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Fundamentals of Biological Ice Nucleation

Total Cost €


EC-Contrib. €






 F-BioIce project word cloud

Explore the words cloud of the F-BioIce project. It provides you a very rough idea of what is the project "F-BioIce" about.

bioice    bacteria    damage    motifs    specialized    layers    elusive    inps    transitions    spectroscopy    action    surfaces    exert    mechanisms    remained    inp    nucleation    soot    atmosphere    frequency    realistic    function    time    combining    cloud    disciplines    feldspar    material    back    biomedicine    manipulate    molecular    nucleating    technologies    protein    shift    team    interface    patterns    science    cryo    critical    monolayers    mode    ice    lack    attack    abiotic    silica    electron    food    water    plant    sfg    revolutionary    global    structure    climate    details    model    despite    first    microscopy    freezing    basis    cryomedicine    nucleators    traced    imprint    reveal    molecules    proteins    interact    pollen    aerosols    rising    interacting    paradigm    apparent    pathology    structural    climatology    models    ask    precipitation    simulations    techniques    diverse    computer    configuration    preservation    relevance    frost    drive    seeding    surface    spearheading    largely    sum    fungi    dynamics    clouds    search    input    plants    questions    active    interfacial    strategies    generation    airborne    entire   

Project "F-BioIce" data sheet

The following table provides information about the project.


Organization address
city: AARHUS C
postcode: 8000

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 1˙999˙936 €
 EC max contribution 1˙999˙936 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-04-01   to  2024-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AARHUS UNIVERSITET DK (AARHUS C) coordinator 1˙999˙936.00


 Project objective

Ice active bacteria can promote the growth of ice more effectively than any other material known. Using specialized ice nucleating proteins (INPs), they attack plants by frost damage and, when airborne in the atmosphere, they drive ice nucleation within clouds and control global precipitation patterns. The control INPs exert over water phase transitions has relevance for disciplines as diverse as climatology, plant pathology, biomedicine and material science. Despite the apparent importance, the molecular mechanisms behind INP freezing have remained largely elusive. This lack of our knowledge can be traced back to the challenges in studying protein and water structure and dynamics at the very interface between monolayers of proteins and water. With F-BioIce my team and I want to reveal the molecular details of INP function. We ask the questions: What is the structural basis for protein control of freezing? What structural motifs do proteins use to interact with water, and what is the configuration of water molecules that INPs imprint into interfacial water layers? What is the role of structural dynamics and for surface freezing? We will develop new methods based on sum frequency generation (SFG) spectroscopy to determine mode of action by which INPs interact with and manipulate water. The INPs and water structure will be obtained by combining three rising methods in the field: SFG techniques that I have been spearheading, computer simulations and cryo-electron microscopy. We will study model water surfaces and, for the first time, realistic water aerosols interacting with INPs. These new strategies could lead to a paradigm shift in the entire field of ice nucleation and a search for similar processes in ice active fungi and pollen and abiotic ice nucleators – feldspar, silica and soot. The obtained information will provide critical input for climate models and revolutionary new freezing technologies for food preservation, cryomedicine and cloud seeding.

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The information about "F-BIOICE" are provided by the European Opendata Portal: CORDIS opendata.

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