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MECADISTEM

A new and innovative method to extract adipose Stromal Vascular Fraction: Application in post-prostatectomy erectile dysfunction

Total Cost €

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EC-Contrib. €

0

Partnership

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 MECADISTEM project word cloud

Explore the words cloud of the MECADISTEM project. It provides you a very rough idea of what is the project "MECADISTEM" about.

stemcis    imposed    once    12    enzymes    patients    substantial    cure    post    tissues    urologists    grinding    hire    adult    secure    expecting    methodology    savings    therapies    proven    operations    life    treatment    erectile    single    filtration    surgical    damages    cells    extract    finalise    prostatectomy    avoiding    simply    cancer    point    complication    commercial    feasibility    roi    svf    treat    enzymatic    people    preparation    alternatives    validated    progenitor    centrifugation    preclinical    million    damaged    rp    surgeons    adipose    profits    unmet    clinical    regenerating    milestones    form    digestion    repair    vascular    market    mecadistem    men    stromal    dysfunction    fraction    frequent    medical    money    cellular    tools    radical    view    impairs    ed    quality    collagenase    financial    candidate    cell    kit    minutes    extracted    mechanically    stem    tissue    isolate    constraints    hold    shown    prostate    time    gain    28    efficient   

Project "MECADISTEM" data sheet

The following table provides information about the project.

Coordinator
STEMCIS SAS 

Organization address
address: 2 RUE MAXIME RIVIERE
city: SAINTE CLOTILDE
postcode: 97490
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.stemcis.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STEMCIS SAS FR (SAINTE CLOTILDE) coordinator 50˙000.00

Map

 Project objective

Erectile dysfunction (ED) is a significant and common medical problem which impairs quality of life of men and their partners. ED is a frequent complication after a radical prostatectomy (RP) due to surgical treatment for prostate cancer. For this condition, ED represents a significant unmet medical need, since there is no efficient treatment to repair the cellular damages following a RP. Clinical implementation of stem cell treatment represents a potential candidate for ED treatment after RP. Adult progenitor cells extracted from adipose tissue, called Stromal Vascular Fraction (SVF) have shown promising results in preclinical and clinical studies to treat post-RP ED. STEMCIS has developed a unique kit to isolate the adipose cells which hold the potential to cure post-prostatectomy ED by regenerating the damaged tissues. MECADISTEM comes in the form of a single-use kit that includes all the tools necessary to simply and rapidly (less than 30 minutes) extract adipose tissue progenitor cells mechanically (grinding, centrifugation, filtration). Compared to the state-of-the-art alternatives using “collagenase (enzymatic) digestion”, MECADISTEM does not require the use of enzymes, avoiding the problems and constraints imposed by the use of this enzymatic digestion and offering substantial time and money savings, on both technical and surgical operations. Having validated this methodology in preclinical study, this project is planned to finalise the development and market preparation of this kit. In this Phase 1 Feasibility Study, we aim to evaluate the main milestones of the project from a technical, commercial and financial point of view. Once in the market, MECADISTEM will be used by urologists and surgeons to cure ED in patients following a RP, where the current therapies have not been proven effective. It will secure the growth for STEMCIS, expecting to gain over €12 million in profits, hire 6 new people and reach a ROI of €6.28 from this project after 5 years.

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The information about "MECADISTEM" are provided by the European Opendata Portal: CORDIS opendata.

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