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H2020 projects about "mutation"

The page lists 132 projects related to the topic "mutation".

# achronym  title  year 
1 PRO-CF-MED Clinical Proof of concept for a RNA-targeting Oligonucleotide for a Cystic fibrosis-F508del MEDication 2015
2 GermAge The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem 2015
3 MoTriColor Molecularly guided trials with specific treatment strategies in patients with advanced newly molecular defined subtypes of colorectal cancer (MoTriColor) 2015
4 RevMito Deciphering and reversing the consequences of mitochondrial DNA damage 2015
5 CRCStemCellDynamics Molecular Subtype Specific Stem Cell Dynamics in Developing and Established Colorectal Cancers 2015
6 CULTURALBASE Social Platform on Cultural Heritage and European Identities 2015
7 InVivo_DDR_ADPR Decoding the DNA damage signalling in C. elegans by proteomic analyses of ADP-ribosylation 2016
8 DecipherBILU Understanding functional mechanisms leading to the BILU syndrome 2015
9 CICCI Characterization of Intestinal Cancer Cell Invasion 2015
10 BRIDGES Bioinformatic approaches to identify and detect both disease- and drug-related genomic alterations in breast cancer patients 2015
11 IntestineUb The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells 2016
12 MDR Tuberculosis Evolution and success of the multi-drug resistant M. tuberculosis SIT41 (LAM7-TUR) lineage 2015
13 PopMet Investigating bacterial strain evolution through metagenomic genome assemblies 2015
14 ROBUSTNET Quantitative developmental genetic analysis of phenotypic buffering and cryptic variation 2015
15 TARLOOP R-loops as a major modulator of transcription-associated recombination and chromatin dynamics 2015
16 TRIGGDRUG Reactions That Translate mRNA into Drug-like Molecules 2016
17 DUB-DECODE Systematic Decoding of Deubiquitylase-Regulated Signaling Networks 2015
18 STEMCARDIORISK Stem Cells for Cardiac Arrhythmia Risk Assessment 2015
19 StemNicheOnWaveCrest New therapies for myeloproliferative diseases based on multi-stage and -system analyses of the haematopoietic stem-cell niche 2015
21 SLACC Supplying lung adenocarcinoma cell lines to the cancer research community. 2015
22 CYTOPRO Profiling of tumour cells in blood for personalized treatment of metastatic cancer 2015
23 PhotoMutant Rational Design of Photoreceptor Mutants with Desired Photochemical Properties 2016
24 CODOVIREVOL Evolution of viral codon usage preferences:manipulation of translation accuracy and evasion of immune response 2016
25 TAT-CF Novel therapeutic approaches for the treatment of cystic fibrosis based on small molecule transmembrane anion transporters 2016
26 NetMoDEzyme Network models for the computational design of proficient enzymes 2016
27 PreventStoCan Understanding microbe-induced stomach cancer – the key to a workable strategy for worldwide prevention 2016
28 hRBP-virion Comprehensive identification of host factors involved in the early steps of HIV infection. 2017
29 iGEMMdev Development and Characterisation of New Immunogenic GEMMs of Lung Cancer 2017
30 ENVERESP Crosstalk between nuclear envelope and DNA Damage Response: Role of nucleoporin TPR in the maintenance of genomic integrity 2016
31 CAMEOS Cardiac micro-engineered tissue for high-throughput screening 2016
32 CYgnaling Probing the role of orphan Cytochrome P450 oxygenases in signaling compounds biosynthesis in plants by a comparative genomics and gene conservation approach 2016
33 DesignerAntibiotics Towards the prevention of aminoglycoside antibiotic-related deafness 2017
35 EpigenomeProgramming An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell 2016
36 nextDART Next-generation Detection of Antigen Responsive T-cells 2016
37 DENOVOMUT An integrated approach to understanding the impact of de novo mutations on the mammalian genome 2017
38 DMD2CURE Correction of duplications in the DMD gene by a CRISPR/Cas9 approach 2017
39 TENSION Targeting replication stress recovery pathways in oncology 2016
40 MUTX MUTATION++ library, technology transfer from atmospheric entry plasmas to biomass pyrolysis 2016
41 TransSplicHD Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. 2016
42 SYNTRAIN Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network 2016
43 1toStopVax RNA virus attenuation by altering mutational robustness 2016
44 BRAIN REPEATS Repeat polymorphisms as genetic modifiers of brain function in healthy subjects and Huntington disease mutation carriers 2016
45 URBACH-ALZ Hyper-emotionality after neurodegenerative loss of inhibition of the amygdala 2017
46 LungCARD Blood test for clinical therapy guidance of non-small cell lung cancer patients 2017
47 GENE FOR CURE Expanding and extending gene therapy of monogenic diseases of the haematopoietic system 2016
48 IMMUNOSABR Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer 2017
49 TREATCilia Novel Therapeutic Avenues for dynein-related Ciliopathies 2017
50 CureTheCloves PIK3CA inhibition in patients with the CLOVES syndrome 2017
51 DSR Dissipative Self-Replication 2017
52 SARCOM Selection for antimicrobial resistance in a complex community context 2017
53 MultiLevelLandscape Multilevel Selection for Specificity and Divergence in Bacteria 2017
54 MuRChap The mutation-buffering capacity of RNA chaperones 2017
55 ResistEpist Dissection of the mechanisms causing the epistasis between antibiotic resistance mutations in Escherichia coli 2018
56 MuSCel Genome Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization 2017
57 NeuroTRACK Tracking and predicting neurodegeneration spreading across the brain connectome 2017
58 Rep. Fork Restart Restart of blocked replication fork at replication fork barrier 2017
59 OPTiAGE The trade-off between longevity and reproduction: optimal control of aging 2018
60 DSMT16 Deciphering causes and consequences of inflammation in subtypes of sporadic intestinal cancer 2018
61 BaskAtax Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders 2017
62 mtDNA-CURE Treating mitochondrial disease caused by pathogenic mtDNA mutations 2018
63 BRCA-ERC Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control 2017
64 V-EPC Inherited disfunctions of brain microcirculation 2017
65 GermlineAgeingSoma Getting to the root of ageing: somatic decay as a cost of germline maintenance 2017
66 CRISS CRISPR Gene Correction for Severe Combined Immunodeficiency Caused by Mutations in Recombination-activating gene 1 and 2 (RAG1 and RAG2) 2017
67 INSITUMUT Direct detection of cancer-causing mutations in tumour specimens 2018
68 EvoCellBio A combined in vitro and in vivo approach to dissect biochemical network evolution. 2018
69 CLLCLONE Harnessing clonal evolution in chronic lymphocytic leukemia 2018
70 ZIDOMS Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan Syndrome 2018
71 EScORIAL Emerging Simplex ORigins In ALS 2018
72 PSR Photometabolic Self-Replication 2019
73 PrunMut Candidate mutation discovery in early-flowering mutants 'Rojo Pasión Precoz' and 'Bulida Precoz' 2019
74 SunPro Sunflower: Durable Resistance to Broomrape (Orobanche cumana Wallr.) 2019
75 PREMEDiCARE PREcision MEDicine with induced pluripotent stem cells for Cardiac Arrhythmias Risk Evaluation 2018
76 INFLA-AID The role of NLRC4 inflammasome in autoinflammatory diseases 2018
77 EvolBehavGenArch The composition and evolution of C. elegans behavioural genetic architectures 2018
78 HiMIN Histone H3.3 oncogenic mutations: a role in genome instability through altered DNA repair and replication fork stability? 2018
79 MiniBRAIN Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. 2019
80 ProMeta Non-histone protein acetylation targets of KAT2A in AML 2018
81 GENOMIA Genomic Modifiers of Inherited Aortapathy 2019
82 SILICOFCM In Silico trials for drug tracing the effects of sarcomeric protein mutations leading to familial cardiomyopathy 2018
83 LEAP-EXTREME Local Edaphic Adaptation in Plants through Leveraging an Extremophile Model 2018
84 cGEM the Center for Genomics, Evolution and Medicine 2018
85 PITBUL Point-of-Care implementation of TB testing with ultra-fast Local Heating PCR 2017
86 Fields4CAT Force Fields in Redox Enzymatic Catalysis 2019
87 BioBalanced Feasibility study for Bioapplications – BioBalanced Farm probiotic 2018
88 BSLchlamy Understanding the essential function of the conserved plant-specific protein phosphatase family BSL 2018
89 SIGNIA SIGNIA: An innovative drug discovery platform for rapid identification and validation of antimicrobial applications in available pharmaceutical resources and drugs open for repurposing. 2018
90 EVOdrops directed EVOlution in DROPS 2018
91 Growth regulation The wide-spread bacterial toxin delivery systems and their role in multicellularity 2019
92 Myel-IN-Crisis Myelin at the crossroads of Development and Disease 2018
93 BioRoboost Fostering Synthetic Biology standardisation through international collaboration 2018
94 UNIFLUVAC A novel universal influenza vaccine targeting epitopes of limited variability 2018
95 StarT European Training Network to Diagnose, Understand and Treat Stargardt Disease, a Frequent Inherited Blinding Disorder 2018
96 SOLID Suppression of Organelle Defects in Human Disease 2019
97 HYPROTIN Hyperpolarized Nuclear Magnetic Resonance Spectroscopy for Time-Resolved Monitoring of Interactions of Intrinsically Disordered Breast-Cancer Proteins 2019
98 evolSingleCellGRN Constraint, Adaptation, and Heterogeneity: Genomic and single-cell approaches to understanding the evolution of developmental gene regulatory networks 2019
99 Agglomerates Infinite Protein Self-Assembly in Health and Disease 2019
100 CiliaTubulinCode Self-organization of the cilium: the role of the tubulin code 2019
101 ONCOFUM Integrating the tissue-specificity and chronology of hereditary renal cancer predisposition 2019
102 IMaP Imaging tumor vessels as a marker for p53 mutation status in cancer 2020
103 GPCR-MS Molecular Details of Membrane Protein Receptor Dynamics 2019
104 SOS-CROPS Solving the tangled ontogenesis of the stem for sustainable crops 2019
105 MutANTs Mutation rate evolution in attine ants 2020
106 iMIND iPS-derived MIcroglia and Neuroinflammation in Dementia 2020
107 2D-MES Two Dimensional Molecular Electronics Spectroscopy for DNA/RNA Mutation Recognition 2020
108 PMLingAML Using PML nuclear body biology to identify potential AML treatment targets 2020
109 GenDels Development of a new CRISPR-Cas3-based tool for large genomic deletions 2019
110 MalusEdit Malus genome editing via CRISPR/Cas9 to develop sustainable pest free apples 2019
111 MechanoMVP Mechanosensing and Mitral Valve Prolapse: from the Molecular Mechanisms to the Progression of the Disease 2019
112 IBL-302 Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer 2019
113 Genetic Vaccine Study the therapeutic and preventive potential of targeting oncogenic mutations with CRISPR-Cas9 technology 2019
114 SPELITEC Sequence sPecific ELImination of shiga-Toxin E. Coli 2019
115 RASMAC Regulatory Approved Software for Mutation Analysis in Cancer 2019
116 FUELING-TRANSPORT Deciphering the Role of Huntingtin in Energy Supply for Axonal Transport in Health and Huntington’s Disease 2020
117 MOLEC ANTI-ARRHYT Resilience and Trigger Factors in Cardiac Arrhythmia: Risk Stratification and Drug Design 2020
118 GEMS Genetically Evolving Models of Science 2019
119 RhabdoEvo Deciphering the cellular origin and evolution of malignant rhabdoid tumors 2019
120 BIND Brain Involvement iN Dystrophinopathies 2020
121 DPR-VAX Dipeptide-Repeat Vaccine to prevent ALS and FTD in C9orf72 mutation carriers 2020
122 PROMISE PROgrammable MIxed Signal Electronics 2020
123 RNAVirFitness The dark side of evolution: the deleterious mutational landscape of RNA viruses 2020
124 ROMB Retina Organoid Mechanobiology 2020
125 EvolInfome The sources of historical signal in the genomes of birds 2021
126 DIFFER Determinants of genetic diversity: Important Factors For Ecosystem Resilience 2020
127 ParkIFNAR Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. 2020
128 MITafterVIT Unravelling maintenance mechanisms of immune tolerance after termination of venom immunotherapy by means of clonal mast cell diseases 2020
129 NOSCAR decipheriNg Oncogenic SIgnalling patterns to break CAncer drug Resistance 2020
130 HiPhy High Phytosterol variants towards improved feedstocks and biofortification of crops 2020
131 SecondCANCERinKIDS What causes therapy-related malignancies in childhood cancer survivors? Dissecting the etiology of second cancers 2020
132 ObeSIK3 Role of SIK3 in energy homeostasis 2021