Opendata, web and dolomites

sigNal SIGNED

Novel insights into the sensing of salt stress in plants: understanding the relationship between salt stress response and cytosolic pH changes.

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 sigNal project word cloud

Explore the words cloud of the sigNal project. It provides you a very rough idea of what is the project "sigNal" about.

experimental    toxic    prevents    protein    concentration    paradigm    responsible    sensing    stress    determinants    sensor    thr    imaging    dependent    calcium    activated    components    salt    criteria    abiotic    sodicity    hypothesis    provokes    na    levels    prof    partition    fluorescence    initiate    messenger    alkaline    signalling    kinase    ser    additional    overly    sos1    postdoct    sos2    demonstrated    signals    existence    plants    sensitive    perceives    regulates    salinity    alkalinisation    learned    roots    plant    pm    core    signature    ca    meet    visualisation    localisations    posit    subcellular    schumacher    triggered    input    experiments    variety    activates    cells    stage    duiring    ratio    shoots    sos3    accumulation    technics    free    cytosolic    phosphorylation    antiporter    shift    stresses    structural    activate    induce    recruits    localized    intracellular    sos    group    homeostasis    signal    interactions    mechanisms    ph    integrate    relaying    sensed    regulatory   

Project "sigNal" data sheet

The following table provides information about the project.

Coordinator
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG 

Organization address
address: SEMINARSTRASSE 2
city: HEIDELBERG
postcode: 69117
website: www.uni-heidelberg.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 171˙460 €
 EC max contribution 171˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG DE (HEIDELBERG) coordinator 171˙460.00

Map

 Project objective

The Salt Overly Sensitive (SOS) pathway is one of the main regulatory systems responsible for Na homeostasis in plants. The SOS pathway is activated by salt stress and comprises three core components: SOS1, SOS2 and SOS3. SOS3 is a calcium (Ca) sensor that perceives the increase of intracellular Ca triggered by salt stress and recruits SOS2, a Ser/Thr protein kinase, to the PM. The complex activates protein SOS1 by phosphorylation, a PM-localized Na/H antiporter that prevents the accumulation of Na to toxic levels and regulates Na partition between roots and shoots. Cytosolic free Ca is a common second messenger in the signalling of a variety of abiotic stresses. The wide range of Ca-activated responses lead us to posit the existence of additional mechanisms relaying input signals that, together with this Ca signature, would initiate the specific response for a particular stress. The hypothesis of my proposal is that the increase in intracellular Na concentration provokes the alkalinisation of the intracellular pH, what would be sensed by SOS3. SOS3 would work as pH and Ca sensor, which would integrate this pH shift and the Ca signature to activate SOS pathway.

To support the hypothesis of cytosolic alkalinisation as a salt stress signal and SOS3 as a Ca and pH sensor, two experimental criteria must be meet: (1) salinity should induce an alkaline pH shift in plant cells, and (2) structural determinants of pH-sensing should be demonstrated in SOS3. To achieve my goal: (1) I will use a system, improved by Prof. Schumacher’s group, which allows the visualisation of pH changes in selected subcellular localisations through fluorescence ratio imaging experiments; and (2) I will use the technics learned and used duiring my postdoct stage to study whether SOS3 interactions and/or activity are pH dependent.

This research will provide a new paradigm of how sodicity is sensed by plant cells.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SIGNAL" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SIGNAL" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

ACES (2019)

Antarctic Cyclones: Expression in Sea Ice

Read More  

POSPORI (2019)

Polymer Optical Sensors for Prolonged Overseeing the Robustness of civil Infrastructures

Read More  

INSPiRE (2018)

The Influence of Information Search on Preference Formation and Choice

Read More