethical committee approval Other 2019-05-31 18:17:55

Take a look to the deliverables list in detail:  detailed list of FETAL MONITORING deliverables.

 Publications

year authors and title journal last update
List of publications.
2017 G. J. J. Warmerdam, R. Vullings, L. Schmitt, J. O. E. H. Van Laar, J. W. M. Bergmans
A Fixed-Lag Kalman Smoother to Filter Power Line Interference in Electrocardiogram Recordings
published pages: 1852-1861, ISSN: 0018-9294, DOI: 10.1109/TBME.2016.2626519
IEEE Transactions on Biomedical Engineering 64/8 2019-06-13
2017 Marion W.C. Vlemminx, Kirsten M.J. Thijssen, Galin I. Bajlekov, Jeanne P. Dieleman, M. Beatrijs Van Der Hout-Van Der Jagt, S. Guid Oei
Electrohysterography for uterine monitoring during term labour compared to external tocodynamometry and intra-uterine pressure catheter
published pages: 197-205, ISSN: 0301-2115, DOI: 10.1016/j.ejogrb.2017.05.027
European Journal of Obstetrics & Gynecology and Reproductive Biology 215 2019-06-13
2016 Kim M. J. Verdurmen, Carlijn Lempersz, Rik Vullings, Christian Schroer, Tammo Delhaas, Judith O. E. H. van Laar, S. Guid Oei
Normal ranges for fetal electrocardiogram values for the healthy fetus of 18–24 weeks of gestation: a prospective cohort study
published pages: , ISSN: 1471-2393, DOI: 10.1186/s12884-016-1021-x
BMC Pregnancy and Childbirth 16/1 2019-06-13
2016 Kim M.J. Verdurmen, Alexandra D.J. Hulsenboom, Judith O.E.H. van Laar, Pieter F.F. Wijn, Rik Vullings, S. Guid Oei
Orientation of the electrical heart axis in mid-term pregnancy
published pages: 243-246, ISSN: 0301-2115, DOI: 10.1016/j.ejogrb.2016.10.030
European Journal of Obstetrics & Gynecology and Reproductive Biology 207 2019-06-13
2018 G J J Warmerdam, R Vullings, J O E H Van Laar, M B Van der Hout-Van der Jagt, J W M Bergmans, L Schmitt, S G Oei
Detection rate of fetal distress using contraction-dependent fetal heart rate variability analysis
published pages: 25008, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aaa925
Physiological Measurement 39/2 2019-06-13
2017 Vlemminx M, Thijssen K, Van der Hout- van der Jagt B, Oei G
Uterine monitoring in morbidly obese parturients by electrohysterography
published pages: 62, ISSN: , DOI:
ECIC 2017 (3rd European Congress on Intrapartum Care) - Abstract Book No 3. Frequency: every two year 2019-06-13
2017 I. Roest, M.M. Goorts, C. Lempersz, R. Vullings, M.E.M.H. Westerhuis, S.G. Oei
Foetale monitoring middels het niet-invasieve foetale ECG: een demonstratie van verschillende casus
published pages: 12-15, ISSN: 0923-4667, DOI:
Medisch Journaal Vol. 46, issue 2, 2017 2019-06-13
2016 S.B. Clur, D. Aben, M. Sengers, G. Oei, J. van der Post, N.A. Blom, C. Lempersz, J. van Laar, R. Vullings
Prelabour fetal ECG in congenital heart disease – a preliminary comparison with neonatal ECG
published pages: 247, ISSN: , DOI: 10.1002/uog.16737
Ultrasound in Obstetrics & Gynecology Volume 48, Issue Supplement S1 2019-06-13
2018 Marion W. C. Vlemminx, Kirsten M. J. Thijssen, Galin I. Bajlekov, Jeanne P. Dieleman, M. Beatrijs Van Der Hout-Van Der Jagt, S. Guid Oei
Could electrohysterography be the solution for external uterine monitoring in obese women?
published pages: 580-586, ISSN: 0743-8346, DOI: 10.1038/s41372-018-0065-3
Journal of Perinatology 38/5 2019-06-13
2017 Rik Vullings, Kim M. J. Verdurmen, Alexandra D. J. Hulsenboom, Stephanie Scheffer, Hinke de Lau, Anneke Kwee, Pieter F. F. Wijn, Isis Amer-WÃ¥hlin, Judith O. E. H. van Laar, S. Guid Oei
The electrical heart axis and ST events in fetal monitoring: A post-hoc analysis following a multicentre randomised controlled trial
published pages: e0175823, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0175823
PLOS ONE 12/4 2019-06-13
2017 M.M. Goorts, C. Lempersz, R. Vullings, M.E.M.H. Westerhuis, S.G. Oei
Clinical application of non-invasive fetal ECG monitoring to obtain CTG during pregnancy
published pages: 173, ISSN: , DOI:
ECIC 2017 (3rd European Congress on Intrapartum Care) - Abstract Book No 3. Frequency: every two year 2019-06-13
2017 K. Verdurmen, G. Warmerdam, C. Lempersz, A. Hulsenboom, J. Dieleman, R. Vullings, J. van Laar, S. Oei
The influence of betamethasone on fetal heart rate variability, obtained by non-invasive fetal electrocardiogram recordings
published pages: 44, ISSN: , DOI:
ECIC 2017 (3rd European Congress on Intrapartum Care) - Abstract Book No 3. Frequency: every two year 2019-06-13
2017 I. Roest, C. Lempersz, R. Vullings, M.E.M.H. Westerhuis, S.G. Oei
Clinical application of non-invasive fetal ECG monitoring during labour
published pages: 31, ISSN: , DOI:
ECIC 2017 (3rd European Congress on Intrapartum Care) - Abstract Book No 3. Frequency: every two year 2019-06-13
2018 Guy J. J. Warmerdam, Rik Vullings, Lars Schmitt, Judith O. E. H. Van Laar, Jan W. M. Bergmans
Hierarchical Probabilistic Framework for Fetal R-Peak Detection, Using ECG Waveform and Heart Rate Information
published pages: 4388-4397, ISSN: 1053-587X, DOI: 10.1109/TSP.2018.2853144
IEEE Transactions on Signal Processing 66/16 2019-04-04
2018 E. Fotiadou, J. O. E. H. van Laar, S. G. Oei, R. Vullings
Enhancement of low-quality fetal electrocardiogram based on time-sequenced adaptive filtering
published pages: pp 1-11, ISSN: 0140-0118, DOI: 10.1007/s11517-018-1862-8
Medical & Biological Engineering & Computing 25 June 2018 2019-04-04
2018 Marion Vlemminx, Michelle Westerhuis, Jeanne Dieleman, M. Beatrijs Van der Hout-Van der Jagt, S. Guid Oei, Kirsten Thijssen
Uterine Monitoring Techniques from Patients\' and Users\' Perspectives
published pages: e184-e191, ISSN: 2157-6998, DOI: 10.1055/s-0038-1669409
American Journal of Perinatology Reports 08/03 2019-04-04
2018 Kim M.J. Verdurmen, Guy J.J. Warmerdam, Carlijn Lempersz, Alexandra D.J. Hulsenboom, Joris Renckens, Jeanne P. Dieleman, Rik Vullings, Judith O.E.H. van Laar, S. Guid Oei
The influence of betamethasone on fetal heart rate variability, obtained by non-invasive fetal electrocardiogram recordings
published pages: 8-14, ISSN: 0378-3782, DOI: 10.1016/j.earlhumdev.2018.02.011
Early Human Development 119 2019-04-04

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