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EU-GliaPhD SIGNED

Training, Research and Raising of Public Awareness in Cell Biology and Pathology of Neuroglia

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EU-GliaPhD" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT DES SAARLANDES 

Organization address
address: CAMPUS
city: SAARBRUCKEN
postcode: 66123
website: www.uni-saarland.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.eu-gliaphd.eu/
 Total cost 3˙924˙324 €
 EC max contribution 3˙924˙324 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-12-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT DES SAARLANDES DE (SAARBRUCKEN) coordinator 498˙432.00
2    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 516˙122.00
3    UNIVERSITATSKLINIKUM BONN DE (BONN) participant 498˙432.00
4    H. LUNDBECK AS DK (VALBY) participant 290˙081.00
5    OSLO UNIVERSITETSSYKEHUS HF NO (OSLO) participant 286˙275.00
6    ASTON UNIVERSITY UK (BIRMINGHAM) participant 273˙287.00
7    CARDIFF UNIVERSITY UK (CARDIFF) participant 273˙287.00
8    COLLEGE DE FRANCE FR (PARIS) participant 262˙875.00
9    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 262˙875.00
10    FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA IT (MILANO) participant 258˙061.00
11    AMC MEDICAL RESEARCH BV NL (AMSTERDAM ZUIDOOST) participant 255˙374.00
12    NPI ELECTRONIC GESELLSCHAFT FUER MESS- UND REGELSYSTEME MBH DE (TAMM) participant 249˙216.00
13    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 0.00
14    CARL ZEISS MICROSCOPY GMBH DE (Jena) partner 0.00
15    Epilepsy Action (British Epilepsy Association) UK (Yeadon) partner 0.00
16    EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH DE (ST INGBERT) partner 0.00
17    FORMICABLU SRL IT (BOLOGNA) partner 0.00

Map

 Project objective

The research in which the young scientists of the EU-GliaPhD consortium will be trained is centred on the role of neuron-glia interactions in brain function and pathology. Prompted by exciting discoveries of recent years, many academic research groups are currently focussing their research on the field of neuron-glia interactions for a better understanding of brain function. Also the private sector such as the pharmaceutical industry pays more and more attention to the role of neuroglia in various neuropathologies. These research activities create an increasing demand for outstanding young neuroscientists to join academia or industry. To address this need for neuroscientists with a strong knowledge in neuron-glia interactions, the EU-GliaPhD consortium of recognized European neuroscientists decided to initiate a training network in which young scientists, the EU-GliaPhD fellows will be educated in collaborative research projects to study neuron-glia interactions at the molecular, cellular and systems level in the healthy and the diseased brain. A strong emphasis will lie on epilepsy, a multi-faceted, chronic neurological disorder characterized by the frequent recurrence of seizures. The EU-GliaPhD consortium will focus on five important educational and training objectives: 1. Broad training in several current state-of-art technologies that are highly relevant for brain research 2. Teaching an in-depth understanding of molecular and cellular neurobiology and -pathology 3. Focused specialization in defined research projects 4. Training in dissemination of modern neuroscience research to expert and lay audiences 5. Education in soft skills such as article writing, oral presentations or research ethics By studying epilepsy, fundamental questions on the cellular and molecular aspects of neuron-glia interaction can be addressed. Novel insight delivered by EU-GliaPhD may serve as basis for the development of novel strategies in treating brain disorders.

 Deliverables

List of deliverables.
Internet blog together with patients’ organisation Websites, patent fillings, videos etc. 2019-06-27 15:43:38
EU-GliaPhD project website Websites, patent fillings, videos etc. 2019-06-27 15:43:38

Take a look to the deliverables list in detail:  detailed list of EU-GliaPhD deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letizia Mariotti, Gabriele Losi, Annamaria Lia, Marcello Melone, Angela Chiavegato, Marta Gómez-Gonzalo, Michele Sessolo, Serena Bovetti, Angelo Forli, Micaela Zonta, Linda Maria Requie, Iacopo Marcon, Arianna Pugliese, Cécile Viollet, Bernhard Bettler, Tommaso Fellin, Fiorenzo Conti, Giorgio Carmignoto
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes
published pages: 82, ISSN: 2041-1723, DOI: 10.1038/s41467-017-02642-6
Nature Communications 9/1 2019-06-27
2018 Glenn Dallérac, Jonathan Zapata, Nathalie Rouach
Versatile control of synaptic circuits by astrocytes: where, when and how?
published pages: 729-743, ISSN: 1471-003X, DOI: 10.1038/s41583-018-0080-6
Nature Reviews Neuroscience 19/12 2019-06-27
2018 Ljiljana Nikolic, Weida Shen, Paola Nobili, Anaïs Virenque, Lauriane Ulmann, Etienne Audinat
Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis
published pages: 2673-2683, ISSN: 0894-1491, DOI: 10.1002/glia.23519
Glia 66/12 2019-06-27
2018 Jackelien van Scheppingen, James D. Mills, Till S. Zimmer, Diede W.M. Broekaart, Valentina Iori, Anika Bongaarts, Jasper J. Anink, Anand M. Iyer, Anatoly Korotkov, Floor E. Jansen, Wim van Hecke, Wim G. Spliet, Peter C. van Rijen, Johannes C. Baayen, Annamaria Vezzani, Erwin A. van Vliet, Eleonora Aronica
miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes
published pages: 1082-1097, ISSN: 0894-1491, DOI: 10.1002/glia.23302
Glia 66/5 2019-06-27
2018 Hannah M. Jahn, Carmen V. Kasakow, Andreas Helfer, Julian Michely, Alexei Verkhratsky, Hans H. Maurer, Anja Scheller, Frank Kirchhoff
Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia
published pages: 5913, ISSN: 2045-2322, DOI: 10.1038/s41598-018-24085-9
Scientific Reports 8/1 2019-06-27
2018 Andrea Arena, Till S. Zimmer, Jackelien van Scheppingen, Anatoly Korotkov, Jasper J. Anink, Angelika Mühlebner, Floor E. Jansen, Wim van Hecke, Wim G. Spliet, Peter C. van Rijen, Annamaria Vezzani, Johannes C. Baayen, Sander Idema, Anand M. Iyer, Marzia Perluigi, James D. Mills, Erwin A. van Vliet, Eleonora Aronica
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence
published pages: , ISSN: 1015-6305, DOI: 10.1111/bpa.12661
Brain Pathology 2019-06-27
2018 Pavel Klein, Raymond Dingledine, Eleonora Aronica, Christophe Bernard, Ingmar Blümcke, Detlev Boison, Martin J. Brodie, Amy R. Brooks-Kayal, Jerome Engel, Patrick A. Forcelli, Lawrence J. Hirsch, Rafal M. Kaminski, Henrik Klitgaard, Katja Kobow, Daniel H. Lowenstein, Phillip L. Pearl, Asla Pitkänen, Noora Puhakka, Michael A. Rogawski, Dieter Schmidt, Matti Sillanpää, Robert S. Sloviter, Christian Steinhäuser, Annamaria Vezzani, Matthew C. Walker, Wolfgang Löscher
Commonalities in epileptogenic processes from different acute brain insults: Do they translate?
published pages: 37-66, ISSN: 0013-9580, DOI: 10.1111/epi.13965
Epilepsia 59/1 2019-06-27
2017 James D. Mills, Anand M. Iyer, Jackelien van Scheppingen, Anika Bongaarts, Jasper J. Anink, Bart Janssen, Till S. Zimmer, Wim G. Spliet, Peter C. van Rijen, Floor E. Jansen, Martha Feucht, Johannes A. Hainfellner, Pavel Krsek, Josef Zamecnik, Katarzyna Kotulska, Sergiusz Jozwiak, Anna Jansen, Lieven Lagae, Paolo Curatolo, David J. Kwiatkowski, R. Jeroen Pasterkamp, Ketharini Senthilkumar, Lars von Oerthel, Marco F. Hoekman, Jan A. Gorter, Peter B. Crino, Angelika Mühlebner, Brendon P. Scicluna, Eleonora Aronica
Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment
published pages: 8089, ISSN: 2045-2322, DOI: 10.1038/s41598-017-06145-8
Scientific Reports 7/1 2019-06-27
2018 Cian McCafferty, François David, Marcello Venzi, Magor L. Lőrincz, Francis Delicata, Zoe Atherton, Gregorio Recchia, Gergely Orban, Régis C. Lambert, Giuseppe Di Giovanni, Nathalie Leresche, Vincenzo Crunelli
Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures
published pages: 744-756, ISSN: 1097-6256, DOI: 10.1038/s41593-018-0130-4
Nature Neuroscience 21/5 2019-06-27
2017 A. Korotkov, J. D. Mills, J. A. Gorter, E. A. van Vliet, E. Aronica
Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy
published pages: 11592, ISSN: 2045-2322, DOI: 10.1038/s41598-017-11510-8
Scientific Reports 7/1 2019-06-27
2018 Christine R. Rose, Lisa Felix, Andre Zeug, Dirk Dietrich, Andreas Reiner, Christian Henneberger
Astroglial Glutamate Signaling and Uptake in the Hippocampus
published pages: 451, ISSN: 1662-5099, DOI: 10.3389/fnmol.2017.00451
Frontiers in Molecular Neuroscience 10 2019-06-27
2018 Leonid P. Savtchenko, Lucie Bard, Thomas P. Jensen, James P. Reynolds, Igor Kraev, Nikolay Medvedev, Michael G. Stewart, Christian Henneberger, Dmitri A. Rusakov
Disentangling astroglial physiology with a realistic cell model in silico
published pages: 3554, ISSN: 2041-1723, DOI: 10.1038/s41467-018-05896-w
Nature Communications 9/1 2019-06-27

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