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LUCENT SIGNED

superbright, photostabLe and mUlticolour novel fluoresCent mEtal quaNtum clusters for super-resoluTion imaging

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 LUCENT project word cloud

Explore the words cloud of the LUCENT project. It provides you a very rough idea of what is the project "LUCENT" about.

structures    biology    engineered    nanometric    generation    atomic    single    host    dimensional    suitable    biological    nanomedicine    combination    molecular    resolution    probes    synthesis    super    images    preliminary    researcher    binding    levels    live    revolutionized    fluorophore    techniques    molecule    model    prerequisites    framework    strategies    brightness    markers    property    despite    strength    designed    emission    clusters    strategy    fluorescent    accuracy    nanoscopy    idea    multidiscicplinary    nanotechnology    stimulated    resides    nanoscopic    synthetic    toxicity    photoswitching    setup    optical    breakthrough    emergent    photostability    surface    utilized    employ    multicolour    routes    endowed    visualize    reversible    metal    expertise    quantum    play    complementary    cellular    purpose    nanochemistry    photoluminescent    microscopy    deeper    ultrasmall    unmet    producing    biocompatibility    successful    imaging    lucent    realistically    basis   

Project "LUCENT" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT EINDHOVEN 

Organization address
address: GROENE LOPER 3
city: EINDHOVEN
postcode: 5612 AE
website: www.tue.nl/en

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 175˙572 €
 EC max contribution 175˙572 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2021-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) coordinator 175˙572.00

Map

 Project objective

The breakthrough of super resolution imaging has revolutionized biology and nanomedicine, allowing to visualize synthetic or biological structures with nanometric accuracy and providing a deeper understanding of complex molecular systems. The key idea at the basis of these methods is the use of novel fluorescent markers endowed with specific properties such as photoswitching, reversible binding, stimulated emission and single molecule imaging capabilities. In this emergent framework the fluorescent markers play a role as important as the optical setup utilized for imaging. Therefore, among the prerequisites for successful nanoscopic imaging the selection of the suitable fluorophore is essential. Despite the recent advances in the development of super-resolution microscopy techniques, fluorescent probes with high brightness, high photostability and low toxicity remains an unmet need. This proposal aims at developing ultrasmall photoluminescent atomic metal quantum clusters as new generation of advanced optical probes for super-resolution microscopy. To this purpose, we will apply a combination of property-designed nanochemistry routes and surface engineered strategies for producing multicolour atomic metal clusters that will provide novel model systems for single molecule imaging. The strategy will focus at three important levels: synthesis, biocompatibility and preliminary cellular imaging, application in super-resolution microscopy. The research activity here proposed could realistically lead to live, multicolour, three-dimensional images with an even higher resolution – down to the molecular level – with applications in biology and nanotechnology. To this end, LUCENT will employ a multidiscicplinary approach whose strength resides in the combination of the complementary expertise of the experienced researcher –design of new probes - and the host institution - nanoscopy.

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The information about "LUCENT" are provided by the European Opendata Portal: CORDIS opendata.

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