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SHINEShift SIGNED

Shape-shifting of vesicles induced by artificial tubular networks

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SHINEShift project word cloud

Explore the words cloud of the SHINEShift project. It provides you a very rough idea of what is the project "SHINEShift" about.

ones    horizontal    fluid    stiff    consisting    responsive    pushing    organic    scientific    stops    synthetic    notable    expertise    models    me    structures    reversible    mechanical    fueling    static    disassemble    transforming    surrounding    interdisciplinary    artificial    supramolecular    leap    photo    edge    material    peptide    cytoskeleton    forces    progress    dynamic    disciplines    shape    manner    lipid    cyclic    switchable    transferable    chemistry    spread    made    cutting    biology    kudernac    cells    environment    assemblies    fuel    cell    relevance    stimuli    microfluidics    preparation    host    synthesis    fellowship    techniques    tubules    hence    researcher    expand    training    skills    vesicles    brings    competitive    grow    inside    microscopy    leadership    resisting    distinctive    objects    fundamental    passive    msca    time    dr    poor    stress    science    compounds    colloidal    generate    membrane    stabilizing    bilayer   

Project "SHINEShift" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 187˙572 €
 EC max contribution 187˙572 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 187˙572.00

Map

 Project objective

The most commonly used artificial cell membrane models are vesicles. However, these static structures, consisting of a lipid bilayer surrounding a fluid, are poor in resisting mechanical stress. Enhancing their mechanical properties with a dynamic artificial cytoskeleton will both allow stabilizing their shape and transforming these passive objects into dynamic stimuli-responsive systems. In this MSCA project photo-responsive synthetic supramolecular tubules will be used as an artificial cytoskeleton inside vesicles. My aim is to develop stiff and at the same time responsive tubules based on cyclic peptide design that can grow and generate pushing forces during the fueling step, and disassemble when the fuel stops, both in a fully reversible manner. This cutting edge interdisciplinary project brings together several disciplines in chemistry, i.e. organic synthesis and supramolecular chemistry with colloidal chemistry (and/or microfluidics), and its scientific impact will spread through various fields – from supramolecular chemistry to material science (leap from static vesicles to dynamic ones), and synthetic biology (relevance for future applications in the field of artificial cells). My expertise as experienced researcher in the field of organic synthesis will be applied to the field of dynamic supramolecular systems based on photo-switchable compounds in which the host (Dr. Kudernac) has made notable recent progress. During this training-through-research project I will be able to learn the preparation processes for the vesicles and microscopy techniques that are fundamental for investigating (dynamic) supramolecular assemblies and which will further expand my horizontal skills. In addition, training activities during this fellowship will strongly enhance my leadership and transferable skills. Hence, the Fellowship will allow me to become a distinctive researcher in a highly competitive scientific environment.

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The information about "SHINESHIFT" are provided by the European Opendata Portal: CORDIS opendata.

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