Opendata, web and dolomites


Evolution of supergenes and the genetic basis of snail colour polymorphism

Total Cost €


EC-Contrib. €






 SUPEREVOL project word cloud

Explore the words cloud of the SUPEREVOL project. It provides you a very rough idea of what is the project "SUPEREVOL" about.

trait    phenotypic    prominent    recombination    resource    researcher    pave    extensive    animal    biodiversity    inversions    bioinformatics    supergenes    locus    species    morphological    tight    evolutionary    natural    isolation    helping    clusters    professional    biology    single    panoply    track    offers    characters    genetic    crosses    re    poorly    uncovering    shell    nearly    presumably    hot    fill    land    surprisingly    community    supergene    advantage    play    linkage    genetics    basis    behavioural    polymorphism    controls    myself    sequencing    maturity    speciation    window    transferable    scarce    maintenance    association    populations    reproductive    me    developmental    laboratory    evolution    valuable    genomic    multiple    analytical    despite    coloration    ago    cepaea    combining    snail    discrete    nemoralis    components    individual    record    expand    polymorphisms    suppress    climate    molecular    loci    model    dna    mapping    architecture    adaptive    fellowship    inherited    genomics    sequence    scientific    emergence    existence    assemble    gap    chromosomal    physical    breakthroughs    helps    ecological    genome    provides    skills    phenotypes    host    colour   

Project "SUPEREVOL" data sheet

The following table provides information about the project.


Organization address
address: DARWINWEG 2
city: LEIDEN
postcode: 2333CR

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The concept of a supergene, proposed nearly 80 years ago, has become a hot topic in biology. Supergenes are clusters of several loci, each affecting a different morphological or behavioural trait; tight physical linkage and chromosomal inversions suppress recombination so that multiple phenotypic characters are inherited as a single locus. Supergenes play a crucial role in the maintenance of highly discrete adaptive phenotypes, eventually leading to reproductive isolation and speciation. Despite the panoply of complex polymorphisms presumably controlled by supergenes, molecular evidence for their existence is scarce, and the emergence of such genetic architecture is surprisingly poorly understood. The proposed project helps to fill this scientific gap by investigating the supergene that controls shell colour polymorphism in a classical model for ecological genetics and climate-induced evolutionary change, the land snail Cepaea nemoralis. In particular, I will 1) sequence and assemble the genome of C. nemoralis, and 2) identify the individual components of its supergene by linkage mapping in laboratory crosses and association mapping in natural populations. I will do this by taking advantage of the most recent technical breakthroughs in DNA sequencing and bioinformatics. Combining my extensive knowledge of animal coloration with my host laboratory's track record in biodiversity research and genomics, this project offers a unique window into the evolution of supergenes and polymorphisms and provides the European research community with a valuable genomic resource. By uncovering the molecular basis of C. nemoralis supergene I will establish this species as a prominent European model in evolutionary developmental biology. This fellowship will not only allow me to expand my technical and analytical skills, but also enhance my transferable skills, helping me to re-establish myself as a researcher and pave a path through which I will reach professional maturity.

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The information about "SUPEREVOL" are provided by the European Opendata Portal: CORDIS opendata.

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