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MECADISTEM

A new and innovative method to extract adipose Stromal Vascular Fraction: Application in post-prostatectomy erectile dysfunction

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

MECADISTEM project word cloud

Explore the words cloud of the MECADISTEM project. It provides you a very rough idea of what is the project "MECADISTEM" about.

post imposed regenerating hire finalise surgical secure gain expecting enzymatic isolate preparation frequent stem adult ed extract therapies medical treatment urologists operations repair commercial prostate time damages grinding once filtration damaged stromal preclinical kit quality extracted mecadistem market progenitor validated form tissues patients men view savings impairs treat radical efficient cure unmet stemcis shown surgeons proven hold roi 12 feasibility constraints collagenase single milestones tissue methodology 28 clinical minutes cellular erectile avoiding substantial simply cell million vascular rp people enzymes digestion mechanically point prostatectomy adipose profits complication tools svf fraction financial cells life money centrifugation cancer dysfunction candidate alternatives

Project "MECADISTEM" data sheet

The following table provides information about the project.

Coordinator	STEMCIS SAS Organization address address: 2 RUE MAXIME RIVIERE city: SAINTE CLOTILDE postcode: 97490 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.stemcis.com
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2019
Duration (year-month-day)	from 2019-05-01 to 2019-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	STEMCIS SAS STEMCIS SAS Organization address address: 2 RUE MAXIME RIVIERE city: SAINTE CLOTILDE postcode: 97490 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (SAINTE CLOTILDE)	coordinator	50˙000.00

Map

Project objective

Erectile dysfunction (ED) is a significant and common medical problem which impairs quality of life of men and their partners. ED is a frequent complication after a radical prostatectomy (RP) due to surgical treatment for prostate cancer. For this condition, ED represents a significant unmet medical need, since there is no efficient treatment to repair the cellular damages following a RP. Clinical implementation of stem cell treatment represents a potential candidate for ED treatment after RP. Adult progenitor cells extracted from adipose tissue, called Stromal Vascular Fraction (SVF) have shown promising results in preclinical and clinical studies to treat post-RP ED. STEMCIS has developed a unique kit to isolate the adipose cells which hold the potential to cure post-prostatectomy ED by regenerating the damaged tissues. MECADISTEM comes in the form of a single-use kit that includes all the tools necessary to simply and rapidly (less than 30 minutes) extract adipose tissue progenitor cells mechanically (grinding, centrifugation, filtration). Compared to the state-of-the-art alternatives using “collagenase (enzymatic) digestion”, MECADISTEM does not require the use of enzymes, avoiding the problems and constraints imposed by the use of this enzymatic digestion and offering substantial time and money savings, on both technical and surgical operations. Having validated this methodology in preclinical study, this project is planned to finalise the development and market preparation of this kit. In this Phase 1 Feasibility Study, we aim to evaluate the main milestones of the project from a technical, commercial and financial point of view. Once in the market, MECADISTEM will be used by urologists and surgeons to cure ED in patients following a RP, where the current therapies have not been proven effective. It will secure the growth for STEMCIS, expecting to gain over €12 million in profits, hire 6 new people and reach a ROI of €6.28 from this project after 5 years.

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