Explore the words cloud of the CHANNELMAT project. It provides you a very rough idea of what is the project "CHANNELMAT" about.
The following table provides information about the project.
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
|Coordinator Country||Germany [DE]|
|Total cost||150˙000 €|
|EC max contribution||150˙000 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2017-10-01 to 2019-03-31|
Take a look of project's partnership.
|1||CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL||DE (KIEL)||coordinator||150˙000.00|
Cells respond to external mechanical stimuli through an activation of a cellular mechanism called mechanotransduction. The cellular responses in this mechanism are expressed by a modification in cellular proliferation, migration and differentiation, as well as in a strengthening of their adhesion. Likewise, diseases such as cancer and cardiac dysfunctions are also related to cellular mechanotransduction. Here we propose to take a novel 3D material porous material towards commercial applications. The material serves as a platform for controlling mechanotransduction (e.g. in implant materials) and enables a control of mechanotransduction by mimicking natural 3D cellular environments. Our material contains a novel form of microporous structures represented by micron-sized channels embedded in a polymer matrix of a well-defined stiffness that has been developed within the ERC project CELLINSPIRED. The material guarantees pore interconnectivity independently of pore density and size, a unique feature offered by our fabrication procedure, for which we have applied for a patent (EP 15166793.8, PCT/EP2016/060160). Furthermore, it also provides a large, three-dimensionally controlled cell-surface contact area, such that the mechanical properties of the environment will have large impact on the cells. Our goal in this project is to validate our novel material for cellular applications where mechanotransduction is targeted. The expected outcome of our project is to receive a demonstrator material that (1) has well-defined mechanical properties, porosities and pore dimensions, (2) is biocompatible and can be sterilized, (3) can be fabricated in different levels of complexity, (4) can activate mechanotransduction in cells, and (5) can be fabricated using high-throughput processes. As for commercialization, we aim to license the patent to biomaterials companies involved in applications that range from 3D cell cultures to implant materials.
|year||authors and title||journal||last update|
Mohammadreza Taale, Fabian SchÃ¼tt, Tian Carey, Janik Marx, Yogendra Kumar Mishra, Norbert Stock, Bodo Fiedler, Felice Torrisi, Rainer Adelung, Christine Selhuber-Unkel
Biomimetic Carbon Fiber Systems Engineering: A Modular Design Strategy To Generate Biofunctional Composites from Graphene and Carbon Nanofibers
published pages: 5325-5335, ISSN: 1944-8244, DOI: 10.1021/acsami.8b17627
|ACS Applied Materials & Interfaces 11/5||2019-06-06|
SÃ¶ren B. Gutekunst, Katharina Siemsen, Steven Huth, Anneke MÃ¶hring, Britta Hesseler, Michael Timmermann, Ingo Paulowicz, Yogendra Kumar Mishra, Leonard Siebert, Rainer Adelung, Christine Selhuber-Unkel
3D Hydrogels Containing Interconnected Microchannels of Subcellular Size for Capturing Human Pathogenic Acanthamoeba Castellanii
published pages: 1784-1792, ISSN: 2373-9878, DOI: 10.1021/acsbiomaterials.8b01009
|ACS Biomaterials Science & Engineering 5/4||2019-06-06|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "CHANNELMAT" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (firstname.lastname@example.org) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "CHANNELMAT" are provided by the European Opendata Portal: CORDIS opendata.
The Enemy of the Good: Towards a Theory of Moral ProgressRead More
Towards Realistic Modelling of Nucleosome Organization Inside Functional Chromatin DomainsRead More
Discovery and Characterization of Hydrogen-Based High-Temperature SuperconductorsRead More