Explore the words cloud of the DYNASSEMBLY project. It provides you a very rough idea of what is the project "DYNASSEMBLY" about.
The following table provides information about the project.
Coordinator |
UNIVERSITY OF BRISTOL
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://www.claydenchemistry.net |
Total cost | 183˙454 € |
EC max contribution | 183˙454 € (100%) |
Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
Code Call | H2020-MSCA-IF-2016 |
Funding Scheme | MSCA-IF-EF-ST |
Starting year | 2018 |
Duration (year-month-day) | from 2018-01-01 to 2019-12-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | UNIVERSITY OF BRISTOL | UK (BRISTOL) | coordinator | 183˙454.00 |
By combining biology's information storage and replication strategies, namely specific hydrogen-bonding between nucleobases, with the potential for hydrogen-bond reorganisation in novel 'refoldable foldamers', we propose to develop a new, artificial but bio-inspired mechanism for the transfer of information in chemical systems. Based on preliminary modelling studies, we will focus on one type of polyurea structures, built from 'Nowick'-style motifs, which spontaneously fold in solution, forming intramolecular polarized hydrogen-bond networks. Upon addition of simple chemical additives forming competitive intermolecular hydrogen bonds with the foldamer, the directionality of these networks could be modified, transforming a conformational mixture to a well-defined unidirectional network. Molecular events such as reversible switching, chemical sensing, and long-distance information communication will be studied. Then, biomimetic additives such as nucleobases will be investigated, and their impact on the folding of the oligomers will be analysed. We will also investigate 3D hydrogen bond networks, which will provide highly functionalised, well-defined macromolecules in a bottom-up approach, and study the change of macromolecular structure and chirality upon stimulus. Finally, structures that give a non-spectroscopic 'readout' of the interaction with the additive will be built, which for example exhibit 'off-on' fluorescence or 'off-on' catalytic activity. The application of these foldamers in the construction of photochemically switchable molecular devices will also be investigated.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DYNASSEMBLY" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "DYNASSEMBLY" are provided by the European Opendata Portal: CORDIS opendata.
Multiparametric imaging of glioblastoma tumour heterogeneity for supporting treatment decisions and accurate prognostic estimation
Read More