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EVOMICROCOMM SIGNED

Evolving interactions in microbial communities

Total Cost €

EC-Contrib. €

Partnership

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EVOMICROCOMM project word cloud

Explore the words cloud of the EVOMICROCOMM project. It provides you a very rough idea of what is the project "EVOMICROCOMM" about.

ultimate biofuels evolve customised bacterial scratch experimental generate degrade evolution stability couple interact microbes social avenues foundations community disentangle characterise species live create functioning living pollutants intestinal habitats members pollution treatments health model lives cells breed conceptual efficient toward purposes degradation alters involve promises cooperative generally microbial possess directing experiments interdisciplinary waste communities almost natural thereby vision tools dense ecosystems play theory strains interactions productivity ecosystem first diseases theoretical environment

Project "EVOMICROCOMM" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE DE LAUSANNE Organization address address: Quartier Unil-Centre Bâtiment Unicentre city: LAUSANNE postcode: 1015 website: www.unil.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Switzerland [CH]
Total cost	1˙498˙875 €
EC max contribution	1˙498˙875 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2016-STG
Funding Scheme	ERC-STG
Starting year	2017
Duration (year-month-day)	from 2017-05-01 to 2022-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE DE LAUSANNE UNIVERSITE DE LAUSANNE Organization address address: Quartier Unil-Centre Bâtiment Unicentre city: LAUSANNE postcode: 1015 website: www.unil.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (LAUSANNE)	coordinator	1˙498˙875.00

Map

Project objective

Microbes play an important role in various aspects of our lives, from our own health to the health of our environment. In almost all of their natural habitats, microbes live in dense communities composed of different strains and species that interact with each other. As these microbes evolve, so do the interactions between them, which alters the functioning of the community as a whole.

In this project, I propose to develop theoretical and experimental tools to study and control evolving interactions between cells and species living in microbial ecosystems. This will involve three main research objectives: first, we will couple theory and experiments to disentangle and characterise the social interactions between five bacterial species that make up an ecosystem used to degrade pollutants. Our second objective will be to use this knowledge to control this same ecosystem, by directing it toward increased productivity and stability. Finally, our third objective will be to “breed” novel communities from scratch using experimental evolution to promote cooperative interactions between community members and thereby increase productivity.

This interdisciplinary and ambitious research will allow us to improve existing methods in pollution degradation, and to design new microbial communities for this and other purposes. More generally, our model system will provide an in-depth conceptual understanding of microbial ecosystems and their evolution, and the tools to investigate more complex microbial communities. My ultimate vision is to possess the technology to use microbial communities to degrade waste, generate efficient biofuels, and design customised treatments for intestinal diseases. This project promises to create the foundations needed to develop this technology, and open many exciting avenues for future research.

Publications

List of publications.
year	authors and title	journal	last update
2019	Shota Shibasaki, Sara Mitri Controlling evolutionary dynamics to optimize microbial bioremediation published pages: , ISSN: , DOI: 10.1101/705749	bioRxiv pre-print server	2020-02-04
2019	Philippe Piccardi, BjÃ¶rn Vessman, Sara Mitri Toxicity drives facilitation between 4 bacterial species published pages: 15979-15984, ISSN: 0027-8424, DOI: 10.1073/pnas.1906172116	Proceedings of the National Academy of Sciences 116/32	2020-01-28
2019	Flor I. Arias-SÃ¡nchez, BjÃ¶rn Vessman, Sara Mitri Artificially selecting microbial communities: If we can breed dogs, why not microbiomes? published pages: e3000356, ISSN: 1545-7885, DOI: 10.1371/journal.pbio.3000356	PLOS Biology 17/8	2020-01-30
2019	Samuele Testa, Sarah Berger, Philippe Piccardi, Frank Oechslin, GrÃ©gory Resch, Sara Mitri Spatial structure affects phage efficacy in infecting dual-strain biofilms of Pseudomonas aeruginosa published pages: , ISSN: 2399-3642, DOI: 10.1038/s42003-019-0633-x	Communications Biology 2/1	2020-01-28

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