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Pan3DP SIGNED

3D bioprinting of pancreatic tissue for biomedical research

Total Cost €

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EC-Contrib. €

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Partnership

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Project "Pan3DP" data sheet

The following table provides information about the project.

Coordinator
KING'S COLLEGE LONDON 

Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS
website: www.kcl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 3˙000˙000 €
 EC max contribution 3˙000˙000 € (100%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-1-2016-2017
 Funding Scheme RIA
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2021-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 788˙865.00
2    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) participant 572˙500.00
3    TEL AVIV UNIVERSITY IL (TEL AVIV) participant 483˙750.00
4    DE DUVE INSTITUTE BE (BRUXELLES) participant 421˙250.00
5    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 381˙250.00
6    POIETIS FR (PESSAC) participant 352˙385.00

Map

 Project objective

Developing therapies for pancreatic diseases, such as diabetes and pancreatic cancer, is hampered by a limited access to pancreatic tissue in vivo. Engineering three-dimensional (3D) tissue models, which accurately mimic the native organ, have great potential in biomedical applications, by both providing powerful platforms for studying tissue development and homeostasis and for modeling diseases in pharmaceutical testing. Our research proposal establishes a multi-disciplinary European consortium with the ambitious goal of developing an innovative bioprinting approach for generating pancreatic tissue. Tissues and organs comprise multiple cell types with specific biological functions that must be recapitulated in the printed tissue. We will biomimic developmental processes to fabricate 3D bioprinted pancreatic tissue units that allow sustained cell viability, expansion and functional differentiation ex vivo. Specifically, the aim of this proposal is three-fold: 1. To expand and unify the knowledge of 3D in vivo architecture of the developing pancreas; 2. To develop bioprinting technology for engineering vascularized pancreatic tissue units; and 3. To establish conditions for in vitro differentiation and maturation of the bioprinted pancreatic tissue. This exploratory research in the emerging technological field of bioprinting will pave the way towards new technological possibilities of growing functional tissues and organs in a laboratory. We expect that the knowledge and paradigms generated by our research project will not only drive major technological advances in tissue-engineering and bioprinting, but will also open radically new possibilities in medicine, allowing to study pancreatic diseases ex vivo in fabricated tissue, to develop new drugs, and, possibly to facilitate the replacement of injured or diseased tissue.

 Deliverables

List of deliverables.
Dissemination WP1 Websites, patent fillings, videos etc. 2020-02-13 13:12:30
Consortium workshops I Websites, patent fillings, videos etc. 2020-02-13 13:10:10
Consortium website Websites, patent fillings, videos etc. 2020-02-13 13:10:35
Definition of each cell population in the pancreas Documents, reports 2020-02-13 13:10:24

Take a look to the deliverables list in detail:  detailed list of Pan3DP deliverables.

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The information about "PAN3DP" are provided by the European Opendata Portal: CORDIS opendata.

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