Opendata, web and dolomites


The first ultrasound-compatible cranial prosthesis enabling diagnostic and therapeutic use of ultrasound in brain pathologies

Total Cost €


EC-Contrib. €






 INTRA project word cloud

Explore the words cloud of the INTRA project. It provides you a very rough idea of what is the project "INTRA" about.

treatments    biomedical    performed    consolidate    forcing    medical    savings    blood    lists    standard    certification    cheaper    bbb    full    adjuvant    pathology    diseases    accurately    plan    replace    made    unavailable    therapies    specialized    chemotherapy    transparent    implants    model    patented    mesh    customers    fda    cancer    engineering    hospital    prosthesis    national    hifu    effectiveness    health    flap    mri    craniotomies    barrier    neurodegenerative    follow    waiting    implantable    business    lesions    brain    260    start    efficacy    machine    titanium    machines    mark    intelligenza    expensive    patients    tumours    benefits    skull    device    marketing    opening    image    bone    remove    ultrasound    trespass    potentiality    usa    radiotherapy    scans    first    italian    ultrasounds    diagnostic    market    injuries    precisely    clearance    commercialize    imaging    limited    trasparente    neurosurgical    assessing    treat    streamline    strategy    unleash    plastics   

Project "INTRA" data sheet

The following table provides information about the project.


Organization address
city: MONZA
postcode: 20900
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-04-01   to  2019-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INTELLIGENZA TRANSPARENTE S. R. L. IT (MONZA) coordinator 50˙000.00


 Project objective

260,000 craniotomies are performed each year in Europe and USA to remove brain tumours and treat brain lesions and injuries. The implants used to replace the flap bone are currently made in plastics and titanium mesh, which are not transparent to ultrasounds (US), meaning that US cannot trespass them. Intelligenza Trasparente is an Italian start-up specialized in biomedical engineering and neurosurgical image-processing which has developed and patented INTRA, the first implantable prosthesis that allows ultrasound (US) to trespass the skull after neurosurgical procedures. INTRA allows to replace MRI scans (the standard brain imaging method) with US scans for the diagnostic follow-up of the brain pathology (in particular) and for assessing the effectiveness of adjuvant cancer therapies, e.g. chemotherapy and radiotherapy. MRI machines and scans are very expensive, and they availability is limited, forcing patients to long waiting lists. US scans have the same imaging efficacy, but are much cheaper, and the machine are available in every hospital. The result is significant savings for National Health Systems. More importantly, INTRA will enable the use of effective treatments of both cancer and neurodegenerative diseases which are currently unavailable for brain due to the skull barrier to ultrasound, like HIFU, and will unleash the full potentiality of ultrasound for opening the Blood Brain Barrier (BBB). The Phase 1 project will be key to define and accurately plan the next certification steps required to commercialize the product (EU mark for medical device and FDA clearance in US). We will also consolidate the business model, precisely assess the expected benefits for the customers, analyse the potential market, and streamline the marketing and distribution strategy.

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The information about "INTRA" are provided by the European Opendata Portal: CORDIS opendata.

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