Explore the words cloud of the LANTERNS project. It provides you a very rough idea of what is the project "LANTERNS" about.
The following table provides information about the project.
UNIVERSIDAD AUTONOMA DE MADRID
|Coordinator Country||Spain [ES]|
|Total cost||158˙121 €|
|EC max contribution||158˙121 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2019-05-01 to 2021-04-30|
Take a look of project's partnership.
|1||UNIVERSIDAD AUTONOMA DE MADRID||ES (MADRID)||coordinator||158˙121.00|
This project aims to address the current limitations of existing in vivo optical imaging nanoprobes (ONPs). Specifically, the present study targets a tangible breakthrough that will increase both the optical contrast and sub-tissue penetration depth of optical imaging, compared to that obtainable with state-of-the art contrast agents. In particular, the ability to optically overcome the limitations imposed by autofluorescence (light endogenously generated by the specimen upon irradiation) constitutes a very demanding requirement for the real-life application of ONPs. In LANTERNS my proposal is to accomplish the above-mentioned goals through an elegant marriage between lanthanide (Ln) ions and chalcogenide ternary quantum dots (QDs), the latter acting as a host for the ions. These smartly-designed ONPs (Ln-QDs) will have a superior capability for minimally-invasive deep-tissue imaging, owing to an unprecedented brightness and fully near-infrared (NIR) operational capabilities. These features will endow the so-designed Ln-QDs with outstanding optical contrast and sub-tissue penetration depth. In perspective, the development of this system will deliver an all-optical diagnostic practice that will reduce patient risk, in terms of possible harm, and lessen the amount of radiation required to localize malignancies. These goals will be achieved concurrently with a considerable reduction of the imaging costs via the use of low-cost excitation sources and signal detection setups, also shortening the imaging times. The project is also expected to lead to the assessment of a widely applicable method to produce a virtually infinite number of Ln-QDs, whose optical properties could be finely tuned throughout the entire optical radiation spectrum. Beyond the main biomedical aim of this project, the expected progress will constitute a significant leap within the luminescent materials science field, with an appeal to a broad scientific community.
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The information about "LANTERNS" are provided by the European Opendata Portal: CORDIS opendata.
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