Opendata, web and dolomites
H2020 projects about "kinase"
The page lists 100 projects related to the topic "kinase".
| # | |||
|---|---|---|---|
| 1 | Phosphoprocessors | Biological signal processing via multisite phosphorylation networks | 2015 |
| 2 | CVDTEU | Clinical validation of the DiviTum assay in key European markets | 2014 |
| 3 | TRYP-QS | YAK kinase regulated trypanosome quorum sensing | 2015 |
| 4 | FAST-RAP | Structure-function studies of the human FASTK family of mitochondrial proteins with putative novel RNA binding domains – the helical FAST motifs and the small RAP domain | 2015 |
| 5 | Syncrip_2014 | The molecular basis of learning and memory: uncovering the link between neuronal activation and localized translation at the synapse. | 2015 |
| 6 | MoTOR | Analysis of the “moonlighting” proteins in the mTOR-signalling pathway | 2016 |
| 7 | Class II PI3K | Characterization of the signalling and physiological roles of the class II PI3Ks | 2016 |
| 8 | ROR2BONE | Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling | 2015 |
| 9 | OSS | Spatio-temporal control of the Src kinase activation through Optogenetics in Cell invasion | 2016 |
| 10 | MELANOPARK | Investigating the LRRK2-melanin connection through phosphoproteomics of isogenic melanoma cells | 2015 |
| 11 | AND | Antibacterial (Nano)medicines Development | 2015 |
| 12 | RECOLOR | Regulation and consequences of LRRK2 phosphorylation,a path to Parkinson’s disease therapy and diagnostics | 2015 |
| 13 | TITLY | Inhibition of the T-cell receptor signalling pathway for treatment of T-cell lymphoma | 2015 |
| 14 | PFSEXOME | Identification of protein kinases and signalling pathways important for Plasmodium falciparum malaria transmission | 2015 |
| 15 | HepatoRiSK | A new tumor suppressor role for RSK2 in hepatocellular carcinoma | 2015 |
| 16 | CARDIOTOX | Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology | 2015 |
| 17 | SENSITIVITYMARKERS | Clinical validation of prognostic biomarkers of chemotherapy response in liquid biopsies | 2015 |
| 18 | ER_disease | Defining hormonal cross-talk and the role of mutations in estrogen receptor positive breast cancer | 2015 |
| 19 | LEONID | Lung cancEr fusiOn geNes: a new dIagnostic Device | 2015 |
| 20 | TRIGGDRUG | Reactions That Translate mRNA into Drug-like Molecules | 2016 |
| 21 | AUROMYC | N-Myc and Aurora A: From Protein Stability to Chromosome TopologyN-Myc and Aurora A: From Protein Stability to Chromosome TopologyMyc and Aurora A: From Protein Stability to Chromosome Topology | 2015 |
| 22 | Phd | Deciphering PI3K biology in health and disease | 2015 |
| 23 | ALKATRAS | ALK Activation as a target of TRAanslational Science (ALKATRAS): Break free from cancer | 2015 |
| 24 | PROTEOMICS4D | Proteomics 4D: The proteome in context | 2015 |
| 25 | NutrientSensingVivo | The Physiology of Nutrient Sensing by mTOR | 2016 |
| 26 | BIOVALID | Clinical validation of the DiviTum assay in two high profile clinical studies in Europe | 2015 |
| 27 | UNIBIO | TK210 ELISA – universal serum protein biomarker for cancer screening, diagnosis, treatment response monitoring and early detection of relapse (UNIBIO) | 2015 |
| 28 | GvHDCure | Understanding the dynamics of the immune system to cure graft-versus-host disease (GvHD). | 2016 |
| 29 | LDC4PCaTher | BMX-targeted ligand-drug conjugates for prostate cancer therapy | 2016 |
| 30 | MCNTMTDC | Metabolic control on NF-κB activity during dendritic cells-mediated immune tolerance to tumours | 2017 |
| 31 | PrecTherLSCC | Precision Therapies in Lung Squamous Cell Carcinoma | 2016 |
| 32 | SKINFRET | The involvement of epidermal stem cells in spatiotemporal ERK activity propagation | 2016 |
| 33 | NuSiCC | Modelling the therapeutic potential of NUAK1 suppression in colorectal cancer | 2016 |
| 34 | PIM PROTEOMICS | Unravelling PIM kinase signal integration in the T cell response | 2017 |
| 35 | MECHANOCHECK | ATR-mediated mechanotransduction and connections with the actin cytoskeleton | 2016 |
| 36 | ENVERESP | Crosstalk between nuclear envelope and DNA Damage Response: Role of nucleoporin TPR in the maintenance of genomic integrity | 2016 |
| 37 | STrkB | The structural biology of TrkB-BDNF signalling | 2017 |
| 38 | GeneREFORM | Genetically Encoded Multicolor Reporter Systems For Multiplexed MRI | 2016 |
| 39 | ONCOINTRABODY | Targeting common oncogenes with intracellular monobodies | 2016 |
| 40 | 2MoveMate4Melanoma | A treatment for BRAF inhibitor resistant melanoma | 2016 |
| 41 | pArg_deg_signal | No stress with pArg: Mechanisms of a distinct phospho-mark to coordinate stress response and protein quality control | 2016 |
| 42 | NEUROMET | Shaping of axonal complexity by a dynamic regulation of local metabolic pathways in the developing cortex | 2016 |
| 43 | LeukaemiaTargeted | Selecting genetic lesions with essential function for patients' leukaemia in vivo as targets for precision medicine | 2016 |
| 44 | CDK6-DrugOpp | CDK6 in transcription - turning a foe in a friend | 2016 |
| 45 | LYSOTRACK | Defining the role of lysosomal trafficking in age-associated anabolic resistance in human skeletal muscle | 2016 |
| 46 | ACENTSPINTUB | Setting up the spindle in the mammalian egg for meiosis and embryo development | 2017 |
| 47 | TKI resistance | Resistance mechanisms to tyrosine kinase inhibitors in solid tumors | 2016 |
| 48 | LungCARD | Blood test for clinical therapy guidance of non-small cell lung cancer patients | 2017 |
| 49 | AMPK-DIAB | A small molecule AMP activated protein kinase (AMPK) activator, denoted O304, as a novelinnovative drug for the treatment of type 2 diabetes | 2016 |
| 50 | GlycoModels | 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management | 2017 |
| 51 | CoALIVE | Coenzyme A – Launch of In Vivo Experiments | 2017 |
| 52 | RepliStressTiming | Impact of replicative stress on DNA replication timing control | 2017 |
| 53 | BRAINHIB | Integrated drug discovery approach to generate brain-penetrant inhibitors of glioblastoma cell proliferation | 2018 |
| 54 | PHOSPH-UBIQ-IMMUN | Dynamic interplay between phosphorylation and ubiquitination during plant receptor kinase-mediated immunity | 2017 |
| 55 | TRIBBLES | Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma | 2018 |
| 56 | MSCFate | Fate of mammary stem cells during tumorigenesis and clinical implications | 2017 |
| 57 | PCAGED-KI | Photocaged Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Diseases | 2017 |
| 58 | IVORIaN | RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. | 2017 |
| 59 | INSPirAUTOR | Understanding how Inositol Polyphosphates regulate autophagy and lipid body formation in photosynthetic organisms: crosstalk with TOR signaling. | 2018 |
| 60 | DUALITY | An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors | 2018 |
| 61 | PI3K-VAs | Activation of PI3K signalling in the pathogenesis of Vascular Anomalies | 2018 |
| 62 | ChAMPioN | Game-changing Precision Medicine for Curing All Myeloproliferative Neoplasms | 2018 |
| 63 | onCOMBINE | Towards evidence-based combinations of approved and novel cancer drugs | 2017 |
| 64 | TRIPLECON | Triple negative breast cancer control through synergistic inhibition of EGFR and CDK9 signaling | 2017 |
| 65 | REVERSEAUTISM | Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models | 2017 |
| 66 | AutoClean | Cell-free reconstitution of autophagy to dissect molecular mechanisms | 2018 |
| 67 | Alpha-Synuclein | Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. | 2019 |
| 68 | REMIX | Effects of rewiring microexons (REMIX) on tissue-specific signaling networks | 2018 |
| 69 | IMMUNO-PEPTALK | Regulation of plant receptor kinase-mediated immunity by endogenous peptides and their receptors | 2018 |
| 70 | sigNal | Novel insights into the sensing of salt stress in plants: understanding the relationship between salt stress response and cytosolic pH changes. | 2018 |
| 71 | Za-AV | Determination of physiologically relevant RNA substrate(s) and design of small-molecule inhibitors for Zα domains as potential intervention strategies for viral infections and autoimmunity | 2018 |
| 72 | MitoScaling | Mitotic scaling to cell size diversity during vertebrate embryonic development | 2019 |
| 73 | ONCOTHERANOSTICS | Advanced Theranostic Nanomedicines for Oncology. Development of new combinatorial therapies for primary and metastatic Breast Cancer. | 2019 |
| 74 | COAGULANT | CK2-dependent cytoskeletal regulation and molecular signaling of Neutrophil Extracellular Trap (NET) formation | 2018 |
| 75 | SPArKLE | New players in immunometabolism: investigating the role of succinate and pyruvate kinase in T cell immunity | 2018 |
| 76 | RET PHOTOSWITCH | THE DEVELOPMENT OF NOVEL PHOTOSWITCHABLE KINASE INHIBITORS | 2018 |
| 77 | OCOCAMKS | Optical control of CaMKII signaling | 2018 |
| 78 | SelectiveTGFb-inhib | Pro-tumorigenic effects of TGFb - elucidation of mechanisms and development of selective inhibitors | 2018 |
| 79 | Oncogenic PI3-kinase | New biology of oncogenic PI 3-kinase | 2019 |
| 80 | PI3K MODULATORS | Identification and characterisation of new class of PI3K modulators in oncology | 2019 |
| 81 | MINT | Multifunctional Immunocompatible NanoTheranostics to modulate tumor microenvironment and improve treatment monitoring: A double blow to pancreatic cancer | 2019 |
| 82 | STOPFOP | Saracatinib Trial tO Prevent FOP | 2019 |
| 83 | TENDO | Tension of ENDOmembranes maintained by TORC1 | 2019 |
| 84 | LYSOKIN | Architecture and regulation of PI3KC2β lipid kinase complex for nutrient signaling at the lysosome | 2020 |
| 85 | MS4Drug | An Innovative Mass Spectrometry-Based Workflow for Drug Discovery | 2019 |
| 86 | ABA-GrowthBalance | Growth balance regulation by SnRK1 under ABA-stress conditions | 2019 |
| 87 | IBL-302 | Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer | 2019 |
| 88 | EPICAN | Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer | 2020 |
| 89 | KINETICfinder | KINETICfinder: A disruptive method to determine kinetic profiles in drug discoveries | 2019 |
| 90 | PI3K-in-tolerance | PI3K delta role in dendritic cell antigen processing and presentation to control gut tolerance | 2019 |
| 91 | TOPAS | Exploiting the Tumor Proteome Activity Status for Future Cancer Therapies | 2019 |
| 92 | MetaboSENS | Metabolic integration by nutrient SENSing | 2019 |
| 93 | CSI AurkA-MYC | Conformational Shift Inducers (CSI): An atomistic level investigation of Aurora kinase A (AurkA)–MYC interaction and its distortion by CSI compounds | 2019 |
| 94 | ISOLDA | Improved Vaccination Strategies for Older Adults | 2020 |
| 95 | PDPcardio | Protein phosphatase 1-disrupting peptides: Scope and mechanism of action in the treatment of heart insufficiency | 2020 |
| 96 | TOR in acTIon | TRANSLATION INITIATION CONTROL IN PLANTS: THE ROLE OF TOR (TARGET OF RAPAMYCIN) | 2020 |
| 97 | MITafterVIT | Unravelling maintenance mechanisms of immune tolerance after termination of venom immunotherapy by means of clonal mast cell diseases | 2020 |
| 98 | Irrev Fork Arrest | Deciphering the mechanism of irreversible replication fork arrest | 2020 |
| 99 | ObeSIK3 | Role of SIK3 in energy homeostasis | 2021 |
| 100 | TARGETOF | Mass cytometry nanotools for intracellular target engagement. Towards precision medicine. | 2021 |