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MAPoPHAGY SIGNED

Maturation of plant autophagosomes: mapping the route to sustainability

Total Cost €

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EC-Contrib. €

0

Partnership

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 MAPoPHAGY project word cloud

Explore the words cloud of the MAPoPHAGY project. It provides you a very rough idea of what is the project "MAPoPHAGY" about.

unfortunately    previously    oscillations    membrane    luminescence    map    regulating    break    undetectable    host    skills    scientific    systematic    autophagy    world    vesicles    self    fecundity    molecular    join    traits    prof    outstanding    impacts    uncharted    damaged    sensitivity    exchange    time    planta    degradation    trafficking    content    specialized    invasive    first    ten    maturing    fundamental    harmful    limited    contribution    expert    delivered    removes    biogenesis    mechanism    networks    compartment    schumacher    plant    perform    mutual    morphology    autophagosomes    stress    lytic    expand    cargo    eukaryotic    became    biochemistry    tracking    degrade    superfluous    reputation    environment    resistance    broaden    route    renowned    catabolic    tolerance    markedly    career    line    benefit    vacuole    fitness    autophagic    pathogen    organelles    dynamic    cells    scholar    recycle    eating    assembly    destined    organism    greek    strengthen    territory    longevity    expertise    establishing    site    tools    detection    molecules   

Project "MAPoPHAGY" data sheet

The following table provides information about the project.

Coordinator
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG 

Organization address
address: SEMINARSTRASSE 2
city: HEIDELBERG
postcode: 69117
website: www.uni-heidelberg.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 171˙460 €
 EC max contribution 171˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-09-21   to  2020-09-20

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG DE (HEIDELBERG) coordinator 171˙460.00

Map

 Project objective

Autophagy (from the Greek for “self eating”) is a catabolic process, by which eukaryotic cells degrade and recycle their content. This mechanism removes superfluous, damaged or harmful molecules or organelles and thus greatly impacts fitness of the organism. Autophagic cargo destined for degradation is delivered to the lytic compartment by specialized vesicles, autophagosomes. As of yet, the path from the plant autophagosomes assembly site to the lytic vacuole is uncharted territory. The first objective of this project is to perform a systematic study investigating the dynamic changes in morphology and biochemistry of the plant maturing autophagosomes and creating a molecular map of their route towards the lytic vacuole. This knowledge will be a fundamental contribution to the plant autophagy and plant membrane trafficking research fields. Autophagy is involved in regulating plant longevity, fecundity, stress tolerance and pathogen resistance. Unfortunately, our understanding of its role in establishing these traits is limited by the autophagy detection tools currently available. In this project I will establish the first high sensitivity luminescence-based non-invasive system for in planta detection of autophagic activity. This approach will be a break-through, as it will finally allow real-time in planta tracking of previously undetectable oscillations of autophagic activity throughout plant development under variable conditions. During the past ten years I became an expert in plant autophagy research. My host, Prof. Schumacher, is a world renowned scholar in plant membrane trafficking and lytic vacuole biogenesis. Mutual exchange of our expertise will greatly benefit the project, expand our skills and broaden our scientific networks. Furthermore, this project is a very important step in my career development, as I will join a new field of studies, work in a new scientific environment with an outstanding reputation and markedly strengthen my line of research.

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The information about "MAPOPHAGY" are provided by the European Opendata Portal: CORDIS opendata.

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