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LUCENT SIGNED

superbright, photostabLe and mUlticolour novel fluoresCent mEtal quaNtum clusters for super-resoluTion imaging

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 LUCENT project word cloud

Explore the words cloud of the LUCENT project. It provides you a very rough idea of what is the project "LUCENT" about.

play    dimensional    photostability    biological    endowed    ultrasmall    property    super    nanomedicine    routes    structures    metal    generation    quantum    emergent    levels    photoluminescent    accuracy    biocompatibility    basis    revolutionized    cellular    optical    producing    despite    nanoscopic    preliminary    strength    surface    successful    resides    images    techniques    strategy    prerequisites    live    reversible    imaging    unmet    molecule    synthetic    markers    stimulated    clusters    resolution    utilized    setup    combination    expertise    microscopy    framework    lucent    complementary    host    engineered    molecular    binding    single    employ    nanoscopy    strategies    multidiscicplinary    biology    emission    idea    suitable    purpose    nanochemistry    nanometric    fluorophore    toxicity    photoswitching    atomic    designed    visualize    synthesis    brightness    nanotechnology    researcher    probes    realistically    fluorescent    deeper    multicolour    model    breakthrough   

Project "LUCENT" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT EINDHOVEN 

Organization address
address: GROENE LOPER 3
city: EINDHOVEN
postcode: 5612 AE
website: www.tue.nl/en

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 175˙572 €
 EC max contribution 175˙572 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2021-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) coordinator 175˙572.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

The breakthrough of super resolution imaging has revolutionized biology and nanomedicine, allowing to visualize synthetic or biological structures with nanometric accuracy and providing a deeper understanding of complex molecular systems. The key idea at the basis of these methods is the use of novel fluorescent markers endowed with specific properties such as photoswitching, reversible binding, stimulated emission and single molecule imaging capabilities. In this emergent framework the fluorescent markers play a role as important as the optical setup utilized for imaging. Therefore, among the prerequisites for successful nanoscopic imaging the selection of the suitable fluorophore is essential. Despite the recent advances in the development of super-resolution microscopy techniques, fluorescent probes with high brightness, high photostability and low toxicity remains an unmet need. This proposal aims at developing ultrasmall photoluminescent atomic metal quantum clusters as new generation of advanced optical probes for super-resolution microscopy. To this purpose, we will apply a combination of property-designed nanochemistry routes and surface engineered strategies for producing multicolour atomic metal clusters that will provide novel model systems for single molecule imaging. The strategy will focus at three important levels: synthesis, biocompatibility and preliminary cellular imaging, application in super-resolution microscopy. The research activity here proposed could realistically lead to live, multicolour, three-dimensional images with an even higher resolution – down to the molecular level – with applications in biology and nanotechnology. To this end, LUCENT will employ a multidiscicplinary approach whose strength resides in the combination of the complementary expertise of the experienced researcher –design of new probes - and the host institution - nanoscopy.

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The information about "LUCENT" are provided by the European Opendata Portal: CORDIS opendata.

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