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Deciphering of Root and Rhizosphere microbiome to increase host fitness in the Fusarium oxysporum- plant interaction

Total Cost €


EC-Contrib. €






 DIRECTION project word cloud

Explore the words cloud of the DIRECTION project. It provides you a very rough idea of what is the project "DIRECTION" about.

proportion    interplay    wilt    vascular    synthetic    threat    isogenic    immune    23    rhizosphere    endophytic    pathogenic    sustainable    provoke    generate    fungal    lab    plant    pathogens    pyrosequencing    carry    chain    interaction    syncom    outcompete    modulating    reassemble    extensive    benign    model    fungus    microbial    chemical    soil    taxonomically    pesticides    tomato    provokes    competitors    microbiota    signalling    advancing    assays    losses    disease    identification    devastating    microbes    communities    agriculture    sensing    pathogen    annually    crops    health    infecting    microbiome    oxysporum    human    barcoded    mutants    sophisticated    actively    borne    huge    molecularly    caused    strategies    vivo    serious    platform    yield    suppress    effect    colonizing    colonization    antagonistic    fusarium    nutrition    root    exerting    collection    fox    world    hundred    dissect    bacterial    insights    agricultural    unsustainable    food    fungi    thereby    destroying    dataset    host   

Project "DIRECTION" data sheet

The following table provides information about the project.


Organization address
postcode: 14005

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE CORDOBA ES (CORDOBA) coordinator 170˙121.00


 Project objective

Fungi have a devastating impact on human nutrition and health. Fungal pathogens provoke huge yield losses in crops, destroying around 23% of the agricultural production annually. A major proportion of this loss is caused by pathogenic root-colonizing microbes that have evolved sophisticated strategies to outcompete the benign microbial competitors in the rhizosphere and to actively suppress the plant immune response. The fungal pathogen Fusarium oxysporum (Fox) is a soil-borne root infecting fungus that provokes vascular wilt disease in over a hundred different agricultural crops, and represents a serious threat world-wide. The current control methods for this pathogen depend upon extensive use of chemical pesticides, which are highly unsustainable in the food-chain. Here we propose to use the Fox-tomato interaction as a model to molecularly dissect the role of the root (including endophytic) and rhizosphere microbiota in modulating vascular wilt disease. We will use a barcoded pyrosequencing approach to taxonomically define the root and rhizosphere microbiome in tomato. Next, we will dissect the impact of the microbiome on fungal host sensing, using an established collection of isogenic signalling mutants of Fox available in the host lab. We will carry out in vivo Fox- bacterial interaction assays to generate a dataset for identification of bacterial communities exerting an antagonistic effect on pathogen colonization. The project will thus produce new insights into the interplay between the root microbiome and pathogen colonization. The, generated knowledge platform will be used to reassemble a synthetic ‘SynCom’ microbiome that will be used to control Vascular Wilt, thereby advancing the development of sustainable agriculture.

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The information about "DIRECTION" are provided by the European Opendata Portal: CORDIS opendata.

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