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Sea4Pain SIGNED

Development of a novel analgesic for chronic pain from marine-derived compounds

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

Sea4Pain project word cloud

Explore the words cloud of the Sea4Pain project. It provides you a very rough idea of what is the project "Sea4Pain" about.

disruptive 2015 applies discovery drugs acting founded 525 action demonstrated suffer inflict shows opioid life strategy channels population worth world drive kv marine patented 51 38 pharmaceuticals extremely received grants compounds global differentiated neurons modulator constantly quality billion co fifth capital 2022 ease habituation portuguese severe toxicity team compound biomedicine chronic series give adverse sea4pain huge switch analgesic first supporting sea4us brain 13 limited drug alternative 2013 treatments channel professionals roll class raised cagr health addiction modulate venture market 4 derivate sensing pathologies benefits breakthroughs patients efficacy suffering biotechnological innovative 250 crowdfunding noxious pharmaceutical lab expand moderate alleviate platform pain derivatives ion mode

Project "Sea4Pain" data sheet

The following table provides information about the project.

Coordinator	SEA4US BIOTECNOLOGIA E RECURSOS MARINHOS LDA Organization address address: RUA DO POENTE S/N city: SAGRES postcode: 8650 378 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Portugal [PT]
Project website	http://sea4us.pt/en/
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2018
Duration (year-month-day)	from 2018-05-01 to 2018-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SEA4US BIOTECNOLOGIA E RECURSOS MARINHOS LDA SEA4US BIOTECNOLOGIA E RECURSOS MARINHOS LDA Organization address address: RUA DO POENTE S/N city: SAGRES postcode: 8650 378 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (SAGRES)	coordinator	50˙000.00

Map

Project objective

'The Sea4Pain project will expand and define the development strategy for Sea4Us’s “Drug Discovery and Development Platform” – a platform that applies novel biotechnological approaches to exploit marine derived compounds for the development of novel pharmaceuticals highly relevant for biomedicine. The first lab-based research results have clearly demonstrated the benefits of marine compounds in a series of pathologies, like chronic pain, and the huge potential of its derivate products in the health market. In particular, our innovative breakthroughs will lead to the development of a unique, high efficacy analgesic (ion channel modulator), with reduced toxicity and limited side-effects (Sea4Pain). This extremely innovative approach shows a differentiated mode-of-action (acting directly in the 'pain switch'), that will give rise to a new class of pharmaceutical drugs with no expected adverse effects on the brain (currently being patented). The disruptive compound will modulate specific ion channels in pain-sensing neurons (Kv), for which there is no known modulator, and ease the suffering of one fifth of the World's population who constantly suffer from chronic pain. Sea4Pain will offer alternative treatments for patients suffering from moderate to severe chronic pain. Current drugs in the market (opioid derivatives and others) do alleviate pain but co-inflict important noxious effects (habituation, addiction, loss of drive) and great loss in quality of life. The global pain management drugs and devices market was estimated to be worth $38 billion in 2015 and reach $51 billion in 2022 at a CAGR of 4%. Founded in 2013, Sea4Us has received over 525.000€ in Portuguese and European Research Grants, raised 10.000€ with crowdfunding, and 250.000€ in venture capital, supporting a team of 13 professionals and is focused on developing the Sea4Pain roll-to-market of innovative treatments.'

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The information about "SEA4PAIN" are provided by the European Opendata Portal: CORDIS opendata.