Opendata, web and dolomites

PROTOBAC SIGNED

Engineering of complex protocells by micro-compartmentalization of living bacteria

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 PROTOBAC project word cloud

Explore the words cloud of the PROTOBAC project. It provides you a very rough idea of what is the project "PROTOBAC" about.

compartmentalized    engineering    synthesis    assemblage    designs    last    proto    bristol    university    multidisciplinary    outcome    physical    answer    instead    suitable    functionally    question    membrane    mitochondria    expression    organization    starting    materials    rudimentary    disruption    colonies    group    forms    hosting    complexity    bound    segregation    first    structural    metabolism    active    perform    nuclear    cellular    lack    functions    manifestations    biotechnology    functional    construction    capacity    synthetic    professor    mann    precisely    sequestration    introducing    stephen    lipids    organisational    internally    inanimate    pioneering    living    efforts    bacterial    gene    protoeukaryote    few    combined    life    endomembrane    microbiology    replication    minimal    sensing    transition    compartmentalization    exhibiting    material    loaded    metabolic    components    protocell    behaviours    energy    artificial    frs    plasmids    genetic    organelles    biology    bacteria    expertise    biological    transduction    spatial    protocells   

Project "PROTOBAC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF BRISTOL 

Organization address
address: BEACON HOUSE QUEENS ROAD
city: BRISTOL
postcode: BS8 1QU
website: www.bristol.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 212˙933 €
 EC max contribution 212˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2021-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF BRISTOL UK (BRISTOL) coordinator 212˙933.00

Map

 Project objective

The engineering of artificial cellular systems (i.e. protocells) exhibiting rudimentary life-like properties, such as minimal metabolism, sensing or replication, gene expression and compartmentalization, represents the most suitable path to undertake to answer the important question on how inanimate systems can transition into proto-living manifestations of physical matter. However, most of the current protocell designs still lack the structural and organisational complexity required for them to perform advanced functions and behaviours. Instead of starting from non-living materials, the aim of this proposal is precisely to design and construction of complex multi-component protocells based on the controlled sequestration and disruption of compartmentalized living bacterial colonies. The result protocells will bound by an assemblage of bacterial membrane lipids and internally loaded with a large number of functionally active metabolic and genetic components. Furthermore, the structural and functional complexity of the bacteria-derived protocells will be increased by introducing several important biological organelles such as proto-nuclear, proto-mitochondria components and endomembrane system, which is expected to produce the first example of protoeukaryote. The previous expertise of the applicant in the field of biotechnology, synthetic biology and microbiology will be applied to the multidisciplinary and emerging field of protocells in which the hosting group of Professor Stephen Mann FRS at the University of Bristol has been pioneering over the last few years. The key outcome of the combined research efforts of the applicant and the Mann group will lead to the synthesis of bacteria derived protocells and develop their advanced forms capable of increased energy (metabolic) capacity and transduction, spatial segregation of genetic material (plasmids etc), and higher-order organization and processing.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROTOBAC" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PROTOBAC" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

POSPORI (2019)

Polymer Optical Sensors for Prolonged Overseeing the Robustness of civil Infrastructures

Read More  

ACES (2019)

Antarctic Cyclones: Expression in Sea Ice

Read More  

MarshFlux (2020)

The effect of future global climate and land-use change on greenhouse gas fluxes and microbial processes in salt marshes

Read More