Explore the words cloud of the SARCOM project. It provides you a very rough idea of what is the project "SARCOM" about.
The following table provides information about the project.
THE UNIVERSITY OF EXETER
|Coordinator Country||United Kingdom [UK]|
|Total cost||183˙454 €|
|EC max contribution||183˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-12-01 to 2019-11-30|
Take a look of project's partnership.
|1||THE UNIVERSITY OF EXETER||UK (EXETER)||coordinator||183˙454.00|
Increased antibiotic resistance (AMR) in a wide range of human pathogens is a growing public health threat, and the World Health Organization (WHO) forecasts a post-antibiotic era for the 21st century (WHO, 2014). The evolution of AMR in bacteria is determined by both the acquisition of resistance through horizontal gene transfer or chromosomal mutation and by the way resistance affects the competitive ability of a microbe in the presence and absence of antibiotics.
The majority of research on selection for AMR to date has focused on detailed in vitro studies of selection for AMR in specific bacterial clones. More significantly, no studies to date have explicitly investigated the implication of being embedded in a complex community for the evolution of AMR. Therefore, in the proposed research I aim to use a multidisciplinary approach by for the first time combining the precision of in vitro experimental evolution experiments with the high resolution of molecular biology to study the evolution and spread of AMR in complex community contexts.
The proposed project will allow me to complement my strong background in molecular biology and microbial ecology with evolutionary microbiology and novel bioinformatic approaches. Being situated in one of the most prominent microbial ecology and evolution laboratories worldwide, based at the Biosciences Department at the University of Exeter will be crucial for my personal development in becoming an independent European researcher. The University of Exeter provides an EU accredited program for academic training and personal career development.
The proposed research will moreover provide ample opportunities to instigate and be involved in internal and international collaboration with world-leading researchers in diverse research fields. Furthermore, I aim to raise public awareness to the threat AMR bacteria possess to human health and involve the public in mitigation strategies to avoid the spread of AMR genes.
|year||authors and title||journal||last update|
Michiel Vos, Louise Sibleyras, Lai Ka Lo, Elze Hesse, William H Gaze, Uli KlÃ¼mper
Zinc can counteract selection for ciprofloxacin resistance
published pages: 780981, ISSN: , DOI:
Maria Arias-Andres, Uli KlÃ¼mper, Keilor Rojas-Jimenez, Hans-Peter Grossart
Microplastic pollution increases gene exchange in aquatic ecosystems
published pages: 253-261, ISSN: 0269-7491, DOI: 10.1016/j.envpol.2018.02.058
|Environmental Pollution 237||2020-02-05|
Uli KlÃ¼mper, Mario Recker, Lihong Zhang, Xiaole Yin, Tong Zhang, Angus Buckling, William H. Gaze
Selection for antimicrobial resistance is reduced when embedded in a natural microbial community
published pages: 2927-2937, ISSN: 1751-7362, DOI: 10.1038/s41396-019-0483-z
|The ISME Journal 13/12||2020-02-05|
Uli KlÃ¼mper, Arnaud Maillard, Elze Hesse, Florian Bayer, Stineke van Houte, Ben Longdon, Will Gaze, Angus Buckling
Short-term evolution under copper stress increases probability of plasmid uptake
published pages: 610873, ISSN: , DOI:
Matthias C. Rillig, Anderson Abel de Souza Machado, Anika Lehmann, Uli KlÃ¼mper
Evolutionary implications of microplastics for soil biota
published pages: 3, ISSN: 1448-2517, DOI: 10.1071/en18118
|Environmental Chemistry 16/1||2020-02-05|
Zongbao Liu, Uli KlÃ¼mper, Yang Liu, Yuchun Yang, Qiaoyan Wei, Jih-Gaw Lin, Ji-Dong Gu, Meng Li
Metagenomic and metatranscriptomic analyses reveal activity and hosts of antibiotic resistance genes in activated sludge
published pages: 208-220, ISSN: 0160-4120, DOI: 10.1016/j.envint.2019.05.036
|Environment International 129||2020-02-05|
Kornelia Smalla, Kimberly Cook, Steven P Djordjevic, Uli KlÃ¼mper, Michael Gillings
Environmental dimensions of antibiotic resistance: assessment of basic science gaps
published pages: , ISSN: 1574-6941, DOI: 10.1093/femsec/fiy195
|FEMS Microbiology Ecology 94/12||2020-02-05|
Zongbao Liu, Uli KlÃ¼mper, Lei Shi, Lei Ye, Meng Li
From Pig Breeding Environment to Subsequently Produced Pork: Comparative Analysis of Antibiotic Resistance Genes and Bacterial Community Composition
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2019.00043
|Frontiers in Microbiology 10||2020-02-05|
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The information about "SARCOM" are provided by the European Opendata Portal: CORDIS opendata.
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