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MuFLOART SIGNED

Microbiological fluorescence observatory for antibiotic resistance tracking

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MuFLOART project word cloud

Explore the words cloud of the MuFLOART project. It provides you a very rough idea of what is the project "MuFLOART" about.

positive    labeled    hospital    seeking    evolve    data    lightweight    drug    efficiencies    microbes    hard    datasets    assays    traits    throughput    profiles    standardisation    expression    biotechnology    footprints    hardware    environments    dose    antimicrobial    population    deployment    geographically    biology    photometry    afford    mean    quality    interactions    microbial    individuality    mathematics    gene    settings    mediate    synergy    stressful    optimise    functions    teaching    phenotyping    antibiotics    virulence    uk    communities    resistance    rationales    computer    quantification    laboratory    either    power    small    microbiology    fluorescently    turn    solar    minimising    benefit    erc    evolutionary    prototypes    phenotypes    evolution    populations    critical    antibiotic    finalise    screens    create    battery    metabolic    science    rates    algorithms    susceptibility    accurate    multiple    device    phenotypic    adapt    deprived    heterogeneity    pipelines    team    area    schools    tests    genes    perform   

Project "MuFLOART" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 149˙249 €
 EC max contribution 149˙249 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 149˙249.00

Map

 Project objective

The accurate quantification of microbial populations is critical for understanding how microbes evolve and adapt to stressful environments. This, in turn, can help improve rationales for drug deployment aimed at minimising the evolution of antibiotic resistance. Working on ERC-funded research into how microbial communities optimise their virulence traits and mediate drug-resistance, our team identified a need for a low cost photometry device capable of high-throughput quantification of microbial phenotypes such as microbial growth rates and metabolic efficiencies; microbial dose responses and susceptibility to antibiotics; antibiotic interactions datasets; microbial individuality and heterogeneity data and population mean gene expression profiles for fluorescently labeled genes. There are multiple positive consequences of having these capabilities at low cost: we can create high-throughput data pipelines for microbiology research, particularly for evolutionary studies or phenotypic screens; we can improve the dissemination of high-quality phenotypic data analysis algorithms (such as synergy tests for antibiotics) and so provide standardisation for those phenotypic assays; schools can benefit from the low-costs laboratory hardware and bring data analysis for microbiology into their mathematics, biology or computer science teaching; our lightweight devices with small footprints can be used to access geographically hard-to-reach areas where drug resistance phenotyping could be conducted using either battery or solar power. We are, therefore, now in the process of creating two prototypes that can perform these functions and we are seeking funding to finalise their design and field test the devices in three different settings: a partner research laboratory studying microbial evolution, a hospital research laboratory studying antimicrobial resistance and finally schools in a top-10 deprived area of the UK that cannot afford biotechnology equipment for teaching science.

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The information about "MUFLOART" are provided by the European Opendata Portal: CORDIS opendata.

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