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MAPoPHAGY SIGNED

Maturation of plant autophagosomes: mapping the route to sustainability

Total Cost €

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EC-Contrib. €

0

Partnership

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 MAPoPHAGY project word cloud

Explore the words cloud of the MAPoPHAGY project. It provides you a very rough idea of what is the project "MAPoPHAGY" about.

schumacher    delivered    fecundity    oscillations    cells    career    host    regulating    biogenesis    vesicles    eating    organelles    tools    traits    damaged    networks    lytic    molecules    world    degradation    content    environment    ten    greek    expertise    expert    renowned    assembly    specialized    fundamental    plant    scholar    uncharted    morphology    tolerance    limited    undetectable    invasive    autophagosomes    mutual    outstanding    membrane    maturing    sensitivity    self    autophagic    broaden    compartment    site    territory    strengthen    degrade    destined    recycle    organism    catabolic    stress    join    autophagy    cargo    became    benefit    impacts    markedly    expand    pathogen    removes    exchange    skills    tracking    molecular    line    longevity    contribution    route    break    perform    trafficking    biochemistry    establishing    map    reputation    resistance    luminescence    detection    systematic    dynamic    eukaryotic    superfluous    prof    time    vacuole    fitness    first    unfortunately    previously    mechanism    planta    harmful    scientific   

Project "MAPoPHAGY" data sheet

The following table provides information about the project.

Coordinator
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG 

Organization address
address: SEMINARSTRASSE 2
city: HEIDELBERG
postcode: 69117
website: www.uni-heidelberg.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 171˙460 €
 EC max contribution 171˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-09-21   to  2020-09-20

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG DE (HEIDELBERG) coordinator 171˙460.00

Map

 Project objective

Autophagy (from the Greek for “self eating”) is a catabolic process, by which eukaryotic cells degrade and recycle their content. This mechanism removes superfluous, damaged or harmful molecules or organelles and thus greatly impacts fitness of the organism. Autophagic cargo destined for degradation is delivered to the lytic compartment by specialized vesicles, autophagosomes. As of yet, the path from the plant autophagosomes assembly site to the lytic vacuole is uncharted territory. The first objective of this project is to perform a systematic study investigating the dynamic changes in morphology and biochemistry of the plant maturing autophagosomes and creating a molecular map of their route towards the lytic vacuole. This knowledge will be a fundamental contribution to the plant autophagy and plant membrane trafficking research fields. Autophagy is involved in regulating plant longevity, fecundity, stress tolerance and pathogen resistance. Unfortunately, our understanding of its role in establishing these traits is limited by the autophagy detection tools currently available. In this project I will establish the first high sensitivity luminescence-based non-invasive system for in planta detection of autophagic activity. This approach will be a break-through, as it will finally allow real-time in planta tracking of previously undetectable oscillations of autophagic activity throughout plant development under variable conditions. During the past ten years I became an expert in plant autophagy research. My host, Prof. Schumacher, is a world renowned scholar in plant membrane trafficking and lytic vacuole biogenesis. Mutual exchange of our expertise will greatly benefit the project, expand our skills and broaden our scientific networks. Furthermore, this project is a very important step in my career development, as I will join a new field of studies, work in a new scientific environment with an outstanding reputation and markedly strengthen my line of research.

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The information about "MAPOPHAGY" are provided by the European Opendata Portal: CORDIS opendata.

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