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IMMUcan SIGNED

Integrated IMMUnoprofiling of large adaptive CANcer patients cohorts

Total Cost €

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EC-Contrib. €

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Partnership

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 IMMUcan project word cloud

Explore the words cloud of the IMMUcan project. It provides you a very rough idea of what is the project "IMMUcan" about.

sustainability    immune    immunoprofiling    collection    majority    clinical    accessibility    saliva    failures    seq    relevance    rna    recruiting    inclusive    tissues    framework    industry    analyze    human    lung    platform    rationale    tumor    cytoff    immuno    uniform    cell    quality    sops    peptidogenomics    processed    technologies    mobilize    pursue    gastric    reproducibility    ethical    expert    tumour    academic    treatment    breast    trials    start    follow    na    data    biomarker    colorectal    generating    population    biological    interaction    oncology    plan    biobank    therapies    ten    absence    cutting    predictive    proofed    proposes    cancers    single    functioning    patients    investigations    volumes    contractual    centers    immunotherapy    independent    host    inhibitors    stool    stored    period    samples    centralized    perform    head    neck    microbiome    tissue    checkpoints    blood    material    academia    combination    types    understand    utilizing    immucan    database    running    workflow    iuml    assembled    ve    edge   

Project "IMMUcan" data sheet

The following table provides information about the project.

Coordinator
EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER AISBL 

Organization address
address: Avenue E. Mounier 83
city: Brussels
postcode: 1200
website: www.eortc.be

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 34˙937˙500 €
 EC max contribution 17˙830˙000 € (51%)
 Programme 1. H2020-EU.3.1.7. (Innovative Medicines Initiative 2 (IMI2))
 Code Call H2020-JTI-IMI2-2017-13-two-stage
 Funding Scheme IMI2-RIA
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER AISBL BE (Brussels) coordinator 7˙246˙773.00
2    LUXEMBOURG INSTITUTE OF HEALTH LU (LUXEMBOURG) participant 2˙749˙727.00
3    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 1˙712˙880.00
4    CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS CH (LAUSANNE) participant 1˙460˙332.00
5    SIB INSTITUT SUISSE DE BIOINFORMATIQUE CH (GENEVE) participant 1˙323˙000.00
6    KING'S COLLEGE LONDON UK (LONDON) participant 765˙066.00
7    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 628˙320.00
8    UNIVERSITAT ZURICH CH (ZURICH) participant 573˙700.00
9    INSTITUT CURIE FR (PARIS) participant 410˙000.00
10    FORUM EUROPEEN DES PATIENTS (FPE) LU (LUXEMBOURG) participant 250˙000.00
11    FUNDACIO CENTRE DE REGULACIO GENOMICA ES (BARCELONA) participant 190˙200.00
12    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 160˙000.00
13    LIGUE NATIONALE CONTRE LE CANCER FR (PARIS) participant 120˙000.00
14    CENTRE DE LUTTE CONTRE LE CANCER LEON BERARD FR (LYON) participant 100˙000.00
15    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) participant 100˙000.00
16    CHARITE - UNIVERSITAETSMEDIZIN BERLIN DE (BERLIN) participant 20˙000.00
17    INSTITUT JULES BORDET BE (BRUXELLES) participant 20˙000.00
18    ABBVIE INC US (NORTH CHICAGO IL) participant 0.00
19    BAYER AKTIENGESELLSCHAFT DE (Leverkusen) participant 0.00
20    DE DUVE INSTITUTE BE (BRUXELLES) participant 0.00
21    Eli Lilly and Company Limited UK (Basingstoke) participant 0.00
22    GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD. UK (BRENTFORD) participant 0.00
23    INSTITUT DE RECHERCHE PIERRE FABRESAS FR (BOULOGNE BILLANCOURT) participant 0.00
24    INSTITUT DE RECHERCHES INTERNATIONALES SERVIER FR (SURESNES) participant 0.00
25    JANSSEN PHARMACEUTICA NV BE (BEERSE) participant 0.00
26    MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN DE (DARMSTADT) participant 0.00
27    OWKIN FRANCE FR (PARIS) participant 0.00
28    SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT FR (Chilly Mazarin) participant 0.00

Map

 Project objective

IMMUcan proposes an inclusive and integrated European immuno-oncology platform. IMMUcan will access high-quality human biological material (tissue, blood, stool and saliva) and clinical data from patients with colorectal, lung, head & neck, breast, gastric cancers and immune checkpoints inhibitors failures. We have assembled a strong consortium with ten expert clinical centers, access to large volumes of the required tumor types. IMMUcan will mobilize the majority of academic trials running or expected to start recruiting patients during the project period. A centralized workflow for samples, via a state-of-the-art biobank will increase reproducibility as all tissues will be processed and stored in a uniform way, following proofed SOPs. The project will perform in depth immunoprofiling with cutting edge technologies including CyTOFF, single cell RNA-seq, peptidogenomics or microbiome analysis. IMMUcan will analyze the data in order to understand the host/tumour interaction in the absence of treatment (naïve population) and with treatment (patients in follow-up) to identify potential predictive biomarker for response to immunotherapy, or develop rationale for combination therapies. IMMUcan will provide an IT platform and legal/ethical contractual framework where participants from both academia and industry can pursue their own independent investigations utilizing the IMMUcan data and effectively testing and improving the functioning and relevance of the database. A sustainability plan will be developed to ensure the collection of follow-up data and the accessibility of the data platform. The use of the data generating throughout this project, for future research, will be supported.

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The information about "IMMUCAN" are provided by the European Opendata Portal: CORDIS opendata.

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