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MuFLOART SIGNED

Microbiological fluorescence observatory for antibiotic resistance tracking

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MuFLOART project word cloud

Explore the words cloud of the MuFLOART project. It provides you a very rough idea of what is the project "MuFLOART" about.

finalise    quantification    lightweight    uk    pipelines    evolve    laboratory    hard    geographically    evolutionary    mean    microbiology    standardisation    communities    datasets    science    small    evolution    synergy    gene    interactions    afford    genes    teaching    drug    assays    prototypes    susceptibility    deployment    antimicrobial    mathematics    functions    data    quality    phenotypic    expression    phenotypes    hardware    tests    schools    stressful    biology    heterogeneity    adapt    accurate    efficiencies    optimise    area    seeking    power    hospital    throughput    computer    deprived    multiple    populations    profiles    minimising    critical    resistance    battery    metabolic    create    erc    biotechnology    footprints    traits    settings    microbial    rationales    virulence    solar    positive    benefit    algorithms    population    perform    antibiotics    screens    rates    turn    team    antibiotic    dose    environments    device    individuality    phenotyping    microbes    photometry    mediate    fluorescently    labeled    either   

Project "MuFLOART" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 149˙249 €
 EC max contribution 149˙249 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 149˙249.00

Map

 Project objective

The accurate quantification of microbial populations is critical for understanding how microbes evolve and adapt to stressful environments. This, in turn, can help improve rationales for drug deployment aimed at minimising the evolution of antibiotic resistance. Working on ERC-funded research into how microbial communities optimise their virulence traits and mediate drug-resistance, our team identified a need for a low cost photometry device capable of high-throughput quantification of microbial phenotypes such as microbial growth rates and metabolic efficiencies; microbial dose responses and susceptibility to antibiotics; antibiotic interactions datasets; microbial individuality and heterogeneity data and population mean gene expression profiles for fluorescently labeled genes. There are multiple positive consequences of having these capabilities at low cost: we can create high-throughput data pipelines for microbiology research, particularly for evolutionary studies or phenotypic screens; we can improve the dissemination of high-quality phenotypic data analysis algorithms (such as synergy tests for antibiotics) and so provide standardisation for those phenotypic assays; schools can benefit from the low-costs laboratory hardware and bring data analysis for microbiology into their mathematics, biology or computer science teaching; our lightweight devices with small footprints can be used to access geographically hard-to-reach areas where drug resistance phenotyping could be conducted using either battery or solar power. We are, therefore, now in the process of creating two prototypes that can perform these functions and we are seeking funding to finalise their design and field test the devices in three different settings: a partner research laboratory studying microbial evolution, a hospital research laboratory studying antimicrobial resistance and finally schools in a top-10 deprived area of the UK that cannot afford biotechnology equipment for teaching science.

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The information about "MUFLOART" are provided by the European Opendata Portal: CORDIS opendata.

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