Explore the words cloud of the GLADIATOR project. It provides you a very rough idea of what is the project "GLADIATOR" about.
The following table provides information about the project.
UNIVERSITY OF CYPRUS
|Coordinator Country||Cyprus [CY]|
|Total cost||6˙122˙255 €|
|EC max contribution||5˙982˙255 € (98%)|
1. H2020-EU.1.2.1. (FET Open)
|Duration (year-month-day)||from 2019-01-01 to 2022-12-31|
Take a look of project's partnership.
|1||UNIVERSITY OF CYPRUS||CY (NICOSIA)||coordinator||953˙125.00|
|2||FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.||DE (MUNCHEN)||participant||1˙758˙103.00|
|3||E.P.O.S. IASIS RESEARCH AND DEVELOPMENT LTD||CY (LEFKOSIA)||participant||1˙111˙540.00|
|4||OULUN YLIOPISTO||FI (OULU)||participant||950˙535.00|
|5||NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU||NO (TRONDHEIM)||participant||787˙076.00|
|6||WATERFORD INSTITUTE OF TECHNOLOGY||IE (Waterford)||participant||421˙875.00|
|7||OSAKA UNIVERSITY||JP (OSAKA)||participant||0.00|
Brain pathologies are highly complex disorders. Despite recent progress, their prognosis is grim, defining a high societal challenge. Bridging life sciences, bio-nanotechnology, engineering and ICT, GLADIATOR promises a vanguard and comprehensive theranostic (therapeuticdiagnostic) solution for brain malignancies. Through a multi-faceted breakthrough, GLADIATOR will provide, for the first time, a working prototype of a complete, autonomous and clinically applicable, nanonetwork-based, Molecular Communications system based on the conceptual framework of Externally Controllable Molecular Communications (ECMC). Using Glioblastoma Multiforme tumours, the most detrimental brain pathologies, as a proof-of-concept case, GLADIATOR will implement a platform of cell-based and electronic components. Implantable autologous organoids of engineered neural stem cells (iNSCs) will release rationally designed exosomal bio-nanomachines, delivering reprogramming (therapeutic) miRNAs and building nanonetworks. Interfering with the underlying biological environment, the nanonetworks will define a revolutionary intervention. A hybrid bio-electronic interface, consisting of coupled external and implantable devices, will enable communication channels with host-derived fluorescent bio-nanomachines via micro-optoelectronic sensors. The cellular, sub-cellular and electronic components will be integrated into a wireless ECMC network. This system will autonomously monitor the spatiotemporal tumour evolution and recurrence and generate, on demand, appropriate reprogramming interventions, by radiofrequency stimulation of iNSC renewal. A paradigm shift in Oncology Research is anticipated via the supra-discipline of “bio-nanomachine diagnostics”. GLADIATOR establishes a radical long-term vision leading to a drastic change in cancer therapy, also ushering the emergence of the ECMC field and transforming the burgeoning industry of Internet of Nano-bio-things, with high socioeconomic impact.
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The information about "GLADIATOR" are provided by the European Opendata Portal: CORDIS opendata.
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