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EN_ACTI2NG SIGNED

European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EN_ACTI2NG" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 2˙539˙859 €
 EC max contribution 2˙539˙859 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme /MSCA-ITN-ETN
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 247˙872.00
2    UNIVERSITY OF BRISTOL UK (BRISTOL) participant 273˙287.00
3    MEDIZINISCHE UNIVERSITAET WIEN AT (WIEN) participant 255˙934.00
4    STRATEC CONSUMABLES GMBH AT (ANIF) participant 255˙934.00
5    TECHNISCHE UNIVERSITAET WIEN AT (WIEN) participant 255˙934.00
6    ACADEMISCH ZIEKENHUIS LEIDEN NL (LEIDEN) participant 255˙374.00
7    ALBERT-LUDWIGS-UNIVERSITAET FREIBURG DE (FREIBURG) participant 249˙216.00
8    KLINIKUM DER UNIVERSITAET ZU KOELN DE (KOELN) participant 249˙216.00
9    UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT DE (WURZBURG) participant 249˙216.00
10    FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA ES (PAMPLONA) participant 247˙872.00
11    CELLULAR THERAPEUTICS LIMITED UK (WILMSLOW) partner 0.00
12    SCIENSEED SL ES (MADRID) partner 0.00

Mappa

 Project objective

The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors and to improve efficiency and on- and off-target toxicity are current challenges Therefore the EN-ACTI2NG program aims 1) to train PhD students with expertise in development of new and improved T cell-mediated cancer immuno-therapies; 2) to endow the PhD students with the ability to establish efficient communication between the academic and industrial research environments and between scientists and the general public; 3) to improve T cell mediated anti-cancer immuno-therapy by the identification and development of new cancer-specific immune receptors and enhancing their function by identifying and modifying their molecular mechanism of action. To reach these objectives we have designed individual research projects ranging from biophysical analysis of immune receptors, via molecular modification of their structure and testing their tumor killing capacity in cell-based and pre-clinical assays to product development. Secondments will assure that each PhD student will be exposed to these complementary approaches and that there will be synergic feedback between the projects, producing innovative results that could otherwise not be achieved. Extensive training in research-specific skills, career development and a continuous training in communication skills will allow the PhD students to become facilitators of the process of transformation of scientific innovation into products with social and economic value. As such, the EN-ACTI2NG program should contribute to overcoming the more general challenge of converting the European Community into an innovation-driven society.

 Work performed, outcomes and results:  advancements report(s) 

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The information about "EN_ACTI2NG" are provided by the European Opendata Portal: CORDIS opendata.

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