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SUPEREVOL SIGNED

Evolution of supergenes and the genetic basis of snail colour polymorphism

Total Cost €

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EC-Contrib. €

0

Partnership

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 SUPEREVOL project word cloud

Explore the words cloud of the SUPEREVOL project. It provides you a very rough idea of what is the project "SUPEREVOL" about.

provides    analytical    fill    bioinformatics    sequence    physical    snail    polymorphisms    existence    morphological    supergenes    molecular    biodiversity    emergence    developmental    populations    nemoralis    trait    polymorphism    coloration    helps    poorly    ecological    individual    phenotypes    land    record    window    genetics    surprisingly    assemble    me    colour    characters    controls    adaptive    inversions    genomic    resource    dna    advantage    breakthroughs    genome    association    biology    maintenance    components    community    track    evolutionary    play    scientific    laboratory    reproductive    animal    valuable    nearly    expand    shell    recombination    climate    loci    speciation    helping    basis    despite    cepaea    chromosomal    panoply    discrete    fellowship    transferable    pave    suppress    sequencing    single    prominent    architecture    species    model    isolation    genetic    phenotypic    researcher    maturity    myself    ago    locus    hot    re    multiple    evolution    presumably    genomics    uncovering    mapping    supergene    behavioural    crosses    combining    clusters    professional    extensive    inherited    host    natural    skills    scarce    linkage    offers    tight    gap   

Project "SUPEREVOL" data sheet

The following table provides information about the project.

Coordinator
STICHTING NATURALIS BIODIVERSITY CENTER 

Organization address
address: DARWINWEG 2
city: LEIDEN
postcode: 2333CR
website: www.naturalis.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING NATURALIS BIODIVERSITY CENTER NL (LEIDEN) coordinator 177˙598.00

Map

 Project objective

The concept of a supergene, proposed nearly 80 years ago, has become a hot topic in biology. Supergenes are clusters of several loci, each affecting a different morphological or behavioural trait; tight physical linkage and chromosomal inversions suppress recombination so that multiple phenotypic characters are inherited as a single locus. Supergenes play a crucial role in the maintenance of highly discrete adaptive phenotypes, eventually leading to reproductive isolation and speciation. Despite the panoply of complex polymorphisms presumably controlled by supergenes, molecular evidence for their existence is scarce, and the emergence of such genetic architecture is surprisingly poorly understood. The proposed project helps to fill this scientific gap by investigating the supergene that controls shell colour polymorphism in a classical model for ecological genetics and climate-induced evolutionary change, the land snail Cepaea nemoralis. In particular, I will 1) sequence and assemble the genome of C. nemoralis, and 2) identify the individual components of its supergene by linkage mapping in laboratory crosses and association mapping in natural populations. I will do this by taking advantage of the most recent technical breakthroughs in DNA sequencing and bioinformatics. Combining my extensive knowledge of animal coloration with my host laboratory's track record in biodiversity research and genomics, this project offers a unique window into the evolution of supergenes and polymorphisms and provides the European research community with a valuable genomic resource. By uncovering the molecular basis of C. nemoralis supergene I will establish this species as a prominent European model in evolutionary developmental biology. This fellowship will not only allow me to expand my technical and analytical skills, but also enhance my transferable skills, helping me to re-establish myself as a researcher and pave a path through which I will reach professional maturity.

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The information about "SUPEREVOL" are provided by the European Opendata Portal: CORDIS opendata.

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