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Hyalcis

Hyaluronic-Cisplatin Film for Implant in Malignant Mesothelioma Recurrence

Total Cost €

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EC-Contrib. €

0

Partnership

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 Hyalcis project word cloud

Explore the words cloud of the Hyalcis project. It provides you a very rough idea of what is the project "Hyalcis" about.

release    situ    feasibility    proposing    prolonged    years    market    aggressive    reaching    designation    people    preparation    america    solution    business    asbestos    months    feedback    combined    successfully    disease    japan    surfaces    resistant    medical    confirmed    introduces    competitors    thin    sufficiently    orphan    achievable    industry    qualified    hydrophilic    north    entitles    pleural    local    form    precisely    effectiveness    pleura    financial    drug    rare    difficult    film    linked    medicinal    extremely    planning    epithelial    die    benefits    worldwide    prevention    anticancer    capture    treat    protection    construction    43    satisfactory    mesothelioma    treatment    mesothelial    full    recovery    districts    curative    surgery    innovative    cancer    registration    opportunity    plan    residual    australia    toxicity    polymeric    animals    intrapleural    flexible    agency    malignant    25    company    adhering    biodegradable    safety    tests    obtaining    tumor    industrialization    200m    recurrence    provider    limiting    cisplatin    plumestars    concentrations    hyalcis    2016    efficiency    diagnose   

Project "Hyalcis" data sheet

The following table provides information about the project.

Coordinator
PLUMESTARS SRL 

Organization address
address: STRADA INZANI 1
city: PARMA PR
postcode: 43124
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.plumestars.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2019-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PLUMESTARS SRL IT (PARMA PR) coordinator 50˙000.00

Map

 Project objective

Hyalcis is a novel medicinal product, based on an innovative biodegradable film technology, for the prevention of the recurrence after surgery of malignant pleural mesothelioma. The proposing company, PlumeStars s.r.l., has successfully applied to the European Medical Agency, obtaining in 2016 the orphan designation for Hyalcis. This entitles PlumeStars as unique provider of the product, i.e, a polymeric film to treat pleura mesothelioma, for which there are no satisfactory curative methods. To capture this unique business opportunity, the Phase 1 project will develop a detailed Business Plan achievable within 6 months, including technical feasibility assessment based on qualified feedback and requirements from users, detailed market analysis, competitors analysis, industrialization planning, key partnerships preparation, knowledge protection and financial planning. Mesothelioma is a very aggressive form of cancer linked to asbestos use in construction and industry. It is difficult to diagnose, highly resistant to treatment and full recovery is extremely rare. Over 43,000 people die every year worldwide for the disease and that 10,000 new cases of mesothelioma combined in Europe, North America, Japan and Australia occur each year. The solution developed by PlumeStars is a hydrophilic, thin and flexible film, sufficiently resistant to be applied intrapleural or in other districts, adhering to the mesothelial or epithelial surfaces. The cisplatin release from the film is prolonged providing high local concentrations of anticancer drug, precisely in situ where the residual tumor could develop. This introduces significant benefits in terms of effectiveness, limiting tumor recurrence, low toxicity and increased safety and efficiency. This benefits have been confirmed in the tests already carried out on animals. PlumeStars aims at reaching 25% of the 200M€/year target market in 5 years, including 2 years for industrialization and registration.

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The information about "HYALCIS" are provided by the European Opendata Portal: CORDIS opendata.

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