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Enabling Large-Scale GMP-ready Peptide Production with a new, reliable and cost-efficient Bioprocess

Total Cost €


EC-Contrib. €






 NUMA-SCALE project word cloud

Explore the words cloud of the NUMA-SCALE project. It provides you a very rough idea of what is the project "NUMA-SCALE" about.

material    ip    creation    upscale    jobs    environmentally    peptides    ton    employability    competent    mission    revenues    downstream    founded    commercial    gmp    innovative    extend    companies    scalable    certain    safe    numa    relatively    gained    50x    approved    block    manufacture    insulin    carbon    foot    amounts    contract    patented    generate    length    14    alternatives    practices    2015    economical    8m    good    therapeutics    massive    efficiency    human    drugs    transfer    gt    bad    compliant    company    ready    biomolecules    diseases    numaferm    selective    peptide    seize    markets    facilities    numaswitch    pharmaceutical    compromises    german    numatag    raw    tackle    upstream    limitation    15    efficacious    tolerated    technologies    manufacturing    market    successfully    tech    2023    venture    90    ones    escalate    treating    business    scalability    print    boost    metabolism    efficient    positive    sugar   

Project "NUMA-SCALE" data sheet

The following table provides information about the project.


Organization address
postcode: 40225
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2019-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NUMAFERM GMBH DE (DUSSELDORF) coordinator 50˙000.00


 Project objective

Peptides, competent biomolecules, have gained increased interest as innovative therapeutics in the pharmaceutical market due to being highly selective, efficacious, relatively safe and well tolerated. Peptide-based drugs have been successfully applied in treating certain human diseases. Well-known example includes insulin, which compromises a peptide that is built to block and control the metabolism of sugar. With the increase of approved peptide-based drugs, the production of peptides will escalate. Yet, peptide manufacture companies (for peptide-based drugs), which need to be compliant with good manufacturing practices (GMP), face a several challenges, the main ones being high production costs on downstream processes (due to the use of high raw material amounts) and bad scalability. Numaferm is a German company founded in 2015 with the mission of making peptides economical for pharmaceutical markets. To tackle current challenges, we have developed two (patented) innovative technologies (NUMAtag and NUMAswitch) whose unique features are not offered by the alternatives in the market for peptide manufacture: cost-efficient production (50x reduction of manufacturing costs, under GMP); environmentally friendly process (reduced carbon foot print by >90%); scalable production (peptide scalability by ton scale with no peptide length limitation), thus enabling a high efficiency upstream and downstream process for peptide manufacture. Through the NUMA-SCALE project we aim to upscale our production and extend our commercial capabilities (by making our processes ready for tech-transfer into GMP facilities of Contract Manufacture Organizations) thus allowing us to seize more business opportunities. This project will have a massive positive impact to Numaferm – will boost our revenues (€14.8M by 2023), employability (creation of 15 new jobs) and generate new IP, allowing us to continuously venture new markets with our technology.

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The information about "NUMA-SCALE" are provided by the European Opendata Portal: CORDIS opendata.

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