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Clinical performance validation of a novel biomarker for quantitative imaging of coronary artery disease.

Total Cost €


EC-Contrib. €






 MPIPETrace project word cloud

Explore the words cloud of the MPIPETrace project. It provides you a very rough idea of what is the project "MPIPETrace" about.

emission    imaging    dmdpa    rates    unnecessary    offers    risk    11c    myocardial    events    serve    willingness    possibility    tomography    commercialize    biomarker    discovery    partnering    stakeholders    reserve    compelling    radiation    doses    invasive    globally    cardiovascular    indicate    coronary    downstream    attack    disease    probes    trend    toxicity    quality    advantages    feasibility    heart    quantifying    agents    marker    tests    nuclear    risks    abundance    trials    consultancy    projected    spect    efficient    absolute    period    business    clinical    players    mpi    shortage    evaluation    superior    market    pay    shorter    measuring    scanners    outnumber    artery    adoption    flow    confirmed    adverse    pet    retention    deals    image    prognostic    opportunity    patients    western    positron    negotiations    predict    volume    world    2020    cad    blood    death    perfusion    publications    motivated    economic    form    cardiac    diagnostic    synthesis   

Project "MPIPETrace" data sheet

The following table provides information about the project.


Organization address
address: AL. WITOSA 31
postcode: 00-710
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Poland [PL]
 Project website
 Total cost 3˙687˙250 €
 EC max contribution 3˙687˙250 € (100%)
 Programme 1. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
2. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2015
 Funding Scheme SME-2
 Starting year 2015
 Duration (year-month-day) from 2015-10-01   to  2019-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SYNEKTIK SPOLKA AKCYJNA PL (WARSZAWA) coordinator 3˙687˙250.00


 Project objective

Coronary Artery Disease (CAD) is the most common form of heart disease and is the leading cause of death in Europe and the Western World. Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) offers the unique possibility of measuring and quantifying myocardial blood flow and coronary flow reserve in absolute terms, which serve as a prognostic marker for adverse cardiac events: It can predict the risk of heart attack. PET also offers advantages such as: superior image quality and diagnostic ability, reduction of unnecessary invasive downstream procedures and reduction of patients’ risks due to reduced radiation doses and shorter period of radiation retention. Currently, there is a shortage of available, simple and efficient PET myocardial perfusion imaging agents. Motivated by the growing business opportunity in PET cardiac imaging and the success of completed synthesis and evaluation discovery process, as well as pre-clinical trials and toxicity tests, the objective of this project is Phase 1 and 2 clinical trials of the novel biomarker [11C]-DMDPA for Myocardial Perfusion Imaging using Positron Emission Tomography, and to commercialize it globally. The adoption of Positron Emission Tomography for Myocardial Perfusion Imaging will occur as a result of numerous advantages and the growing abundance and availability of PET scanners in recent and future years. There is compelling evidence that our novel biomarker is addressing a high growth trend in a high volume market of the cardiovascular disease nuclear imaging, and specifically the growing need of non-invasive PET cardiac probes. According to publications, the projected growth rates indicate that PET will outnumber SPECT cardiac procedures by 2020. The willingness to pay has been confirmed during our economic feasibility assessment of the project, by means of consultancy with key stakeholders and negotiations with a number of key players on Diagnostic Partnering deals.

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The information about "MPIPETRACE" are provided by the European Opendata Portal: CORDIS opendata.

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