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HELPHERGEN SIGNED

THE GENETIC BASIS OF MATING BEHAVIOR: PHEROMONE COMMUNICATION IN NOCTUID MOTHS

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HELPHERGEN project word cloud

Explore the words cloud of the HELPHERGEN project. It provides you a very rough idea of what is the project "HELPHERGEN" about.

genetic    genome    bioinformatic    map    excellent    crispr    skills    multidisciplinary    behavioral    knock    rituals    evolution    signals    wild    evolutionary    attraction    biology    degree    dramatic    gene    supervisor    males    roles    ibed    innovative    females    multivariate    collaborative    reveal    assays    regimes    correlated    architecture    fitness    differential    expression    mating    functional    mate    combines    genotype    uva    cutting    share    variation    biodiversity    engineering    ecosystem    examine    dynamics    experiments    interdisciplinary    host    poorly    trait    behavior    cas9    inevitably    university    amsterdam    framework    female    quantitative    sexes    reproductive    pleiotropy    behaviors    phenotypic    communication    edge    secondment    scripting    noctuid    covary    integrating    idiosyncratic    techniques    phenotype    animal    sex    candidate    headway    effect    pheromone    genes    traits    courtship    male    lab    editing    training    moths    lines   

Project "HELPHERGEN" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT VAN AMSTERDAM 

Organization address
address: SPUI 21
city: AMSTERDAM
postcode: 1012WX
website: www.uva.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-12-13

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) coordinator 177˙598.00

Map

 Project objective

The genetic architecture of behavior is a major topic in biology, but remains poorly understood. The behaviors with the most dramatic effect on animal fitness are those involved in mate attraction and courtship, which are directly related to reproductive success. Males and females share a genome but have idiosyncratic roles in courtship rituals; mating traits thus experience sex-specific selection regimes. Variation at the gene expression level can facilitate sex-specific trait evolution to some degree. However, sex-specific traits inevitably covary, leading to correlated evolutionary responses (pleiotropy). Here I propose an innovative and multidisciplinary framework integrating a quantitative genetic approach to multivariate phenotypic evolution with functional genetic experiments. The key objective is to reveal how genes controlling traits involved in mating behavior can have widespread phenotypic effects across sexes by quantitative genetic measurements of pheromone communication variation in wild-type and knock-out lines of noctuid moths. I will examine the correlated evolution of pheromone signals in male and female moths and identify candidate genes using differential expression analyses. Then, I will examine the phenotypic effects using the cutting-edge CRISPR/Cas9 system and a quantitative genetic framework to test behavioral effects. The proposed research combines behavioral, quantitative genetic, and gene editing techniques and will make headway towards understanding the genotype-phenotype map of mating behavior. I will be based at the Institute for Biodiversity and Ecosystem Dynamics (IBED), an excellent interdisciplinary research institute focusing on functional biodiversity at the University of Amsterdam (UvA). Via training-through-research and a secondment at a collaborative lab of the host supervisor, I will learn essential, state-of-the-art skills including genetic engineering, gene expression assays, and advanced bioinformatic scripting.

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The information about "HELPHERGEN" are provided by the European Opendata Portal: CORDIS opendata.

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