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UnleashLupin SIGNED

Unleashing the potential of narrow leaf lupin as locally grown protein crop

Total Cost €


EC-Contrib. €






 UnleashLupin project word cloud

Explore the words cloud of the UnleashLupin project. It provides you a very rough idea of what is the project "UnleashLupin" about.

safety    candidate    gene    angustifolius    herbivores    resistant    grain    unleashlupin    qas    sustainability    discover    world    economic    eldin    curbing    narrow    significantly    expertise    locally    geu    levels    grown    atmospheric    genomics    excellent    europe    fix    dependency    lupinus    distance    combine    vegetative    tissues    flores    genes    eliminate    prevent    nour    imported    cultivation    outcome    characterise    nitrogen    instrumental    content    70    oocytes    background    will    proteins    xenopus    virus    vegetable    biosynthesis    transported    40    techniques    quinolizidine    produces    plant    thresholds    engineering    accumulates    laboratory    tested    lupin    transport    compromising    unknown    nll    interestingly    sub    cellular    crop    native    genetics    retains    planta    defenses    herbivore    cultivars    imports    surpasses    silencing    translocating    toxic    specialised    characterization    leafed    protein    little    qa    metabolite    susceptible    alkaloids    localization    metabolites   

Project "UnleashLupin" data sheet

The following table provides information about the project.


Organization address
address: NORREGADE 10
postcode: 1165

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 207˙312 €
 EC max contribution 207˙312 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-03-02   to  2022-03-01


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 207˙312.00


 Project objective

Europe is in great need of a locally produced protein crop as it imports 70% of its protein requirements. Narrow-leafed lupin (Lupinus angustifolius, NLL) represents an excellent candidate. It is native to Europe, able to fix atmospheric nitrogen and produces high-protein grain (up to 40%). However, toxic alkaloids in the grain (quinolizidine alkaloids, QAs) prevent its widespread cultivation. Cultivars with low QA levels in all tissues are available; however, these are susceptible to herbivores, and grain QA content often surpasses safety thresholds. Interestingly, QAs are not produced in the grain, but are transported to the grain from vegetative tissues. Thus, I propose to specifically eliminate QAs from grain using a transport engineering approach without compromising defenses in vegetative tissues. In this UnleashLupin project I will discover and characterise the unknown transport proteins involved in translocating QAs to the grain. For this, I will combine my background in NLL genetics and genomics with the expertise of the Nour‒Eldin laboratory, which is world-leading in the field of plant specialised metabolite transport. Candidate genes will be selected from recently generated resources, and they will be tested for transport activity (e.g. in Xenopus oocytes) and cellular/sub-cellular localization. Techniques for in planta characterization (e.g. virus-induced gene silencing) will be provided by the Geu-Flores laboratory, which is currently investigating QA biosynthesis in NLL. The outcome will significantly advance the emerging field of long-distance transport of plant specialised metabolites. It will also be instrumental in the development of a locally grown high-value, herbivore-resistant NLL crop that accumulates little or no QAs in the grain but retains QAs in vegetative tissues. Such a crop has the potential of curbing the EU’s dependency on imported vegetable protein, thus contributing to sustainability and economic growth.

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The information about "UNLEASHLUPIN" are provided by the European Opendata Portal: CORDIS opendata.

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