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OACTIVE SIGNED

Advanced personalised, multi-scale computer models preventing OsteoArthritis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 OACTIVE project word cloud

Explore the words cloud of the OACTIVE project. It provides you a very rough idea of what is the project "OACTIVE" about.

data    personalised    progression    modifiable    models    treatment    disease    risk    interventions    prediction    oactive    oa    limitation    patient    outcomes   

Project "OACTIVE" data sheet

The following table provides information about the project.

Coordinator
EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED 

Organization address
address: MAKEDONITISAS AVENUE 46
city: NICOSIA
postcode: 1700
website: www.unic.ac.cy

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Cyprus [CY]
 Total cost 4˙984˙033 €
 EC max contribution 4˙984˙033 € (100%)
 Programme 1. H2020-EU.3.1.5. (Methods and data)
 Code Call H2020-SC1-2017-CNECT-2
 Funding Scheme /RIA
 Starting year 2017
 Duration (year-month-day) from 2017-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED CY (NICOSIA) coordinator 521˙000.00
2    ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS EL (THERMI THESSALONIKI) participant 506˙875.00
3    CENTER FOR TECHNOLOGY RESEARCH AND INNOVATION (CETRI) LTD CY (LIMASSOL) participant 477˙000.00
4    SMARTEX S.R.L. IT (PRATO) participant 456˙062.00
5    LIVERPOOL JOHN MOORES UNIVERSITY UK (LIVERPOOL) participant 444˙721.00
6    PANEPISTIMIO PATRON EL (RIO PATRAS) participant 431˙250.00
7    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) participant 422˙500.00
8    FONDAZIONE RI.MED IT (PALERMO) participant 399˙062.00
9    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 354˙062.00
10    FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA ES (VALENCIA) participant 317˙250.00
11    AXIA INNOVATION UG DE (MUNCHEN) participant 248˙750.00
12    ANIMUS KENTRO APOTHERAPEIAS KAI APOKATASTASIS ANONYMI ETAIRIA EL (LARISSA) participant 218˙750.00
13    TIME.LEX BE (BRUSSEL) participant 186˙750.00

Mappa

 Project objective

Osteoarthritis (OA) is a degenerative disease of the articular cartilage and the most common form of arthritis that causes joint pain, mobility limitation and, thus, reduces independence and overall quality of life. Although the usual population associated with the condition is the elderly (65 years old ranges from 12- 30%), who are mostly inactive, athletes and younger individuals are also susceptible. Whilst the available data have implicated the role of the various modifiable or non-modifiable risk factors in the development and progression of OA, no study has conclusively explored the interaction and integration of other information sets in a patient-specific manner. The current OACTIVE project intents to make a significant leap forward adopting a multi-scale holistic approach where patient-specific information from various levels, including cell, tissue, organ and whole body will be integrated and combined with information from other sources such as biochemical/inflammatory biomarkers, behaviour modeling and social/environmental risk factors to generate robust predictors for new personalised interventions for delaying onset and slowing down progression of OA. OACTIVE targets to patient-specific OA prediction and interventions by using a combination of mechanistic, phenomenological computational models, simulations and big data analytics. Once constructed, these models will be used to simulate and predict optimal treatments, better diagnostics, and improved patient outcomes. Overcoming the limitation of the current treatment interventions, Augmented Reality empowered interventions will be developed in a personalised framework allowing patients experience the treatment as more enjoyable, resulting in greater motivation, engagement, and training adherence. OACTIVE’s mission is to improve healthcare by transforming and accelerating the OA diagnosis and prediction based on a more comprehensive understanding of disease pathophysiology, dynamics, and patient outcomes.

 Work performed, outcomes and results:  advancements report(s) 

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The information about "OACTIVE" are provided by the European Opendata Portal: CORDIS opendata.

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