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MECADISTEM

A new and innovative method to extract adipose Stromal Vascular Fraction: Application in post-prostatectomy erectile dysfunction

Total Cost €

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EC-Contrib. €

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Partnership

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 MECADISTEM project word cloud

Explore the words cloud of the MECADISTEM project. It provides you a very rough idea of what is the project "MECADISTEM" about.

stemcis    secure    post    stromal    surgeons    cells    regenerating    prostate    savings    mechanically    time    validated    proven    financial    methodology    surgical    expecting    28    adult    money    impairs    million    digestion    complication    form    once    medical    profits    avoiding    urologists    extracted    enzymatic    tissue    hold    preclinical    frequent    milestones    clinical    svf    kit    point    substantial    preparation    mecadistem    gain    cure    quality    roi    tools    prostatectomy    dysfunction    progenitor    repair    erectile    cell    single    fraction    12    shown    alternatives    cancer    simply    treatment    isolate    rp    collagenase    treat    men    damages    patients    people    adipose    centrifugation    constraints    view    market    cellular    minutes    feasibility    imposed    vascular    unmet    ed    finalise    radical    damaged    candidate    grinding    enzymes    life    efficient    filtration    operations    commercial    extract    stem    hire    therapies    tissues   

Project "MECADISTEM" data sheet

The following table provides information about the project.

Coordinator
STEMCIS SAS 

Organization address
address: 2 RUE MAXIME RIVIERE
city: SAINTE CLOTILDE
postcode: 97490
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.stemcis.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STEMCIS SAS FR (SAINTE CLOTILDE) coordinator 50˙000.00

Map

 Project objective

Erectile dysfunction (ED) is a significant and common medical problem which impairs quality of life of men and their partners. ED is a frequent complication after a radical prostatectomy (RP) due to surgical treatment for prostate cancer. For this condition, ED represents a significant unmet medical need, since there is no efficient treatment to repair the cellular damages following a RP. Clinical implementation of stem cell treatment represents a potential candidate for ED treatment after RP. Adult progenitor cells extracted from adipose tissue, called Stromal Vascular Fraction (SVF) have shown promising results in preclinical and clinical studies to treat post-RP ED. STEMCIS has developed a unique kit to isolate the adipose cells which hold the potential to cure post-prostatectomy ED by regenerating the damaged tissues. MECADISTEM comes in the form of a single-use kit that includes all the tools necessary to simply and rapidly (less than 30 minutes) extract adipose tissue progenitor cells mechanically (grinding, centrifugation, filtration). Compared to the state-of-the-art alternatives using “collagenase (enzymatic) digestion”, MECADISTEM does not require the use of enzymes, avoiding the problems and constraints imposed by the use of this enzymatic digestion and offering substantial time and money savings, on both technical and surgical operations. Having validated this methodology in preclinical study, this project is planned to finalise the development and market preparation of this kit. In this Phase 1 Feasibility Study, we aim to evaluate the main milestones of the project from a technical, commercial and financial point of view. Once in the market, MECADISTEM will be used by urologists and surgeons to cure ED in patients following a RP, where the current therapies have not been proven effective. It will secure the growth for STEMCIS, expecting to gain over €12 million in profits, hire 6 new people and reach a ROI of €6.28 from this project after 5 years.

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The information about "MECADISTEM" are provided by the European Opendata Portal: CORDIS opendata.

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