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MImETIC INDiRECT SIGNED

MIcrovascularizED Tumour-on-chip for Cellular ImagiNg of Drug Response and Cell moTility

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MImETIC INDiRECT project word cloud

Explore the words cloud of the MImETIC INDiRECT project. It provides you a very rough idea of what is the project "MImETIC INDiRECT" about.

platform    biology    plates    standardization    single    solutions    integration    3d    reproducible    consist    worldwide    types    microvascularized    microfluidic    collaborations    free    chamber    disseminated    drug    tissue    acquisition    appropriate    temperature    aforementioned    lanes    complementary    diverse    skills    unconventional    organ    sensor    sub    personalized    clinical    compact    techniques    marketing    envision    discovery    standardized    biotech    medicine    cancer    accessible    adoption    designed    collagenous    platforms    indirect    migration    components    24    mitigation    formulations    dictated    commercial    strategies    sectors    risks    model    disruptive    industry    dual    multidisciplinary    live    versatile    mimetic    confocal    toxicology    direct    optional    mentioned    standardised    controller    biomimetic    imaging    toolkit    lines    microscopy    cell    cubix    culture    cherry    o2    chip    collagen    academic    collaborative    market    chips    promotes    optimized    flow    manner    scientific    cancerous    create    compatible    academia    animal    cellular   

Project "MImETIC INDiRECT" data sheet

The following table provides information about the project.

Coordinator
CHERRY BIOTECH 

Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2021-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 196˙707.00

Map

 Project objective

MImETIC INDiRECT aims to develop a standardised, accessible, versatile organ-on-chip toolkit for cancer biology and drug discovery research, compatible with microscopy-based (live imaging and confocal) techniques. The project is expected to facilitate academia and industry adoption of microfluidic 3D cell culture systems for comparable and reproducible results in a complex biomimetic animal free model for cancer drug discovery, toxicology, advanced (pre)clinical as well as personalized medicine. The toolkit components will consist of an integrated temperature controller dual-chamber chip, the Cherry Biotech CubiX system and growth factor optimized collagenous solutions for each chip chamber. The dual chamber chip, with cellular migration lanes, will have two tailored collagen-based formulations, designed per chamber. The CubiX platform is a compact flow and temperature controller, allowing optional sensor (e.g. O2) integration, compatible with single chips or 24-well plates. The cancer(s) sub-types to be used toolkit standardization will be dictated by market needs, where commercial cell lines (cancerous and non-cancerous) will be used to create the microvascularized complex tissue model. Potential project risks have been identified with appropriate mitigation strategies, where the project promotes adoption of standardized, cost-effective and versatile cancer organ-on-chip platforms in the market, rather than disruptive academic findings. Access of the aforementioned system to a worldwide growth market will fully exploit the project results, disseminated by direct and indirect marketing and scientific approaches. Project implementation will be an academic-industry collaborative and multidisciplinary manner providing the acquisition of diverse and unconventional complementary skills, leading to an understanding of both sectors requirements. We envision the above-mentioned to facilitate future academic and industry collaborations.

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The information about "MIMETIC INDIRECT" are provided by the European Opendata Portal: CORDIS opendata.

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