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Evolution of supergenes and the genetic basis of snail colour polymorphism

Total Cost €


EC-Contrib. €






 SUPEREVOL project word cloud

Explore the words cloud of the SUPEREVOL project. It provides you a very rough idea of what is the project "SUPEREVOL" about.

loci    extensive    populations    biodiversity    scientific    assemble    trait    isolation    phenotypes    valuable    controls    resource    pave    community    dna    advantage    phenotypic    model    physical    polymorphisms    molecular    genetics    components    myself    inherited    individual    climate    host    biology    provides    mapping    species    transferable    animal    despite    track    genome    emergence    panoply    land    breakthroughs    combining    association    hot    helping    architecture    locus    suppress    existence    cepaea    nearly    bioinformatics    speciation    colour    sequence    behavioural    offers    recombination    linkage    fill    genetic    maintenance    record    snail    supergenes    presumably    poorly    analytical    nemoralis    skills    evolutionary    adaptive    developmental    play    characters    discrete    ago    evolution    uncovering    basis    natural    supergene    sequencing    crosses    coloration    helps    prominent    reproductive    shell    me    scarce    single    morphological    professional    genomic    ecological    fellowship    chromosomal    researcher    polymorphism    surprisingly    window    tight    laboratory    expand    genomics    gap    re    multiple    inversions    maturity    clusters   

Project "SUPEREVOL" data sheet

The following table provides information about the project.


Organization address
address: DARWINWEG 2
city: LEIDEN
postcode: 2333CR

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The concept of a supergene, proposed nearly 80 years ago, has become a hot topic in biology. Supergenes are clusters of several loci, each affecting a different morphological or behavioural trait; tight physical linkage and chromosomal inversions suppress recombination so that multiple phenotypic characters are inherited as a single locus. Supergenes play a crucial role in the maintenance of highly discrete adaptive phenotypes, eventually leading to reproductive isolation and speciation. Despite the panoply of complex polymorphisms presumably controlled by supergenes, molecular evidence for their existence is scarce, and the emergence of such genetic architecture is surprisingly poorly understood. The proposed project helps to fill this scientific gap by investigating the supergene that controls shell colour polymorphism in a classical model for ecological genetics and climate-induced evolutionary change, the land snail Cepaea nemoralis. In particular, I will 1) sequence and assemble the genome of C. nemoralis, and 2) identify the individual components of its supergene by linkage mapping in laboratory crosses and association mapping in natural populations. I will do this by taking advantage of the most recent technical breakthroughs in DNA sequencing and bioinformatics. Combining my extensive knowledge of animal coloration with my host laboratory's track record in biodiversity research and genomics, this project offers a unique window into the evolution of supergenes and polymorphisms and provides the European research community with a valuable genomic resource. By uncovering the molecular basis of C. nemoralis supergene I will establish this species as a prominent European model in evolutionary developmental biology. This fellowship will not only allow me to expand my technical and analytical skills, but also enhance my transferable skills, helping me to re-establish myself as a researcher and pave a path through which I will reach professional maturity.

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The information about "SUPEREVOL" are provided by the European Opendata Portal: CORDIS opendata.

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