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OACTIVE SIGNED

Advanced personalised, multi-scale computer models preventing OsteoArthritis

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

OACTIVE project word cloud

Explore the words cloud of the OACTIVE project. It provides you a very rough idea of what is the project "OACTIVE" about.

enjoyable combined healthcare inactive motivation onset diagnosis ranges form 65 whilst integration conclusively organ phenomenological empowered life levels simulate augmented oa environmental body risk degenerative intents pathophysiology combination causes cell interventions adherence progression models treatments individuals independence osteoarthritis susceptible patient data biomarkers usual articular computational framework explored optimal 30 patients mission quality holistic once predict population diagnostics mostly treatment ing tissue disease engagement big cartilage training overcoming mechanistic reduces 12 athletes oactive arthritis personalised sources slowing implicated outcomes interaction transforming prediction biochemical delaying manner elderly limitation social modeling dynamics simulations constructed joint adopting accelerating inflammatory generate predictors modifiable pain younger analytics mobility leap

Project "OACTIVE" data sheet

The following table provides information about the project.

Coordinator	EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED Organization address address: MAKEDONITISAS AVENUE 46 city: NICOSIA postcode: 1700 website: www.unic.ac.cy contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Cyprus [CY]
Project website	https://www.oactive.eu/
Total cost	4˙984˙033 €
EC max contribution	4˙984˙033 € (100%)
Programme	1. H2020-EU.3.1.5. (Methods and data)
Code Call	H2020-SC1-2017-CNECT-2
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-11-01 to 2020-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED Organization address address: MAKEDONITISAS AVENUE 46 city: NICOSIA postcode: 1700 website: www.unic.ac.cy contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (NICOSIA)	coordinator	521˙000.00
2	ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS Organization address address: CHARILAOU THERMI ROAD 6 KM city: THERMI THESSALONIKI postcode: 57001 website: www.certh.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (THERMI THESSALONIKI)	participant	506˙875.00
3	CENTER FOR TECHNOLOGY RESEARCH ANDINNOVATION (CETRI) LTD CENTER FOR TECHNOLOGY RESEARCH ANDINNOVATION (CETRI) LTD Organization address address: 77, John Kennedy Avenue city: Nicosia postcode: 1077 website: www.cetri.net contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (Nicosia)	participant	477˙000.00
4	SMARTEX S.R.L. SMARTEX S.R.L. Organization address address: VIA LUNGO IL FICARELLO 3 city: PRATO postcode: 59100 website: www.smartex.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PRATO)	participant	456˙062.00
5	LIVERPOOL JOHN MOORES UNIVERSITY LIVERPOOL JOHN MOORES UNIVERSITY Organization address address: RODNEY STREET 2 EGERTON COURT city: LIVERPOOL postcode: L3 5UX website: www.ljmu.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LIVERPOOL)	participant	444˙721.00
6	PANEPISTIMIO PATRON PANEPISTIMIO PATRON Organization address address: UNIVERSITY CAMPUS RIO PATRAS city: RIO PATRAS postcode: 265 04 website: www.upatras.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (RIO PATRAS)	participant	431˙250.00
7	ACONDICIONAMIENTO TARRASENSE ASSOCIACION ACONDICIONAMIENTO TARRASENSE ASSOCIACION Organization address address: CARRER DE LA INNOVACIO 2 city: TERRASSA postcode: 8225 website: www.leitat.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (TERRASSA)	participant	422˙500.00
8	FONDAZIONE RI.MED FONDAZIONE RI.MED Organization address address: VIA BANDIERA 11 city: PALERMO postcode: 90133 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PALERMO)	participant	399˙062.00
9	KATHOLIEKE UNIVERSITEIT LEUVEN KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	354˙062.00
10	FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA Organization address address: AV FERNANDO ABRIL MARTORELL 106 city: VALENCIA postcode: 46026 website: http://www.iislafe.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	317˙250.00
11	AXIA INNOVATION UG AXIA INNOVATION UG Organization address address: ZENETTISTRASSE 49 city: MUNCHEN postcode: 80337 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	248˙750.00
12	ANIMUS KENTRO APOTHERAPEIAS KAI APOKATASTASIS ANONYMI ETAIRIA ANIMUS KENTRO APOTHERAPEIAS KAI APOKATASTASIS ANONYMI ETAIRIA Organization address address: 8 KM LARISSA - TRIKALA city: LARISSA postcode: 41500 website: www.animus.com.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (LARISSA)	participant	218˙750.00
13	TIME.LEX TIME.LEX Organization address address: JOSEPH STEVENSSTRAAT 7 city: BRUSSEL postcode: 1000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUSSEL)	participant	186˙750.00

Map

Project objective

Osteoarthritis (OA) is a degenerative disease of the articular cartilage and the most common form of arthritis that causes joint pain, mobility limitation and, thus, reduces independence and overall quality of life. Although the usual population associated with the condition is the elderly (65 years old ranges from 12- 30%), who are mostly inactive, athletes and younger individuals are also susceptible. Whilst the available data have implicated the role of the various modifiable or non-modifiable risk factors in the development and progression of OA, no study has conclusively explored the interaction and integration of other information sets in a patient-specific manner. The current OACTIVE project intents to make a significant leap forward adopting a multi-scale holistic approach where patient-specific information from various levels, including cell, tissue, organ and whole body will be integrated and combined with information from other sources such as biochemical/inflammatory biomarkers, behaviour modeling and social/environmental risk factors to generate robust predictors for new personalised interventions for delaying onset and slowing down progression of OA. OACTIVE targets to patient-specific OA prediction and interventions by using a combination of mechanistic, phenomenological computational models, simulations and big data analytics. Once constructed, these models will be used to simulate and predict optimal treatments, better diagnostics, and improved patient outcomes. Overcoming the limitation of the current treatment interventions, Augmented Reality empowered interventions will be developed in a personalised framework allowing patients experience the treatment as more enjoyable, resulting in greater motivation, engagement, and training adherence. OACTIVE’s mission is to improve healthcare by transforming and accelerating the OA diagnosis and prediction based on a more comprehensive understanding of disease pathophysiology, dynamics, and patient outcomes.

Deliverables

List of deliverables.
Analysis of hardware devices and software tools. Game hardware and software design.	Documents, reports	2020-03-24 00:32:45
Data management plan Strategy	Documents, reports	2020-03-24 00:32:44
Data Collection protocol	Documents, reports	2020-03-24 00:32:44
OACTIVE Web Site and media presence	Demonstrators, pilots, prototypes	2020-03-24 00:32:44
First version of Ethics and Safety Manual	Documents, reports	2020-03-24 00:32:44
User Behaviour Modelling Documentation	Documents, reports	2020-03-24 00:32:45
User requirements analysis report	Documents, reports	2020-03-24 00:32:44

Take a look to the deliverables list in detail: detailed list of OACTIVE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Dimitar Stanev, Konstantinos Moustakas Stiffness modulation of redundant musculoskeletal systems published pages: 101-107, ISSN: 0021-9290, DOI: 10.1016/j.jbiomech.2019.01.017	Journal of Biomechanics 85	2020-03-24
2019	Dimitar Stanev, Konstantinos Moustakas Modeling musculoskeletal kinematic and dynamic redundancy using null space projection published pages: e0209171, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0209171	PLOS ONE 14/1	2020-03-24
2018	D.Stanev, K. Moustakas The Effect of Kinematic and Dynamic Redundancy on the Assessment of Joint Reaction Loads published pages: , ISSN: , DOI:		2020-03-24

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The information about "OACTIVE" are provided by the European Opendata Portal: CORDIS opendata.

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