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Fundamentals of Biological Ice Nucleation

Total Cost €


EC-Contrib. €






 F-BioIce project word cloud

Explore the words cloud of the F-BioIce project. It provides you a very rough idea of what is the project "F-BioIce" about.

action    frost    electron    nucleation    exert    frequency    models    mechanisms    preservation    details    interacting    soot    layers    time    back    atmosphere    spectroscopy    silica    bacteria    generation    ask    mode    combining    paradigm    dynamics    entire    molecules    largely    aerosols    microscopy    diverse    lack    cryomedicine    questions    fungi    cryo    realistic    specialized    interface    global    strategies    plant    attack    team    relevance    traced    sfg    clouds    plants    feldspar    reveal    configuration    techniques    apparent    proteins    interact    science    manipulate    disciplines    motifs    inp    molecular    seeding    active    computer    patterns    surfaces    basis    rising    freezing    input    model    cloud    abiotic    climate    surface    structure    drive    biomedicine    airborne    pollen    climatology    nucleators    search    spearheading    first    protein    elusive    food    damage    transitions    interfacial    sum    critical    bioice    monolayers    revolutionary    ice    shift    inps    nucleating    pathology    despite    structural    technologies    imprint    precipitation    remained    material    simulations    water    function   

Project "F-BioIce" data sheet

The following table provides information about the project.


Organization address
city: AARHUS C
postcode: 8000

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 1˙999˙936 €
 EC max contribution 1˙999˙936 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-04-01   to  2024-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AARHUS UNIVERSITET DK (AARHUS C) coordinator 1˙999˙936.00


 Project objective

Ice active bacteria can promote the growth of ice more effectively than any other material known. Using specialized ice nucleating proteins (INPs), they attack plants by frost damage and, when airborne in the atmosphere, they drive ice nucleation within clouds and control global precipitation patterns. The control INPs exert over water phase transitions has relevance for disciplines as diverse as climatology, plant pathology, biomedicine and material science. Despite the apparent importance, the molecular mechanisms behind INP freezing have remained largely elusive. This lack of our knowledge can be traced back to the challenges in studying protein and water structure and dynamics at the very interface between monolayers of proteins and water. With F-BioIce my team and I want to reveal the molecular details of INP function. We ask the questions: What is the structural basis for protein control of freezing? What structural motifs do proteins use to interact with water, and what is the configuration of water molecules that INPs imprint into interfacial water layers? What is the role of structural dynamics and for surface freezing? We will develop new methods based on sum frequency generation (SFG) spectroscopy to determine mode of action by which INPs interact with and manipulate water. The INPs and water structure will be obtained by combining three rising methods in the field: SFG techniques that I have been spearheading, computer simulations and cryo-electron microscopy. We will study model water surfaces and, for the first time, realistic water aerosols interacting with INPs. These new strategies could lead to a paradigm shift in the entire field of ice nucleation and a search for similar processes in ice active fungi and pollen and abiotic ice nucleators – feldspar, silica and soot. The obtained information will provide critical input for climate models and revolutionary new freezing technologies for food preservation, cryomedicine and cloud seeding.

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The information about "F-BIOICE" are provided by the European Opendata Portal: CORDIS opendata.

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