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CENSUS SIGNED

Cell-Based Models for Neurodegeneration Study and Use in Screening

Total Cost €

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EC-Contrib. €

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Partnership

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 CENSUS project word cloud

Explore the words cloud of the CENSUS project. It provides you a very rough idea of what is the project "CENSUS" about.

healthcare    convenience    multiwell    simpler    lineages    drug    disciplinary    pluripotent    printer    cells    skillset    kits    unsustainable    science    ready    click    predictive    care    combinations    dendrons    stem    trl    burden    manufacture    additive    models    treatment    shown    cryopreservation       unprecedented    uk    cell    reinstate    familiar    tissue    assembled    inks    single    comprising    tools    printable    culture    delivered    neurodegenerative    first    biomaterials    realised    clinical    generate    differentiation    scaffolds    output    made    countries    protocols    phenocell    plates    global    glial    unmet    census    co    inclusion    patient    inter    sarl    instrumentation    3d    manufacturing    cryopreserved    ltd    se    human    situ    combination    chemistry    proprietary    utility    disease    phenotypes    innovative    supplying    biological    discovery    precision    containing    neuronal    market    sme    validated    toolset    ipsc    advantage    customised    bio    analytical    outputs    avanticell    commercial    industrial    assembles    exceptional    formats    mature    cellink    contributed    neural    donor    peptide    biology    screening   

Project "CENSUS" data sheet

The following table provides information about the project.

Coordinator
AvantiCell Science Ltd 

Organization address
address: GIBBSYARD BUILDING
city: AYR
postcode: KA6 5HW
website: www.avanticell.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.avanticell.com/technologies/projects/census
 Total cost 2˙561˙828 €
 EC max contribution 1˙793˙280 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2. (PRIORITY 'Industrial leadership')
 Code Call H2020-FTIPilot-2016-1
 Funding Scheme IA
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2019-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AvantiCell Science Ltd UK (AYR) coordinator 675˙736.00
2    CELLINK AB SE (GOTEBORG) participant 452˙943.00
3    PHENOCELL FR (GRASSE) participant 410˙850.00
4    TISSUE CLICK LTD UK (BRIGHTON) participant 253˙750.00

Map

 Project objective

1. Treatment of neurodegenerative disease is an unmet clinical challenge and patient care is a growing, unsustainable global healthcare burden. The project will produce novel tools to address this challenge. 2. The consortium will deliver a set of innovative analytical tools for neurodegenerative drug discovery using a combination of stem cell biology and novel biomaterials assembled by additive manufacturing. 3. The toolset will be analytical kits containing induced pluripotent stem cell (iPSC)-derived human neural cells in 3D culture formats, delivered to end-users in multiwell plates ready for industrial screening. 4. Project outputs will be realised by an inter-disciplinary consortium of four SME commercial partners in three European countries, each partner supplying a specific, essential skillset. 5. iPSC-derived neural cells will be produced by Phenocell sarl (F) using stem cell differentiation protocols already shown to generate glial or neuronal cell lineages, and to reinstate donor disease phenotypes. 6. Bio-printer instrumentation and printable bio-inks to manufacture 3D scaffolds enabling 3D cell culture will be contributed by Cellink (SE). 7. 3D culture models will be customised for neural/neurodegenerative cell culture by inclusion of peptide dendrons with biological functionality using mature chemistry proprietary to Tissue Click Ltd (UK). 8. Cell-based analysis products will be validated, and made user-friendly by in situ cell cryopreservation and analytical processes familiar to AvantiCell Science Ltd (UK). 9. Each contributing technology is at TRL 6, and each has commercial utility in simpler combinations. The project assembles them in first-to-market formats beyond the current state of the art. 10. The CENSUS project output, comprising iPSC-derived neural cells cryopreserved in single-cell and co-culture 3D formats will deliver exceptional analytical precision and predictive value, unprecedented end-user convenience and strong commercial advantage

 Deliverables

List of deliverables.
Documents defining technical performance and applications of 3D printed cell models Documents, reports 2020-03-27 10:43:50
CNS cell product and product information for dual cell-type model Demonstrators, pilots, prototypes 2020-03-27 10:43:50
CNS cell product and product information for single cell-type model Demonstrators, pilots, prototypes 2020-03-27 10:43:50

Take a look to the deliverables list in detail:  detailed list of CENSUS deliverables.

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The information about "CENSUS" are provided by the European Opendata Portal: CORDIS opendata.

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