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Penetration-promoting and Imageable Polymeric Micelles as a Platform Technology for Individualized and Improved Tumor-targeted Drug Delivery

Total Cost €


EC-Contrib. €






Project "PIcelles" data sheet

The following table provides information about the project.


Organization address
address: Pauwelsstrasse 30
city: AACHEN
postcode: 52074

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

PIcelles will assess the commercial viability of a novel theranostic nanoformulation for anticancer therapy. Current nanomedicine platforms are not able to boost response rates and survival times due to two main reasons: (1) the high variability in the accumulation of nanomedicines in tumors and metastases; and (2) the poor tissue penetration of nanomedicines in tumors and metastases. Based on results of the ERC project NeoNaNo, we are developing an imageable and penetration-promoting PIcelles platform, which is based on polymeric micelles, that will tackle these challenges by incorporating three key features in one formulation: (1) chelators for radiolabeling, to enable patient pre-selection via non-invasive imaging of target site accumulation; (2) a novel peptide on the micelles’ shell, to allow for active targeting to the microenvironment in tumors and metastases, and also for active pharmacological promotion of nanomedicine penetration; and (3) facile, efficient and stable drug loading, with clinically relevant anticancer agents.

In this project, we aim to generate technical and commercial proof-of-concept for our proprietary PIcelles platform technology, enabling us to enter into license deals with large pharmaceutical industries that are in need of novel breakthrough drug delivery technologies for their difficult-to-formulate anticancer agents.

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The information about "PICELLES" are provided by the European Opendata Portal: CORDIS opendata.

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