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MuFLOART SIGNED

Microbiological fluorescence observatory for antibiotic resistance tracking

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MuFLOART project word cloud

Explore the words cloud of the MuFLOART project. It provides you a very rough idea of what is the project "MuFLOART" about.

drug    labeled    quality    antimicrobial    microbes    quantification    battery    minimising    uk    metabolic    footprints    small    fluorescently    population    interactions    susceptibility    area    datasets    stressful    solar    lightweight    antibiotics    environments    geographically    traits    mediate    evolution    phenotypic    microbial    create    deployment    populations    biology    mean    positive    optimise    adapt    virulence    standardisation    dose    prototypes    screens    perform    computer    resistance    data    power    seeking    functions    pipelines    afford    microbiology    algorithms    finalise    phenotypes    multiple    communities    tests    settings    hard    accurate    genes    biotechnology    phenotyping    team    erc    evolve    teaching    science    critical    schools    profiles    rates    synergy    individuality    gene    evolutionary    hardware    efficiencies    deprived    turn    rationales    antibiotic    either    device    throughput    heterogeneity    expression    photometry    assays    laboratory    mathematics    benefit    hospital   

Project "MuFLOART" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 149˙249 €
 EC max contribution 149˙249 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 149˙249.00

Map

 Project objective

The accurate quantification of microbial populations is critical for understanding how microbes evolve and adapt to stressful environments. This, in turn, can help improve rationales for drug deployment aimed at minimising the evolution of antibiotic resistance. Working on ERC-funded research into how microbial communities optimise their virulence traits and mediate drug-resistance, our team identified a need for a low cost photometry device capable of high-throughput quantification of microbial phenotypes such as microbial growth rates and metabolic efficiencies; microbial dose responses and susceptibility to antibiotics; antibiotic interactions datasets; microbial individuality and heterogeneity data and population mean gene expression profiles for fluorescently labeled genes. There are multiple positive consequences of having these capabilities at low cost: we can create high-throughput data pipelines for microbiology research, particularly for evolutionary studies or phenotypic screens; we can improve the dissemination of high-quality phenotypic data analysis algorithms (such as synergy tests for antibiotics) and so provide standardisation for those phenotypic assays; schools can benefit from the low-costs laboratory hardware and bring data analysis for microbiology into their mathematics, biology or computer science teaching; our lightweight devices with small footprints can be used to access geographically hard-to-reach areas where drug resistance phenotyping could be conducted using either battery or solar power. We are, therefore, now in the process of creating two prototypes that can perform these functions and we are seeking funding to finalise their design and field test the devices in three different settings: a partner research laboratory studying microbial evolution, a hospital research laboratory studying antimicrobial resistance and finally schools in a top-10 deprived area of the UK that cannot afford biotechnology equipment for teaching science.

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The information about "MUFLOART" are provided by the European Opendata Portal: CORDIS opendata.

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