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STORM SIGNED

Signal Transduction in Organic Materials

Total Cost €

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EC-Contrib. €

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Partnership

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Project "STORM" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT DELFT 

Organization address
address: STEVINWEG 1
city: DELFT
postcode: 2628 CN
website: www.tudelft.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙998˙985 €
 EC max contribution 1˙998˙985 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-COG
 Funding Scheme ERC-COG
 Starting year 2017
 Duration (year-month-day) from 2017-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT DELFT NL (DELFT) coordinator 1˙998˙985.00

Map

 Project objective

It is the overall aim of this project to use responsive catalysts to introduce signal transduction cascades in soft materials, enabling autonomous, programmable and amplified response of soft materials to chemical signals from their environment. 'Smart' soft materials could find many important applications ranging from personalized therapeutics to soft robotics. However, as most molecular materials are unable to communicate, or even respond to, changes in their environment, truly smart materials are still far out of reach. Signal transduction is one of the primary processes used by living cells to react to events taking place in their environment, often involving a signal triggering enzymatic activity, leading to a cellular response. Such rudimentary communication is entirely non-existent in synthetic materials. I here propose the introduction of catalysis-based signal transduction between chemical systems to enable synthetic materials to respond autonomously to events taking place in their environment. Key to achieving this objective will be the development of switchable catalysts, using signals originating from chemical events to change catalytic activity, and coupling changes in catalytic activity to responses in soft materials. In achieving these objectives, I will develop new design strategies for responsive soft materials, enabling control over material formation and response in time and space, through autonomous reaction to chemical signals. This will allow the development of new actuators, self-healing materials, sensors, therapeutics and self-regulation and self-correction of material assembly. It will also constitute an entirely new role for catalysis, as catalysis will be engaged to constitute a first step towards achieving communication between artificial chemical systems.

 Publications

year authors and title journal last update
List of publications.
2020 Rienk Eelkema, Andrij Pich
Pros and Cons: Supramolecular or Macromolecular: What Is Best for Functional Hydrogels with Advanced Properties?
published pages: 1906012, ISSN: 0935-9648, DOI: 10.1002/adma.201906012
Advanced Materials 2020-02-06
2018 Chandan Maity, Fanny Trausel, Rienk Eelkema
Selective activation of organocatalysts by specific signals
published pages: 5999-6005, ISSN: 2041-6520, DOI: 10.1039/c8sc02019a
Chemical Science 9/27 2020-01-14
2018 Fanny Trausel, Bowen Fan, Susan A. P. van Rossum, Jan H. van Esch, Rienk Eelkema
Aniline Catalysed Hydrazone Formation Reactions Show a Large Variation in Reaction Rates and Catalytic Effects
published pages: 2571-2576, ISSN: 1615-4150, DOI: 10.1002/adsc.201800342
Advanced Synthesis & Catalysis 360/13 2020-01-14
2019 Bowen Fan, Yongjun Men, Susan A. P. Rossum, Guotai Li, Rienk Eelkema
A Fuel‐Driven Chemical Reaction Network Based on Conjugate Addition and Elimination Chemistry
published pages: , ISSN: 2570-4206, DOI: 10.1002/syst.201900028
ChemSystemsChem 2020-01-14

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The information about "STORM" are provided by the European Opendata Portal: CORDIS opendata.

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