Explore the words cloud of the SMARTBOX project. It provides you a very rough idea of what is the project "SMARTBOX" about.
The following table provides information about the project.
BIO BASE EUROPE PILOT PLANT VZW
|Coordinator Country||Belgium [BE]|
|Total cost||4˙511˙562 €|
|EC max contribution||3˙924˙163 € (87%)|
1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.3.2. (SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy)
|Duration (year-month-day)||from 2019-05-01 to 2023-04-30|
Take a look of project's partnership.
|1||BIO BASE EUROPE PILOT PLANT VZW||BE (DESTELDONK GENT)||coordinator||885˙375.00|
|2||KATHOLIEKE UNIVERSITEIT LEUVEN||BE (LEUVEN)||participant||807˙750.00|
|3||RIJKSUNIVERSITEIT GRONINGEN||NL (GRONINGEN)||participant||418˙867.00|
|4||AVA BIOCHEM BSL AG||CH (MUTTENZ)||participant||391˙875.00|
|5||UNIVERSIDADE NOVA DE LISBOA||PT (LISBOA)||participant||325˙521.00|
|6||QUANTIS||CH (ECUBLENS VD)||participant||322˙500.00|
|7||UNIVERSITA DEGLI STUDI DI PAVIA||IT (PAVIA)||participant||303˙750.00|
|9||ZYMVOL BIOMODELING SL||ES (LLEIDA)||participant||206˙125.00|
|10||BORREGAARD AS||NO (SARPSBORG)||participant||0.00|
|11||COVESTRO DEUTSCHLAND AG||DE (LEVERKUSEN)||participant||0.00|
Although they have the potential to improve the economic and environmental sustainability of biorefineries, oxidative enzymes have not experienced a complete breakthrough yet in the biobased industries. This is mainly caused by the high cost and long time associated with traditional enzyme engineering methods such as directed evolution. SMARTBOX will develop an advanced computational engineering platform specifically for oxidative enzymes, which can automatically screen for improved enzyme variants with minimal human intervention. This is achieved by implementing several innovations into current computational screening methods, most importantly machine learning, which allows to train the algorithms with experimental results. As this significantly improves computational predictability, the time and costs associated with oxidative enzyme engineering will be reduced 10-fold compared to state-of-the-art (SOTA) directed evolution methods.
Relying on the advanced engineering platform, SMARTBOX will develop the one-enzyme conversion of HMF into FDCA and intermediates, and the one-enzyme conversion of lignin monomers into a potential biobased building block for polycarbonates and vanillin. By adopting a 1-enzyme FDCA production process, the associated production costs and carbon footprint are expected to decrease significantly compared to SOTA chemical oxidation methods. The unique feature of SMARTBOX is that reductive catalytic fractionation (RCF) will be used to selectively produce specific lignin monomers from biomass in near theoretical yields. The structural similarity of the resulting monomers with the SMARTBOX building blocks allows the development of high-yielding processes with only one enzyme. Due to the smart combination between oxidative biocatalysis and RCF, the production of bio-aromatics will proceed with higher yields than the state of the art.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SMARTBOX" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (firstname.lastname@example.org) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "SMARTBOX" are provided by the European Opendata Portal: CORDIS opendata.