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MIcrovascularizED Tumour-on-chip for Cellular ImagiNg of Drug Response and Cell moTility

Total Cost €


EC-Contrib. €






 MImETIC INDiRECT project word cloud

Explore the words cloud of the MImETIC INDiRECT project. It provides you a very rough idea of what is the project "MImETIC INDiRECT" about.

discovery    envision    controller    cell    microvascularized    migration    types    cancerous    collagenous    disruptive    collaborative    create    medicine    manner    acquisition    optional    components    compatible    single    complementary    reproducible    academia    24    cubix    organ    appropriate    clinical    disseminated    platforms    live    biomimetic    aforementioned    standardised    unconventional    drug    collaborations    lines    cellular    o2    compact    solutions    diverse    free    versatile    academic    microfluidic    platform    strategies    optimized    scientific    indirect    accessible    toxicology    culture    model    chips    personalized    mitigation    cherry    commercial    direct    adoption    chip    multidisciplinary    sectors    consist    industry    mimetic    confocal    standardization    designed    dictated    chamber    market    plates    toolkit    formulations    mentioned    collagen    3d    cancer    marketing    standardized    imaging    sensor    biotech    animal    biology    risks    worldwide    dual    skills    flow    promotes    sub    integration    lanes    tissue    techniques    temperature    microscopy   

Project "MImETIC INDiRECT" data sheet

The following table provides information about the project.


Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2021-07-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 196˙707.00


 Project objective

MImETIC INDiRECT aims to develop a standardised, accessible, versatile organ-on-chip toolkit for cancer biology and drug discovery research, compatible with microscopy-based (live imaging and confocal) techniques. The project is expected to facilitate academia and industry adoption of microfluidic 3D cell culture systems for comparable and reproducible results in a complex biomimetic animal free model for cancer drug discovery, toxicology, advanced (pre)clinical as well as personalized medicine. The toolkit components will consist of an integrated temperature controller dual-chamber chip, the Cherry Biotech CubiX system and growth factor optimized collagenous solutions for each chip chamber. The dual chamber chip, with cellular migration lanes, will have two tailored collagen-based formulations, designed per chamber. The CubiX platform is a compact flow and temperature controller, allowing optional sensor (e.g. O2) integration, compatible with single chips or 24-well plates. The cancer(s) sub-types to be used toolkit standardization will be dictated by market needs, where commercial cell lines (cancerous and non-cancerous) will be used to create the microvascularized complex tissue model. Potential project risks have been identified with appropriate mitigation strategies, where the project promotes adoption of standardized, cost-effective and versatile cancer organ-on-chip platforms in the market, rather than disruptive academic findings. Access of the aforementioned system to a worldwide growth market will fully exploit the project results, disseminated by direct and indirect marketing and scientific approaches. Project implementation will be an academic-industry collaborative and multidisciplinary manner providing the acquisition of diverse and unconventional complementary skills, leading to an understanding of both sectors requirements. We envision the above-mentioned to facilitate future academic and industry collaborations.

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The information about "MIMETIC INDIRECT" are provided by the European Opendata Portal: CORDIS opendata.

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