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BRAIN CAMO SIGNED

Camouflaging electronics in the brain with immobilized liquid coatings

Total Cost €

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EC-Contrib. €

0

Partnership

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 BRAIN CAMO project word cloud

Explore the words cloud of the BRAIN CAMO project. It provides you a very rough idea of what is the project "BRAIN CAMO" about.

water    insulation    probes    fronts    adherence    coatings    environment    brain    fibrous    underlying    treat    degrade    fail    epilepsy    material    chemistry    comprised    materials    exceed    neural    organic    bare    healthcare    date    applicable    capsule    billion    multiple    stimulating    mechanical    ilcs    disorders    45    majority    encapsulation    mismatch    depression    parkinson    interfacing    shield    immobilized    performance    surface    uk    shields    neuronal    million    approximately    probe    euros    implantable    immiscible    electronics    barrier    chronic    cells    immune    metal    inflammation    crack    alone    reducing    polymer    evaluations    liquids    gel    invaluable    130    utilized    vast    stiffness    proteins    area    vivo    induce    solely    promotes    introducing    flexible    recording    anchored    tools    insulating    shown    suffering    silicon    tissue    biocompatibility    organics    death    tissues    gt    liquid    surrounding    strategy    expose   

Project "BRAIN CAMO" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 183˙454.00

Map

 Project objective

In the UK alone, those suffering from brain disorders is approximately 45 million and associated healthcare costs exceed 130 billion euros per year. Neural electronics for recording and stimulating brain activity have become invaluable tools to study and treat disorders such as epilepsy, depression, and Parkinson’s. Currently used neural probes often fail in chronic evaluations (>1 year); the stiffness and chemistry of probes induce inflammation, neuronal death, and fibrous capsule formation. When examining a neural probe, the vast majority of the surface area is comprised of the encapsulation material; an insulating polymer that shields electronics from tissue. To date, most studies of implantable electronics have utilized only bare insulation as the tissue-interfacing material, yet in long-term studies, these insulation materials degrade and crack from the in vivo environment and expose the underlying electronics. Furthermore, adherence of proteins and cells to insulation promotes the immune response against the probe. Therefore, introducing an effective barrier between insulation and tissue is a highly promising approach for improving probe biocompatibility and performance. In this proposal, the approach is to use water-immiscible liquids anchored to the surface by a gel to shield neural probes from surrounding tissue. The proposed strategy of these immobilized liquid coatings (ILCs) is applicable to all implantable electronics, including those for other tissues and those based on various materials (silicon, metal, and organics). This proposal will focus solely on organic probes, which can be flexible and have recently been shown to improve biocompatibility by the reducing the mechanical mismatch between probe and brain tissue. Therefore, applying ILCs to organic neural probes will advance the current state-of-the-art and will address chronic biocompatibility on multiple fronts.

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The information about "BRAIN CAMO" are provided by the European Opendata Portal: CORDIS opendata.

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