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Instand-NGS4P SIGNED

Integrated and standardized NGS workflows for Personalised therapy

Total Cost €

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EC-Contrib. €

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Partnership

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Project "Instand-NGS4P" data sheet

The following table provides information about the project.

Coordinator
MEDIZINISCHE UNIVERSITAT GRAZ 

Organization address
address: AUENBRUGGERPLATZ 2
city: GRAZ
postcode: 8036
website: http://www.medunigraz.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 12˙220˙142 €
 EC max contribution 10˙998˙128 € (90%)
 Programme 1. H2020-EU.3.1.5. (Methods and data)
 Code Call H2020-SC1-2019-Single-Stage-RTD
 Funding Scheme PCP
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MEDIZINISCHE UNIVERSITAT GRAZ AT (GRAZ) coordinator 8˙140˙561.00
2    ST. ANNA KINDERKREBSFORSCHUNG AT (WIEN) participant 316˙953.00
3    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) participant 315˙514.00
4    UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA IT (MILANO) participant 277˙456.00
5    UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN DE (Lübeck) participant 266˙657.00
6    UNIVERSITA DEGLI STUDI DI FIRENZE IT (Florence) participant 263˙957.00
7    CENTRE DE LUTTE CONTRE LE CANCER LEON BERARD FR (LYON) participant 261˙257.00
8    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 152˙685.00
9    INTERNATIONAL PREVENTION RESEARCH INSTITUT-IPRI MANAGEMENT FR (LYON) participant 127˙530.00
10    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 124˙503.00
11    EUROPEAN CANCER PATIENT COALITION BE (BRUXELLES) participant 122˙478.00
12    UNIVERZA V LJUBLJANI SI (LJUBLJANA) participant 121˙635.00
13    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) participant 120˙960.00
14    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) participant 100˙980.00
15    FEDERAZIONE ITALIANA DELLE ASSOCIAZIONI DI VOLONTARIATO IN ONCOLOGIA IT (ROMA) participant 93˙690.00
16    ORGANISATION OF EUROPEAN CANCER INSTITUTES BE (BRUXELLES) participant 82˙093.00
17    DIN DEUTSCHES INSTITUT FUER NORMUNG E.V. DE (BERLIN) participant 70˙200.00
18    BIOXPEDIA AS DK (AARHUS) participant 39˙015.00

Map

 Project objective

Instand-NGS4P is a 60-month PCP project federating 7 leading medical centers (two are coordinating ERNs) as buyers’ group with major experience in using different NGS platforms in research and routine diagnostics. The consortium is further strengthened by European patient advocacy groups, a standardization organization and partners participating in the European infrastructures BBMRI-ERIC, ELIXIR as well as several NGS-related EU programs to cover all technical aspects and transversal needs & requirements. Driven by patient and clinical needs, innovative NGS workflows from sample-pre-analytics to medical decision making will be developed. The modular design of the workflow will particularly enable SEMs to contribute, and provides flexibility to adopt emerging user needs and technologies. Specifications will address regulatory requirements for IVDs and refer to international standards and requests development of reference materials and implementation of EQA schemes covering the whole workflow. R&D suppliers will be selected based on a public tender all along this PCP process in 3 phases according to the best-value for money solution. The 3 phases foresee the leverage of 4 technical modules (pre-analytics, sequencing, bioinformatics, e-reporting/e-medication) and their standardized interfaces – from design (Phase 1) to prototypes (Phase 2), and full integration in Phase 3. At the end, this PCP will provide 2 fully integrated, standardized NGS workflows for routine diagnostics of common and rare cancers from adults to children. In order to enable broad implementation in healthcare systems throughout Europe and beyond and to increase benefit to patients a series of support activities are planned including communication and dissemination activities targeting a broad stakeholder community, development of training and education material for healthcare professionals and patients, health economic assessment and engagement with healthcare payers and policy makers.

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The information about "INSTAND-NGS4P" are provided by the European Opendata Portal: CORDIS opendata.

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