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ElectroGene SIGNED

Electrogenetics – Shaping Electrogenetic Interfaces for Closed-Loop Voltage-Controlled Gene Expression

Total Cost €


EC-Contrib. €






 ElectroGene project word cloud

Explore the words cloud of the ElectroGene project. It provides you a very rough idea of what is the project "ElectroGene" about.

preclinical    capitalizing    wearable    contrast    advent    multicellular    simultaneously    molecular    direct    differently    share    networks    block    things    ecosystem    limited    reactions    onset    lenses    optogenetic    central    diabetes    metal    multicore    volatile    implants    diagnostics    remote    slow    human    wireless    frequency    cells    complexity    time    designer    bioelectronics    science    genetically    made    man    metabolism    disease    dosing    prevention    signals    soluble    protein    ion    electro    treatment    therapeutics    electronics    gradients    gigahertz    flow    analog    metabolic    electrons    electrogene    uses    loop    electrogenetics    full    harnessing    units    vision    consists    communication    mind    radically    pillars    principles    validated    connections    voltage    gene    google    bioelectronic    living    glucose    monitoring    interconnected    profile    powered    membranes    communicate    genetic    physical    internet    insulated    biological    heartbeat    diagnosis    electronic    smartphone    closed    programmed    wave    medical    wired    adjustable    incompatible    proof    drug    wires    foundations    implanted    largely    chemical    expression    interfaces    contact    therapy    triggered    linking   

Project "ElectroGene" data sheet

The following table provides information about the project.


Organization address
address: Raemistrasse 101
postcode: 8092

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 2˙500˙000 €
 EC max contribution 2˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-ADG
 Funding Scheme ERC-ADG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Man and man-made electronic systems share the same ecosystem, and yet work radically differently. Human metabolism uses ion gradients across insulated membranes to simultaneously process slow analog chemical reactions and communicate information in multicellular systems via soluble/volatile molecular signals. By contrast, electronic systems use multicore central processing units to control the flow of electrons through insulated metal wires with gigahertz frequency and communicate information across networks via wired/wireless connections. With the advent of the internet of things, networks of interconnected electronic devices will reach the processing complexity of living systems, yet they remain largely incompatible with biological systems. Wearable electronics can profile physical parameters such as steps and heartbeat, and Google’s proposal to develop glucose-monitoring contact lenses has triggered a wave of interest in harnessing the full potential of bioelectronics for medical applications. Yet this vision remains limited to diagnostics. Capitalizing on our mind-controlled and smartphone-adjustable optogenetic drug-dosing devices, ElectroGene will establish the foundations of electrogenetics, the science of creating electro-genetic interfaces that enable direct two-way communication between electronic devices and living cells. ElectroGene consists of three pillars, (i) voltage-triggered gene expression, (ii) genetically programmed electronics and (iii) wireless-powered implants providing closed-loop bioelectronic control, which allow real-time monitoring of metabolic conditions (diagnosis), enable remote-controlled production and dosing of protein therapeutics by implanted designer cells (treatment), and manage closed-loop control between cells and electronics, thus linking diagnosis and therapy to block disease onset (prevention). ElectroGene design principles and devices will be validated in proof-of-concept preclinical studies for the treatment of diabetes.

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The information about "ELECTROGENE" are provided by the European Opendata Portal: CORDIS opendata.

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