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SUPEREVOL SIGNED

Evolution of supergenes and the genetic basis of snail colour polymorphism

Total Cost €

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EC-Contrib. €

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Partnership

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 SUPEREVOL project word cloud

Explore the words cloud of the SUPEREVOL project. It provides you a very rough idea of what is the project "SUPEREVOL" about.

ago    scarce    emergence    helping    multiple    characters    panoply    track    speciation    scientific    populations    colour    transferable    valuable    chromosomal    discrete    single    dna    bioinformatics    architecture    play    morphological    crosses    model    laboratory    fill    physical    snail    genetics    natural    suppress    sequence    locus    individual    isolation    animal    myself    ecological    reproductive    shell    polymorphism    existence    adaptive    basis    trait    polymorphisms    recombination    skills    controls    maturity    species    behavioural    offers    resource    surprisingly    genome    genomics    climate    advantage    nemoralis    uncovering    developmental    assemble    provides    genomic    cepaea    me    inversions    analytical    pave    expand    inherited    record    nearly    coloration    mapping    breakthroughs    presumably    evolutionary    phenotypic    evolution    land    sequencing    window    host    tight    fellowship    components    molecular    researcher    gap    hot    clusters    despite    extensive    poorly    community    biology    loci    combining    linkage    prominent    supergenes    biodiversity    maintenance    phenotypes    helps    professional    genetic    association    supergene    re   

Project "SUPEREVOL" data sheet

The following table provides information about the project.

Coordinator
STICHTING NATURALIS BIODIVERSITY CENTER 

Organization address
address: DARWINWEG 2
city: LEIDEN
postcode: 2333CR
website: www.naturalis.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING NATURALIS BIODIVERSITY CENTER NL (LEIDEN) coordinator 177˙598.00

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 Project objective

The concept of a supergene, proposed nearly 80 years ago, has become a hot topic in biology. Supergenes are clusters of several loci, each affecting a different morphological or behavioural trait; tight physical linkage and chromosomal inversions suppress recombination so that multiple phenotypic characters are inherited as a single locus. Supergenes play a crucial role in the maintenance of highly discrete adaptive phenotypes, eventually leading to reproductive isolation and speciation. Despite the panoply of complex polymorphisms presumably controlled by supergenes, molecular evidence for their existence is scarce, and the emergence of such genetic architecture is surprisingly poorly understood. The proposed project helps to fill this scientific gap by investigating the supergene that controls shell colour polymorphism in a classical model for ecological genetics and climate-induced evolutionary change, the land snail Cepaea nemoralis. In particular, I will 1) sequence and assemble the genome of C. nemoralis, and 2) identify the individual components of its supergene by linkage mapping in laboratory crosses and association mapping in natural populations. I will do this by taking advantage of the most recent technical breakthroughs in DNA sequencing and bioinformatics. Combining my extensive knowledge of animal coloration with my host laboratory's track record in biodiversity research and genomics, this project offers a unique window into the evolution of supergenes and polymorphisms and provides the European research community with a valuable genomic resource. By uncovering the molecular basis of C. nemoralis supergene I will establish this species as a prominent European model in evolutionary developmental biology. This fellowship will not only allow me to expand my technical and analytical skills, but also enhance my transferable skills, helping me to re-establish myself as a researcher and pave a path through which I will reach professional maturity.

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The information about "SUPEREVOL" are provided by the European Opendata Portal: CORDIS opendata.

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