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MImETIC INDiRECT SIGNED

MIcrovascularizED Tumour-on-chip for Cellular ImagiNg of Drug Response and Cell moTility

Total Cost €

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EC-Contrib. €

0

Partnership

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 MImETIC INDiRECT project word cloud

Explore the words cloud of the MImETIC INDiRECT project. It provides you a very rough idea of what is the project "MImETIC INDiRECT" about.

direct    model    discovery    animal    cancer    culture    collaborative    marketing    cellular    confocal    multidisciplinary    disseminated    biomimetic    cubix    3d    techniques    acquisition    accessible    academic    envision    skills    optimized    consist    collagenous    aforementioned    adoption    microscopy    clinical    standardized    mitigation    controller    migration    promotes    complementary    flow    disruptive    collaborations    types    chamber    strategies    designed    chip    drug    scientific    mimetic    market    standardised    unconventional    manner    optional    diverse    commercial    worldwide    cherry    versatile    indirect    plates    sectors    collagen    24    formulations    compatible    mentioned    cancerous    appropriate    platforms    create    industry    standardization    sensor    single    sub    compact    risks    platform    free    live    academia    medicine    organ    temperature    chips    cell    components    microfluidic    personalized    lines    lanes    toxicology    microvascularized    integration    solutions    toolkit    biology    dual    reproducible    biotech    o2    dictated    tissue    imaging   

Project "MImETIC INDiRECT" data sheet

The following table provides information about the project.

Coordinator
CHERRY BIOTECH 

Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2021-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 196˙707.00

Map

 Project objective

MImETIC INDiRECT aims to develop a standardised, accessible, versatile organ-on-chip toolkit for cancer biology and drug discovery research, compatible with microscopy-based (live imaging and confocal) techniques. The project is expected to facilitate academia and industry adoption of microfluidic 3D cell culture systems for comparable and reproducible results in a complex biomimetic animal free model for cancer drug discovery, toxicology, advanced (pre)clinical as well as personalized medicine. The toolkit components will consist of an integrated temperature controller dual-chamber chip, the Cherry Biotech CubiX system and growth factor optimized collagenous solutions for each chip chamber. The dual chamber chip, with cellular migration lanes, will have two tailored collagen-based formulations, designed per chamber. The CubiX platform is a compact flow and temperature controller, allowing optional sensor (e.g. O2) integration, compatible with single chips or 24-well plates. The cancer(s) sub-types to be used toolkit standardization will be dictated by market needs, where commercial cell lines (cancerous and non-cancerous) will be used to create the microvascularized complex tissue model. Potential project risks have been identified with appropriate mitigation strategies, where the project promotes adoption of standardized, cost-effective and versatile cancer organ-on-chip platforms in the market, rather than disruptive academic findings. Access of the aforementioned system to a worldwide growth market will fully exploit the project results, disseminated by direct and indirect marketing and scientific approaches. Project implementation will be an academic-industry collaborative and multidisciplinary manner providing the acquisition of diverse and unconventional complementary skills, leading to an understanding of both sectors requirements. We envision the above-mentioned to facilitate future academic and industry collaborations.

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The information about "MIMETIC INDIRECT" are provided by the European Opendata Portal: CORDIS opendata.

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