NinZA
Theranostic molecular zipper based switchable nanomedicine for overcoming drug resistance
Total Cost €
0EC-Contrib. €
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Project "NinZA" data sheet
The following table provides information about the project.
| Coordinator |
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Organization address contact info |
| Coordinator Country | United Kingdom [UK] |
| Project website | https://www.ceb.cam.ac.uk/directory/hirak-patra |
| Total cost | 195˙454 € |
| EC max contribution | 195˙454 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2015 |
| Funding Scheme | MSCA-IF-EF-ST |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-04-15 to 2019-04-14 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE | UK (CAMBRIDGE) | coordinator | 195˙454.00 |
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Project objective
This Fellowship will bring an outstanding researcher from Sweden to the UK to gain new scientific and career skills to position him to become a leading independent academic in the interface of chemistry and biology for translational Nanomedicine. The fellow will design a new class of biomimetic zipper nano-architecture, combining an MRI-enabled SPION scaffold with a zip-unzip, temperature and pH-responsive multi-arm polymer to defuse drug resistant cell functions. These approach could greatly benefit the current investigation of new and alternate therapeutic procedures to overcome drug resistance. The fellow will gain advanced training in translational designs of drugs for recognition and treatment of drug resistant system, and in state of the art techniques for studying such system. Combined with the fellow's knowledge of nanoparticles in medicine, he will have a formidable skill set suited to designing nano-architectures for developing target-specific nano-drugs to push back frontiers in the battle against cancer. His excellent track record is in consistent with last two years performance with 4 publications (with cumulative IF>28) with leading publishers including Nature group, Wiley, Cell press etc., 1 cover page and cover story, one Keynote lecture and 2 international research competition awards (FEBS Young scientist forum and Nano Today, Elsevier ST award). A series of complementary career skills trainings will enhance the fellow's research management, leadership, presentation and teaching skills and make him an impressive and exciting candidate for an independent EU academic position.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Souvik K. Bandyopadhyay, Mohammad Azharuddin, Anjan K. Dasgupta, Bhaswati Ganguli, Sugata SenRoy, Hirak K. Patra, Suryyani Deb Probing ADP Induced Aggregation Kinetics During Platelet-Nanoparticle Interactions: Functional Dynamics Analysis to Rationalize Safety and Benefits published pages: , ISSN: 2296-4185, DOI: 10.3389/fbioe.2019.00163 |
Frontiers in Bioengineering and Biotechnology 7 | 2019-10-15 |
| 2018 |
Arka Mukhopadhyay, Sankar Basu, Santiswarup Singha, Hirak K. Patra Inner-View of Nanomaterial Incited Protein Conformational Changes: Insights into Designable Interaction published pages: 1-15, ISSN: 2639-5274, DOI: 10.1155/2018/9712832 |
Research 2018 | 2019-10-15 |
| 2019 |
Debarshi Banerjee, Artur Cieslar-Pobuda, Geyunjian Harry Zhu, Emilia Wiechec, Hirak K. Patra Adding Nanotechnology to the Metastasis Treatment Arsenal published pages: 403-418, ISSN: 0165-6147, DOI: 10.1016/j.tips.2019.04.002 |
Trends in Pharmacological Sciences 40/6 | 2019-10-15 |
| 2019 |
Hirak K. Patra, Mohammad Azharuddin, Mohammad M. Islam, Georgia Papapavlou, Suryyani Deb, Johannes Osterrieth, Geyunjian Harry Zhu, Thobias Romu, Ashis K. Dhara, Mohammad J. Jafari, Amineh Gadheri, Jorma Hinkula, Madhavan S. Rajan, Nigel K. H. Slater Rational Nanotoolbox with Theranostic Potential for Medicated Proâ€Regenerative Corneal Implants published pages: 1903760, ISSN: 1616-301X, DOI: 10.1002/adfm.201903760 |
Advanced Functional Materials | 2019-10-15 |
| 2019 |
Mohammad Azharuddin, Geyunjian H. Zhu, Debapratim Das, Erdogan Ozgur, Lokman Uzun, Anthony P. F. Turner, Hirak K. Patra A repertoire of biomedical applications of noble metal nanoparticles published pages: , ISSN: 1359-7345, DOI: 10.1039/c9cc01741k |
Chemical Communications | 2019-10-15 |
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