Opendata, web and dolomites

OLECAT SIGNED

Development of Stereoselective Olefin Functionalization Methods

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 OLECAT project word cloud

Explore the words cloud of the OLECAT project. It provides you a very rough idea of what is the project "OLECAT" about.

convert    patterns    acids    regard    boronic    incorporate    carboxylic    azides    stereochemically    chemical    oxidation    starting    cyclic    utilize    fragments    enantioselective    structures    amines    economically    discovery    trienes    carnitine    aldol    readily    routes    chiral    tenable    structural    polyols    collection    dienes    furans    classes    discover    chemo    pyrrolidines    medicines    blocks    agents    stereochemical    saturated    executed    mn    co    enantioselectivity    found    materials    fe    beneficial    catalyst    serve    small    allylation    functionalization    convergent    pharma    piperidines    catalytic    olefin    boric    pyrans    convenient    synthesis    substantially    building    form    acyclic    regio    earth    nutraceuticals    catalysts    diastereo    molecule    hydrazines    bicyclic    time    ligands    active    strategies    abundant    sustainable    optically    efficient    reactions    unsaturated    alcohols    olefinic    environmentally    settings    bioactive    nitriles    preparation    metals    easily   

Project "OLECAT" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 2˙498˙635 €
 EC max contribution 2˙498˙635 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-ADG
 Funding Scheme ERC-ADG
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2024-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 2˙498˙635.00

Map

 Project objective

The ability toThe ability to readily access small-molecule building blocks at will has important consequences for the discovery and development of novel medicines and materials. It is particularly beneficial when the chemical methods are convenient while at the same time economically and environmentally tenable and sustainable. We are especially interested in catalytic processes that are easily executed and utilize readily available starting materials to produce optically active products with high regio, chemo, diastereo, and enantioselectivity. The proposal aims to discover, develop, and study a collection of enantioselective olefin functionalization reactions that provide access to useful building blocks, such as amines, azides, hydrazines, nitriles, alcohols, involving acyclic, cyclic and bicyclic structures. The catalyst will be derived from earth abundant metals, such as Fe, Mn, and Co and incorporate novel chiral ligands. The study includes the design and preparation of two structural classes of novel, chiral boric acids that are expected to serve as catalyst for the enantioselective functionalization of unsaturated carboxylic acids and boronic acids. The methods are expected to substantially impact the development of novel strategies for complex molecule synthesis. In this regard, we propose to use the catalysts form this study to convert dienes and trienes into polyols with characteristic stereochemical and oxidation patterns found in bioactive agents, including pharma- and nutraceuticals (carnitine). Such advances enable new approaches that go beyond the well-established methods such as aldol/allylation for the preparation of stereochemically complex fragments. Catalysts will also be developed that convert acyclic olefinic alcohols and amines into optically active, saturated furans, pyrans, pyrrolidines, and piperidines. The implementation of the various catalytic methods in complex settings enables efficient, convergent routes to bioactive agents.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "OLECAT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "OLECAT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

E-DIRECT (2020)

Evolution of Direct Reciprocity in Complex Environments

Read More  

DOUBLE-TROUBLE (2020)

Replaying the ‘genome duplication’ tape of life: the importance of polyploidy for adaptation in a changing environment

Read More  

ARCTIC (2020)

Air Transport as Information and Computation

Read More