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ChiPyrNMR

Better tools for combating insect borne diseases by understanding influences on the fate of common pesticides in paint formulations

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ChiPyrNMR project word cloud

Explore the words cloud of the ChiPyrNMR project. It provides you a very rough idea of what is the project "ChiPyrNMR" about.

suffer    fate    exists    vaccines    biological    transmitted    degradation    fever    environment    dengue    matrices    safer    clear    extraction    critical    situ    mosquitoes    zika    adjusted    chemical    phenomena    hydrolysis    deployment    centers    avoiding    preparation    collateral    spectroscopy    yellow    mosquito    damage    enantiomers    interaction    behavior    invasive    diseases    malaria    configuration    stability    compounds    individual    health    insecticidal    gained    generate    kinetic    recommended    tools    contact    ingredient    composition    chiral    multidisciplinary    quantifying    laboratory    determined    reduce    humans    exploited    powerful    tracking    formulation    constitutes    risk    paint    occurrence    innovative    formulations    nature    potentially    public    trial    dosing    advantage    once    solutions    enantiomeric    organisation    nmr    protection    little    photo    performed    virus    spread    mechanisms    minimize    prevention    accurately    pyrethroids    either    world    validate    insecticides    significantly    active    insects   

Project "ChiPyrNMR" data sheet

The following table provides information about the project.

Coordinator
NOURYON CHEMICALS B.V. 

Organization address
address: VELPERWEG 76
city: ARNHEM
postcode: 6824 BM
website: www.akzonobel.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 165˙598 €
 EC max contribution 165˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NOURYON CHEMICALS B.V. NL (ARNHEM) coordinator 165˙598.00

Map

 Project objective

Malaria, Zika virus, dengue fever and yellow fever are mosquito transmitted diseases for which a vaccines either do not exists or are not widely available. Prevention control is the main way to reduce their spread, and the use of insecticides constitutes one of the key measures recommended by World Health Organisation. New innovative methods of bringing the insects into contact with the insecticides include the development of insecticidal paint with the advantage of safer application, targeted dosing and significantly reduced risk of collateral damage to humans and the environment. This project will address some of the challenges in developing these solutions. Pyrethroids are one of the best insecticides for public health use but suffer from hydrolysis and photo-degradation. Little is known about how their application in paint formulations affects this behavior. At a chemical level the biological activity of the individual enantiomers is determined by the configuration of their chiral centers, so accurately quantifying the enantiomeric composition is critical to tracking potential degradation. The aim of this project is to generate robust methods for a better understanding of the fate of insecticides in complex matrices like paint. Once the nature of the degradation products and the related mechanisms is clear, the formulation can be adjusted to minimize the occurrence of degradation or enhance active ingredient protection. The kinetic analysis of the degradation processes and the interaction/stability studies are best performed in-situ avoiding potentially invasive extraction sample preparation steps, so the powerful tools of advanced NMR spectroscopy will be exploited to characterize these phenomena. The knowledge gained will be used to validate/explain multidisciplinary laboratory biological trial results on mosquitoes and be able to be exploited more widely to other systems and support the research into other compounds for potential deployment in this way.

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The information about "CHIPYRNMR" are provided by the European Opendata Portal: CORDIS opendata.

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