DNA-NANO-AB SIGNED
“DNA-based NANOdevices for the point-of-care electrochemical detection of AntiBodies”
Total Cost €
0EC-Contrib. €
0Partnership
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0DNA-NANO-AB project word cloud
Explore the words cloud of the DNA-NANO-AB project. It provides you a very rough idea of what is the project "DNA-NANO-AB" about.
Project "DNA-NANO-AB" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Organization address contact info |
| Coordinator Country | Italy [IT] |
| Total cost | 251˙002 € |
| EC max contribution | 251˙002 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2018 |
| Funding Scheme | MSCA-IF-GF |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-03-01 to 2023-02-28 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA | IT (ROMA) | coordinator | 251˙002.00 |
| 2 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | US (OAKLAND CA) | partner | 0.00 |
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Project objective
WHY: Antibody detection plays a pivotal role in the diagnosis of many human disorders including infectious, autoimmune, and oncological diseases. Unfortunately, current methods routinely used for the detection of these biomarkers still require sophisticated equipment, washing intensive, reagent-intensive multi-step processes. In attempt to overcome the cited limitations, it’s mandatory find new approaches for the sensitive detection of antibodies. WHAT: DNA-NANO-AB proposes the development of DNA-based novel, rapid, user friendly, robust, sensitive and low cost electrochemical NANOdevices for orthogonal multiplex detection of antibodies that may be advantageous over existing methods for the detection of clinically-relevant antibodies and could be well-positioned for point-of-care applications. I will achieve this goal by rationally designing and fabricating disposable DNA-based sensing platforms in which the detection of specific antibodies will be signaled, and amplified, through an electrochemical read-out approach. The developed platforms will be characterized, optimized and then tested for the dosage of immunoglobulins levels directly in real representative samples. HOW: During the fellowship I will undertake a training program to develop skills and acquire expertise in molecular biology, electrochemical biosensor and DNA Nanotechnology. To achieve these objectives, I will combine the different scientific backgrounds and expertise of two leading scientists: Prof. Plaxco (University of California Santa Barbara), a world-wide expert in electrochemical biosensors, and Prof. Ricci (University of Rome, Tor Vergata), a young researcher active at the forefront of DNA nanotechnology for diagnostic and drug-delivery applications. Thanks to this MSC Fellowship, I will diversify my scientific knowledge and acquire cutting-edge competences as well as complementary skills, which will become the foundation of my scientific independence.
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The information about "DNA-NANO-AB" are provided by the European Opendata Portal: CORDIS opendata.