Explore the words cloud of the UbiCODE project. It provides you a very rough idea of what is the project "UbiCODE" about.
The following table provides information about the project.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
|Coordinator Country||France [FR]|
|Total cost||3˙407˙194 €|
|EC max contribution||3˙407˙194 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2018-01-01 to 2021-12-31|
Take a look of project's partnership.
|1||CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS||FR (PARIS)||coordinator||525˙751.00|
|2||UNIVERSITY OF DUNDEE||UK (DUNDEE)||participant||546˙575.00|
|3||ACADEMISCH ZIEKENHUIS LEIDEN||NL (LEIDEN)||participant||510˙748.00|
|4||NOVO NORDISK A/S||DK (BAGSVAERD)||participant||290˙081.00|
|5||THE UNIVERSITY OF LIVERPOOL||UK (LIVERPOOL)||participant||273˙287.00|
|6||FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION||CH (BASEL)||participant||265˙226.00|
|7||INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH||DE (MAINZ)||participant||249˙216.00|
|8||JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN||DE (FRANKFURT AM MAIN)||participant||249˙216.00|
|9||MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV||DE (MUENCHEN)||participant||249˙216.00|
|10||ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS||ES (DERIO VIZCAYA)||participant||247˙872.00|
|11||MEDICAL RESEARCH COUNCIL||UK (SWINDON)||participant||0.00|
|12||Basque Country University||ES (Leioa)||partner||0.00|
|14||Merck KGaA||DE (DARMSTADT)||partner||0.00|
|15||Nova Medical School||PT (Lisboa)||partner||0.00|
|17||The Naked Scientists Ltd||UK (Cambridge)||partner||0.00|
|19||Ubiquigent Ltd||UK (Dundee)||partner||0.00|
|20||YELLOW RESEARCH||NL (AMSTERDAM)||partner||0.00|
Essential role of protein modification by members of the Ubiquitin family: Post-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate protein function at several levels: to change their localisation, activity, their interaction with partner proteins or their stability at the right time and cellular compartment, according to the cell requirements. Defects in this homeostatic equilibrium result in pathologies such as cancer, neurodegeneration, inflammation or multiple infections. For this reason, this research area has become very attractive for fundamental scientists as well as for the pharmaceutical industry aiming to identify potential targets for therapeutic intervention. Ub family members hold a homeostatic equilibrium within the cell and are interconnected in various ways including the regulation of enzymes that control the modified status of target proteins. Interestingly, Ub and Ub-like (UbL) proteins can modify themselves, forming intricate and complex chains. This landscape has recently expanded with the discovery of the formation of heterologous chains among UbL molecules including SUMO or NEDD8 but also other PTMs such as phosphorylation or acetylation. This unsuspected complexity of what is now known as the «Ubiquitin Code», which is an unknown universal language that needs to be deciphered to understand protein homeostasis and its associated pathologies. To decrypt this complex code requires joint collaborative multidisciplinary efforts at all levels, including the use of distinct molecular systems and model organisms and the latest technological developments to explore chemical, biochemical, molecular, pharmacological and clinical aspects of protein modification by members of the Ub family. UbiCODE represents an unprecedented effort to understand this code in an integrated manner.
|Supervisory Board||Other||2020-04-16 14:16:31|
|Outreach and research article publications, meetings, events||Documents, reports||2020-04-16 14:16:26|
|UbiCODE website launched and updated and presence in social media||Websites, patent fillings, videos etc.||2020-04-16 14:16:21|
Take a look to the deliverables list in detail: detailed list of UbiCODE deliverables.
|year||authors and title||journal||last update|
Zuzanna Kozicka, Georg Petzold, Nicolas H. ThomÃ¤
Taking the Brakes Off Targeted Protein Degradation
published pages: 16-18, ISSN: 2451-9456, DOI: 10.1016/j.chembiol.2019.12.010
|Cell Chemical Biology 27/1||2020-02-05|
David A. PÃ©rez Berrocal, Katharina F. Witting, Huib Ovaa, Monique P. C. Mulder
Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code
published pages: , ISSN: 2296-2646, DOI: 10.3389/fchem.2019.00931
|Frontiers in Chemistry 7||2020-02-04|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "UBICODE" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "UBICODE" are provided by the European Opendata Portal: CORDIS opendata.
Interdisciplinary connectivity: Understanding and managing complex systems using connectivity scienceRead More
Glyco-Nanoparticles for Applications in Advance NanomedicineRead More
Supporting the interaction of Humans and Automated vehicles: Preparing for the EnvIronment of TomorrowRead More