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CanBioSe SIGNED

Novel 1D photonic metal oxide nanostructures for early stage cancer detection

Total Cost €

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EC-Contrib. €

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Partnership

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 CanBioSe project word cloud

Explore the words cloud of the CanBioSe project. It provides you a very rough idea of what is the project "CanBioSe" about.

deposition    human    dimensional    papers    cells    au    ideas    immobilization    bioselective    personal    portable    training    biosensor    photonic    electrospinning    lymphocyte    commercialization    electrophoresis    foreseen    layer    co    tool    innovation    health    photoluminescence    auditories    cvs    ald    respectively    metal    biosensors    vice    polimer    market    strengthen    chronic    microfluidics    canbiose    transfer    optical    nanotechnology    cll    society    nanostructured    supervising    preparation    spectroscopy    stage    collaborative    nanostructures    oxides    deposited    conference    international    leukemia    antibodies    sharing    students    zno    formed    lymphoblastic    signal    scientific    minimize    dimensions    functionalization    leucosis    atomic    1d    nanomaterials    intersectoral    al2o3    bioengineering    performed    goals    microfluidic    simplify    nanolaminates    recording    versa    nanofibers    interdisciplinary    theses    cancer    detection    proposals    nanoparticles    oxide    technique    surface    acute    coat    skills    lasting   

Project "CanBioSe" data sheet

The following table provides information about the project.

Coordinator
LATVIJAS UNIVERSITATE 

Organization address
address: RAINIS BOULEVARD 19
city: RIGA
postcode: 1586
website: http://www.lu.lv

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Latvia [LV]
 Total cost 1˙282˙500 €
 EC max contribution 1˙282˙500 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2017
 Funding Scheme MSCA-RISE
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LATVIJAS UNIVERSITATE LV (RIGA) coordinator 423˙000.00
2    UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU PL (POZNAN) participant 333˙000.00
3    VILNIAUS UNIVERSITETAS LT (VILNIUS) participant 207˙000.00
4    ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER FR (MONTPELLIER CEDEX 5) participant 112˙500.00
5    MATERIALS RESEARCH CENTER UA (KIEV) participant 58˙500.00
6    NANO PRIME SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA PL (DEBICA) participant 54˙000.00
7    BIOSENSOR SRL IT (FORMELLO) participant 49˙500.00
8    FONDAZIONE BRUNO KESSLER IT (TRENTO) participant 36˙000.00
9    NANOPHARMA AS CZ (PARDUBICE) participant 9˙000.00
10    EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ EE (TARTU) participant 0.00
11    Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus BY (Minsk) partner 0.00

Map

 Project objective

The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order to minimize dimensions and simplify the use of the detection system. The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization, bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs via new scientific papers and conference theses and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.

 Deliverables

List of deliverables.
ALD metal oxide (ZnO and ZnO/Al2O3 nanolaminates) and metal oxide/Au nanostructures deposited on 1D nanofibers templates with tailored structural (grain size, thickness, crystalline structure, etc.) and optical properties (absorption and emission bands, b Documents, reports 2020-03-18 18:59:04
Functionalized 1D metal oxide nanostructures with tailored functional groups Documents, reports 2020-03-18 18:59:04
Cultivated cancer cell lines and proved specificity between the cancer cells and antibodies Documents, reports 2020-03-18 18:59:04
Fundamental structural and optical properties of ALD deposited metal oxide (ZnO and ZnO/Al2O3 nanolaminates) and metal oxide/Au nanostructures deposited on 1D nanofibers templates: single metal oxide layer thickness influence to amorphous-to-crystalline t Documents, reports 2020-03-18 18:59:04
Developed web page of the project Websites, patent fillings, videos etc. 2020-03-18 18:59:03
1D organic (PAN, gelatine, PLA, HA, etc.) nanofibers templates deposited by electrospinning with defined structural properties Documents, reports 2020-03-18 18:59:03

Take a look to the deliverables list in detail:  detailed list of CanBioSe deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Uldis Malinovskis, Raimonds Poplausks, Donats Erts, Kerstin Ramser, Sigitas Tamulevičius, Asta Tamulevičienė, Yesong Gu, Juris Prikulis
High-Density Plasmonic Nanoparticle Arrays Deposited on Nanoporous Anodic Alumina Templates for Optical Sensor Applications
published pages: 531, ISSN: 2079-4991, DOI: 10.3390/nano9040531
Nanomaterials 9/4 2020-04-24
2019 Valerii Myndrul, Igor Iatsunskyi
Nanosilicon-Based Composites for (Bio)sensing Applications: Current Status, Advantages, and Perspectives
published pages: 2880, ISSN: 1996-1944, DOI: 10.3390/ma12182880
Materials 12/18 2020-04-24
2019 Anton Popov, Arunas Stirke, Neringa Bakute, Benediktas Brasiunas, Arunas Ramanavicius, Almira Ramanaviciene
Efficiency of granulocyte colony-stimulating factor immobilized on magnetic microparticles on proliferation of NFS-60 cells
published pages: 123580, ISSN: 0927-7757, DOI: 10.1016/j.colsurfa.2019.123580
Colloids and Surfaces A: Physicochemical and Engineering Aspects 578 2020-04-24
2019 Margarita Baitimirova, Jana Andzane, Roman Viter, Bernard Fraisse, Octavio Graniel, Mikhael Bechelany, John Watt, Domantas Peckus, Sigitas Tamulevicius, Donats Erts
Improved Crystalline Structure and Enhanced Photoluminescence of ZnO Nanolayers in Bi 2 Se 3 /ZnO Heterostructures
published pages: 31156-31166, ISSN: 1932-7447, DOI: 10.1021/acs.jpcc.9b08417
The Journal of Physical Chemistry C 123/51 2020-04-24
2019 Roman Viter, Kwanele Kunene, Povilas Genys, Daniels Jevdokimovs, Donats Erts, Andris Sutka, Krishna Bisetty, Arturs Viksna, Almira Ramanaviciene, Arunas Ramanavicius
Photoelectrochemical Bisphenol S Sensor Based on ZnO‐Nanoroads Modified by Molecularly Imprinted Polypyrrole
published pages: 1900232, ISSN: 1022-1352, DOI: 10.1002/macp.201900232
Macromolecular Chemistry and Physics 221/2 2020-04-24
2019 Matthieu Weber, Jin-Young Kim, Jae-Hyoung Lee, Jae-Hun Kim, Igor Iatsunskyi, Emerson Coy, Philippe Miele, Mikhael Bechelany, Sang Sub Kim
Highly efficient hydrogen sensors based on Pd nanoparticles supported on boron nitride coated ZnO nanowires
published pages: 8107-8116, ISSN: 2050-7488, DOI: 10.1039/c9ta00788a
Journal of Materials Chemistry A 7/14 2020-04-24
2019 Octavio Graniel, Igor Iatsunskyi, Emerson Coy, Christophe Humbert, Grégory Barbillon, Thierry Michel, David Maurin, Sébastien Balme, Philippe Miele, Mikhael Bechelany
Au-covered hollow urchin-like ZnO nanostructures for surface-enhanced Raman scattering sensing
published pages: 15066-15073, ISSN: 2050-7534, DOI: 10.1039/c9tc05929f
Journal of Materials Chemistry C 7/47 2020-04-24
2019 Weber, Graniel, Balme, Miele, Bechelany
On the Use of MOFs and ALD Layers as Nanomembranes for the Enhancement of Gas Sensors Selectivity
published pages: 1552, ISSN: 2079-4991, DOI: 10.3390/nano9111552
Nanomaterials 9/11 2020-04-24
2020 Emerson Coy, Katarzyna Siuzdak, Mykola Pavlenko, Karol Załęski, Octavio Graniel, Marcin Ziółek, Sebastien Balme, Philippe Miele, Matthieu Weber, Mikhael Bechelany, Igor Iatsunskyi
Enhancing photocatalytic performance and solar absorption by schottky nanodiodes heterojunctions in mechanically resilient palladium coated TiO2/Si nanopillars by atomic layer deposition
published pages: 123702, ISSN: 1385-8947, DOI: 10.1016/j.cej.2019.123702
Chemical Engineering Journal 392 2020-04-24
2020 Mehmet Turemis, Daniele Zappi, Maria Teresa Giardi, Giovanni Basile, Almira Ramanaviciene, Aleksandrs Kapralovs, Arunas Ramanavicius, Roman Viter
ZnO/polyaniline composite based photoluminescence sensor for the determination of acetic acid vapor
published pages: 120658, ISSN: 0039-9140, DOI: 10.1016/j.talanta.2019.120658
Talanta 211 2020-03-18
2019 Roman Viter, Maryna Savchuk, Nickolay Starodub, Zigmas Balevicius, Saulius Tumenas, Almira Ramanaviciene, Daniels Jevdokimovs, Donats Erts, Igor Iatsunskyi, Arunas Ramanavicius
Photoluminescence immunosensor based on bovine leukemia virus proteins immobilized on the ZnO nanorods
published pages: 601-606, ISSN: 0925-4005, DOI: 10.1016/j.snb.2019.01.054
Sensors and Actuators B: Chemical 285 2020-03-18
2019 Alexander Tamashevski, Yuliya Harmaza, Roman Viter, Daniels Jevdokimovs, Raimond Poplausks, Ekaterina Slobozhanina, Lina Mikoliunaite, Donats Erts, Almira Ramanaviciene, Arunas Ramanavicius
Zinc oxide nanorod based immunosensing platform for the determination of human leukemic cells
published pages: 378-386, ISSN: 0039-9140, DOI: 10.1016/j.talanta.2019.03.064
Talanta 200 2020-03-18
2018 Y. Harmaza, A. Tamashevski, D. Jevdokimovs, R. Viter, E. Slobozhanina
The membrane toxicology of rods and spheric zinc oxide nanoparticles
published pages: S206, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.905
Toxicology Letters 295 2020-03-18
2018 Octavio Graniel, Viktoriia Fedorenko, Roman Viter, Igor Iatsunskyi, Grzegorz Nowaczyk, Matthieu Weber, Karol Załęski, Stefan Jurga, Valentyn Smyntyna, Philippe Miele, Arunas Ramanavicius, Sebastien Balme, Mikhael Bechelany
Optical properties of ZnO deposited by atomic layer deposition (ALD) on Si nanowires
published pages: 139-146, ISSN: 0921-5107, DOI: 10.1016/j.mseb.2018.11.007
Materials Science and Engineering: B 236-237 2020-03-18
2018 Harmaza Y., Tamashevski A., Viter R., Slobozhanina E.
Photoluminescent zinc oxide nanorods – a new tool for detection of human leukemic cells
published pages: , ISSN: , DOI:
HemaSphere Vol. 2, S1 2020-03-18
2018 Octavio Graniel, Matthieu Weber, Sébastien Balme, Philippe Miele, Mikhael Bechelany
Atomic layer deposition for biosensing applications
published pages: 147-159, ISSN: 0956-5663, DOI: 10.1016/j.bios.2018.09.038
Biosensors and Bioelectronics 122 2020-03-18

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