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PROBIOTEARS SIGNED

Probiotic-based Ophtalmologic treatment for Bacterial and Allergic Conjunctivitis

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 PROBIOTEARS project word cloud

Explore the words cloud of the PROBIOTEARS project. It provides you a very rough idea of what is the project "PROBIOTEARS" about.

toxicity    recurrent    vitro    trials    strains    expertise    avoidance    faster    resistances    probiotears    suitable    industrial    ocular    dimension    galenic    solid    broad    treatments    fast    biotics    strain    market    safety    scaling    inflammatory    global    eye    functional    reinforce    formula    million    worldwide    tests    stable    resistance    allergic    ipr    covered    vivo    issue    probiotics    health    pharmaceutical    pathogens    models    conjunctivitis    microbiota    regulatory    undesired    probiotic    antagonism    formulation    deeper    rising    company    supportive    ophthalmologists    animal    ab    generate    ophthalmic    innovation    intraocular    perform    drugs    protection    aligned    organisms    solution    pathogenic    industry    ready    1100    anti    ingredients    antihistaminic    reestablishment    competitor    bacterial    histaminic    ebitda    carry    clinical    infections    micro    14m    innovative    associations    risks    antibiotic    people    drops    ointments    healthy    mainly    validated    presented    strategy    feasibility    live    pressure   

Project "PROBIOTEARS" data sheet

The following table provides information about the project.

Coordinator		 AB BIOTICS SA 

Organization address
address: CALLE PARC DE RECERCA UAB CAMPUS AUB EDIFICIO DESPACHO P2M1 BELLATERRA
city: CERDANYOLA DEL VALLES
postcode: 8193
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Spain [ES]
 Project website http://www.ab-biotics.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.2.4. (Sustainable and competitive bio-based industries and supporting the development of a European bioeconomy)
2. H2020-EU.3.2.1. (Sustainable agriculture and forestry)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.3.2.2. (Sustainable and competitive agri-food sector for a safe and healthy diet)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-10-01   to  2018-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AB BIOTICS SA ES (CERDANYOLA DEL VALLES) coordinator 50˙000.00

Map

 Project objective

Conjunctivitis is a major health issue affecting more than 1100 million people worldwide. Currently, the market for bacterial & allergic conjunctivitis is mainly covered by antibiotic eye drops and ointments, which have undesired effects in the eye microbiota and contribute to increase the resistances of pathogenic strains. Other treatments such as anti-inflammatory and antihistaminic drugs have also undesired side effects and are not useful as an immediate solution.

AB-BIOTICS, a company with a broad expertise in developing functional ingredients for the pharmaceutical industry, has developed an innovative solution based on the use of probiotics. Probiotics are live micro-organisms allowing a fast and stable reestablishment of a healthy eye microbiota by providing: (1) faster anti-inflammatory and anti-histaminic effects; (2) antagonism to pathogens with no resistance risks; (3) protection against future/recurrent infections; and (4) avoidance of common side effects such as intraocular pressure rising.

The effects of the selected probiotic strains have been validated through functional in vitro and in vivo tests and its safety for ocular application has also been assessed in toxicity trials in animal models. The industrial scaling up of the strain has already been achieved and is now ready for galenic formulation.

In order to determine the key steps to bring PROBIOTEARS to the market within the next 2 years, the objectives of the presented feasibility study are: • Assess clinical ophthalmologists & users associations interest • Determine the most suitable formula for ophthalmic use • Define IPR strategy • Perform a deeper market & competitor analysis • Find key partners to carry out Supportive Clinical Trials in phase 2 • Assess Regulatory Requirements

PROBIOTEARS is a solid high-potential innovation project aligned with AB-BIOTICS’ strategy which is expected to reinforce its European & global dimension, and generate an EBITDA of 2,14M€.

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The information about "PROBIOTEARS" are provided by the European Opendata Portal: CORDIS opendata.

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