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FunHoMic SIGNED

Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections

Total Cost €

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EC-Contrib. €

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Partnership

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 FunHoMic project word cloud

Explore the words cloud of the FunHoMic project. It provides you a very rough idea of what is the project "FunHoMic" about.

interventions    ecology    edge    risk    clinical    cutting    profiles    netherlands    frequently    population    france    host    health    fatal    forefront    broad    women    depends       translational    smes    13    metabolites    modulators    pathogenesis    severity    immune    vulvovaginal    time    esrs    gastro    training    plus    uk    polymorphisms    interplay    episode    tract    infection    belgium    skills    chip    medical    impose    switzerland    billion    thrush    innovative    fungal    patient    germany    markers    vision    integrates    simulation    strain    human    individual    precision    economic    candidiasis    initiation    genetic    spain    unrivalled    hospital    enduring    microbiota    organ    medicine    intestinal    stage    train    platforms    candida    cancer    experts    microbial    burden    academic    preventive    technologies    people    serious    oral    biotherapeutic    recurrent    funhomic    gain    intricate    status    sectoral    species    therapeutic    first    display    bloodstream    antifungals    mindset    french    immunology    killing    mycology    biomarkers    acquired    live    inter    unites    expertise    omics    infections    variability    malaria    lbps    pave    infecting    interdisciplinary    stratification    breast    vaginitis    suffered   

Project "FunHoMic" data sheet

The following table provides information about the project.

Coordinator
INSTITUT PASTEUR 

Organization address
address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724
website: http://www.pasteur.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 3˙530˙871 €
 EC max contribution 3˙530˙871 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT PASTEUR FR (PARIS CEDEX 15) coordinator 549˙604.00
2    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN UK (ABERDEEN) participant 606˙345.00
3    LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT DE (JENA) participant 505˙576.00
4    UNIVERSITAT ZURICH CH (ZURICH) participant 281˙276.00
5    BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE FR (LYON) participant 274˙802.00
6    BIOSE FR (ARPAJON SUR CERE) participant 274˙802.00
7    MIMETAS BV NL (Leiden) participant 265˙619.00
8    STICHTING KATHOLIEKE UNIVERSITEIT NL (NIJMEGEN) participant 265˙619.00
9    PRODIGEST BE (GENT ZWIJNAARDE) participant 256˙320.00
10    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) participant 250˙904.00
11    EVOTEC (UK) LIMITED UK (ABINGDON OXFORDSHIRE) partner 0.00
12    FRIEDRICH-SCHILLER-UNIVERSITAT JENA DE (JENA) partner 0.00
13    UNIVERSIDAD AUTONOMA DE BARCELONA ES (CERDANYOLA DEL VALLES) partner 0.00
14    UNIVERSITE CLERMONT AUVERGNE FR (CLERMONT-FERRAND) partner 0.00
15    UNIVERSITE PARIS DESCARTES FR (PARIS CEDEX 06) partner 0.00
16    UNIVERSITE PARIS DIDEROT - PARIS 7 FR (PARIS) partner 0.00
17    UNIVERSITEIT GENT BE (GENT) partner 0.00
18    UNIVERSITEIT LEIDEN NL (LEIDEN) partner 0.00

Map

 Project objective

Fungal infections have a major impact on human health, infecting about 2 billion people and killing more people each year than malaria or breast cancer. In particular, Candida species impose a high clinical and economic burden upon the European population. They frequently cause fatal hospital-acquired bloodstream infections. They also cause oral thrush and vaginitis. Most women have suffered an episode of vulvovaginal candidiasis, with ~8% enduring recurrent infections. The initiation and severity of a Candida infection depends on an intricate interplay between the infecting fungal strain and the individual’s immune status and microbiota, all of which can display significant variability. Therefore, for the first time, FunHoMic integrates experts in fungal pathogenesis, immunology, microbial ecology and ‘omics technologies to train 13 Early Stage Researchers (ESRs) who will define and exploit this Fungal-Host-Microbiota interplay to identify novel biomarkers (fungal or host genetic polymorphisms, microbiota profiles, metabolites or immune markers) for the stratification of a patient’s risk of serious fungal infection. This will pave the way for precision medicine in patient management through preventive or therapeutic interventions using antifungals, immune modulators or Live Biotherapeutic Products (LBPs). FunHoMic ESRs will gain broad interdisciplinary skills plus a translational mindset through our integrated, inter-sectoral training program. This will allow Europe to remain at the forefront of translational research in the field of medical mycology. To achieve this vision FunHoMic unites academic partners from France, Germany, The Netherlands, Switzerland, Spain and UK, a French Technology Research Institute with cutting-edge ‘omics technology platforms and three SMEs from The Netherlands, Belgium and France that bring unrivalled organ-on-chip and gastro-intestinal tract simulation technologies and expertise in the development and exploitation of innovative LBPs.

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The information about "FUNHOMIC" are provided by the European Opendata Portal: CORDIS opendata.

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