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PROBIOTEARS SIGNED

Probiotic-based Ophtalmologic treatment for Bacterial and Allergic Conjunctivitis

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 PROBIOTEARS project word cloud

Explore the words cloud of the PROBIOTEARS project. It provides you a very rough idea of what is the project "PROBIOTEARS" about.

presented    ocular    faster    formulation    allergic    health    global    market    deeper    safety    healthy    feasibility    expertise    rising    14m    anti    infections    eye    probiotics    million    carry    solid    pathogenic    histaminic    pharmaceutical    validated    probiotears    intraocular    inflammatory    drops    people    treatments    bacterial    ophthalmologists    ingredients    scaling    industry    ipr    1100    supportive    vivo    tests    broad    risks    probiotic    strategy    fast    ebitda    reestablishment    pathogens    aligned    live    ab    competitor    worldwide    ready    solution    formula    vitro    drugs    resistance    functional    suitable    antagonism    models    organisms    trials    innovation    toxicity    undesired    protection    reinforce    regulatory    industrial    issue    dimension    ointments    galenic    biotics    microbiota    recurrent    associations    strain    pressure    clinical    perform    generate    animal    stable    avoidance    mainly    ophthalmic    strains    conjunctivitis    resistances    company    covered    micro    antibiotic    antihistaminic    innovative   

Project "PROBIOTEARS" data sheet

The following table provides information about the project.

Coordinator		 AB BIOTICS SA 

Organization address
address: CALLE PARC DE RECERCA UAB CAMPUS AUB EDIFICIO DESPACHO P2M1 BELLATERRA
city: CERDANYOLA DEL VALLES
postcode: 8193
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Spain [ES]
 Project website http://www.ab-biotics.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.2.4. (Sustainable and competitive bio-based industries and supporting the development of a European bioeconomy)
2. H2020-EU.3.2.1. (Sustainable agriculture and forestry)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.3.2.2. (Sustainable and competitive agri-food sector for a safe and healthy diet)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-10-01   to  2018-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AB BIOTICS SA ES (CERDANYOLA DEL VALLES) coordinator 50˙000.00

Map

 Project objective

Conjunctivitis is a major health issue affecting more than 1100 million people worldwide. Currently, the market for bacterial & allergic conjunctivitis is mainly covered by antibiotic eye drops and ointments, which have undesired effects in the eye microbiota and contribute to increase the resistances of pathogenic strains. Other treatments such as anti-inflammatory and antihistaminic drugs have also undesired side effects and are not useful as an immediate solution.

AB-BIOTICS, a company with a broad expertise in developing functional ingredients for the pharmaceutical industry, has developed an innovative solution based on the use of probiotics. Probiotics are live micro-organisms allowing a fast and stable reestablishment of a healthy eye microbiota by providing: (1) faster anti-inflammatory and anti-histaminic effects; (2) antagonism to pathogens with no resistance risks; (3) protection against future/recurrent infections; and (4) avoidance of common side effects such as intraocular pressure rising.

The effects of the selected probiotic strains have been validated through functional in vitro and in vivo tests and its safety for ocular application has also been assessed in toxicity trials in animal models. The industrial scaling up of the strain has already been achieved and is now ready for galenic formulation.

In order to determine the key steps to bring PROBIOTEARS to the market within the next 2 years, the objectives of the presented feasibility study are: • Assess clinical ophthalmologists & users associations interest • Determine the most suitable formula for ophthalmic use • Define IPR strategy • Perform a deeper market & competitor analysis • Find key partners to carry out Supportive Clinical Trials in phase 2 • Assess Regulatory Requirements

PROBIOTEARS is a solid high-potential innovation project aligned with AB-BIOTICS’ strategy which is expected to reinforce its European & global dimension, and generate an EBITDA of 2,14M€.

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The information about "PROBIOTEARS" are provided by the European Opendata Portal: CORDIS opendata.

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